the National Key Research and Development Program of China(2016YFD0101801);the National Natural Science Foundation of China(91735303 and 91335103);the Natural Science Foundation of Zhejiang(LY18C130010,LY18C130009,and LY20C130004);the Science and Technology Project of Hangzhou(20180432B03,20180432B09,and 20180432B04);the Foundation of Zhejiang Education Department(Y201431296)。
It is well established that an abnormal tetrahydrofolate(THF)cycle causes the accumulation of hydrogen peroxide(H_(2)O_(2))and leaf senescence,however,the molecular mechanism underlying this relationship remains large...
Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cjoc.201100628 or from the author.Acknowledgement We are very grateful for the support of this work from the National Natural Science Foundation of China (Nos. 20802056, 21072158) and the Special Foundation of the Education Committee of Shaanxi Province (No. 09JK750).
Since the early studies of Mannich, Mannich reaction has become an important tool for the synthesis of new compounds. Mannich bases can be either directly employed or used as intermediates. In this work, the one-carbo...
Objective To review the association of methylene tetrahydrofolate reductase (MTHFR) C677T mutant with coronary artery disease, as well as to highlight the results of some of these studies and to emphasize the need to ...
This work was supported by the National Natural Science Foundation of China(NO.20172041);Provincial Natural Science Foundation of Shaanxi Province.
The addition-hydrolysis reaction of benzimidazolium salt with some mono- and bifunctional amine nucleophiles is reported, and a novel method of biomimetic synthesis for formamides and heterocycle compounds is provided.
The hydrolysis products of tetrahydrofolate model compound 4 were a mixture of 6 and 7 and the rearrangement reaction between 6 and 7 via 5 was in a state of equilibrium, confirmed by (HNMR)-H-1 and IR spectra.
Project supported by the Chinese Science Foundation and Shanxi Provincial Science Foundation.
Tetrahydrofolate (THF) coenzymes are involved in biochemical transfer of aone-carbon fragment at different oxidation levels. The study of THF models may providea valuable class of reagents for group transfer reactions...
This work was supported by the Science Foundation of Shanxi Province.
Four 1, 2, 3-trisubstituted imidazolinium iodides which were used as 5,10-^+CPh-THF model (7-10) at formic acid oxidation level were synthesized. The benzylidyne group (phenyl- substituted one carbon unit)transfer rea...