MULTIDRUG-RESISTANT

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Characterization and genomics analysis of phage PGX1 against multidrug-resistant enterotoxigenic E.coli with in vivo and in vitro efficacy assessment
《Animal Diseases》2025年第1期85-100,共16页Dayue Hu Ping Qian Dongyang Gao Xinxin Li Linkang Wang Hongyue Ji Shuang Wang Xiangmin Li 
supported by grants from the National Program on Key Research Project of China[2022YFD1800800,2021YFD1800300];the Yingzi Tech&Huazhong Agricultural University Intelligent Research Institute of Food Health[No.IRIFH202209,No.IRIFH202301];The National Program on Key Research Project of China,2022YFD1800800,Ping Qian,2021YFD1800300,Ping Qian,The Yingzi Tech&Huazhong Agricultural University Intelligent Research Institute of Food Health,IRIFH202209,Ping Qian,IRIFH202301,Ping Qian.
Enterotoxigenic E.coli is one of the bacterial pathogens contributing to the global resistance crisis in public health and animal husbandry.The problem of antibiotic resistance is becoming more and more serious,and ph...
关键词：Enterotoxigenic E.coli Multidrug-resistant bacteria Phage PGX1 
Urinary tract infections in kidney transplant patients admitted to hospital:A real-life experience
《World Journal of Transplantation》2025年第2期228-236,共9页Biagio Pinchera Rosa Carrano Elisa Schettino Alessia D'Agostino Emilia Trucillo Federica Cuccurullo Fabrizio Salemi Amerigo Piccione Ivan Gentile 
BACKGROUND Urinary tract infections(UTIs)in kidney transplant patients are a challenge.AIM To evaluate epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients in a univer...
关键词：Urinary tract infections Kidney transplant Multidrug-resistant germ Solid organ transplant recipient Empiric therapy 
Virulence Factors and Biofilm Formation in Multidrug-Resistant Metallo-β-Lactamase-Producing Clinical Strains of Pseudomonas aeruginosa
《Advances in Microbiology》2024年第12期589-604,共16页Adjaratou Traore Comoé Koffi Donatien Benie Abdoulaye Diarrassouba Wako-Tianwa Alice Tuo Oby Zéphirin Wayoro Adjéhi Dadié Nathalie Guessennd Mireille Dosso 
Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium, responsible for nosocomial infections, with a complex arsenal of pathogenicity. The aim of this study was to simultaneously characterize the potentia...
关键词：P. aeruginosa SEROGROUPS METALLO-Β-LACTAMASE VIRULENCE Biofilms 
Sunlenca■(Lenacapavir):A first-in-class,long-acting HIV-1 capsid inhibitor for treating highly multidrug-resistant HIV-1 infection
《Acta Pharmaceutica Sinica B》2024年第12期5512-5514,共3页Chunhua Ma Junbiao Chang Bin Yu 
support from the National Natural Science Foundation of China(Nos.22277110 and 82003585)and Tianjian Laboratory of Advanced Biomedical Sciences.
Lenacapavir,also known as GS-6207,under the brand name Sunlenca,was developed by Gilead Sciences Inc.It has been approved in the EU,Canada,and US for use alongside other antiretrovirals in adults with multidrug-resist...
关键词：Lenacapavir Capsid inhibitor HIV-1 infection HIV prevention Multidrug resistance Antiretroviral medication 
Erratum to“Detection of Patients at Risk of Multidrug-Resistant Enterobacteriaceae Infection Using Graph Neural Networks:A Retrospective Study”
《Health Data Science》2024年第1期25-26,共2页Racha Gouareb Alban Bornet Dimitrios Proios Sónia Gonçalves Pereira Douglas Teodoro 
In the Research Article“Detection of patients at risk of multidrugresistant Enterobacteriaceae infection using graph neural networks:A retrospective study”,Table 2 was incorrectly duplicated[1].TTe correct Table 1 i...
