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In the article“Ameliorative effects of melatonin and zinc oxide nanoparticles treatment against adverse effects of busulfan induced infertility in male albino mice”(BIOCELL,2022,Vol.46,No.2,pp.535−545.doi