关键词：networks NEURAL 
Emergence of Multidrug-Resistant Proteus mirabilis Harboring both blaNDM-1 and cfr genes
《Biomedical and Environmental Sciences》2024年第10期1208-1212,共5页Meiqing Sun Xiuhong Yang Beibei Miao Jingyi Zhang Shuang Meng Zhe Feng Juan Li 
the National Key Research and Development Program of China[grant number 2021YFC2302002]for financial support.
Proteus mirabilis is abundant in soil and water,and although it is part of the normal human intestinal flora(along with Klebsiella species and Escherichia coli),it is known to cause serious infections in humans,with a...
关键词：LIS Proteus ant 
Cocrystal@protein-anchoring nanococktail for combinatorially treating multidrug-resistant cancer
《Acta Pharmaceutica Sinica B》2024年第10期4509-4525,共17页Jiahui Zou Xuyang Xing Chao Teng Qingling Zhao Wei He Xuri Wu Yuanzheng Xia 
supported by the National Natural Science Foundation of China(Nos.82073782 and 82241002,China);the Shanghai Science and Technology Committee(No.19430741500,China);National Key Research and Development Program of China(2018YFA0902000,China);the Key Laboratory of Modern Chinese Medicine Preparation of Ministry of Education of Jiangxi University of Traditional Chinese Medicine(zdsys-202103,China).
Multidrug resistance(MDR),the major mechanism by which various cancers develop specific resistance to therapeutic agents,has set up enormous obstacles to many forms of tumor chemotherapy.Traditional cocktail therapy a...
关键词：COCKTAIL MULTIDRUG-RESISTANT Co-delivery combined therapy Cytochrome C NANOCRYSTALS 
The cytochrome P4501A1(CYP1A1)inhibitor bergamottin enhances host tolerance to multidrug-resistant Vibrio vulnificus infection
《Chinese Journal of Traumatology》2024年第5期295-304,共10页Ruo-Bai Qiao Wei-Hong Dai Wei Li Xue Yang Dong-Mei He Rui Gao Yin-Qin Cui Ri-Xing Wang Xiao-Yuan Ma Fang-Jie Wang Hua-Ping Liang 
supported by the National Natural Science Foundation of China(grant number:82104247);Chongqing Talent Innovation Leading Plan(grant number:cstc2021ycjhbgzxm0340);Chongqing Doctor Express Project(grant number:CSTB2022BSXM-JCX0024);Hainan Clinical Medical Research Center Project(grant number:LCYX202205);Hainan Province Health Industry Research Project(grant number:22A200082).
Purpose:Vibrio vulnificus (V. Vulnificus) infection is characterized by rapid onset, aggressive progression, and challenging treatment. Bacterial resistance poses a significant challenge for clinical anti-infection tr...
关键词：Multidrug-resistant Vibrio vulnificus Bergamottin CYP1A1 inhibitors Infection tolerance 
Clinical analysis of adverse reactions in patients with multidrug-resistant and rifampicin-resistant pulmonary tuberculosis treated with delamanid-containing regimen
《China Medical Abstracts(Internal Medicine)》2024年第3期168-169,共2页GAO Mengqiu 
Objective To explore the characteristics of adverse drug reactions during the 24-week therapy with delamanid-containing regimen for patients with multidrug-resistant and rifampicin-resistant pulmonary tuberculosis(MDR...
关键词：TUBERCULOSIS REGIMEN PATIENTS 
Septic cardiomyopathy phenotype in the critically ill may depend on antimicrobial resistance
《Journal of Intensive Medicine》2024年第3期355-361,共7页Vasiliki Tsolaki Kyriaki Parisi George E.Zakynthinos Efrosini Gerovasileiou Nikitas Karavidas Vassileios Vazgiourakis Epaminondas Zakynthinos Demosthenes Makris 
the Institutional Review Board of the University Hospital of Larissa(approval number:55944/2022).
Background Sepsis is a life-threatening organ dysfunction,and septic cardiomyopathy(SCM)may complicate the course of the disease.Infection with multidrug-resistant(MDR)pathogens has been linked with worse outcomes.Thi...
关键词：Septic cardiomyopathy Multidrug-resistant pathogen Left ventricular failure Right ventricular dysfunction Left/right ventricular longitudinal strain Ventriculoarterial Coupling 
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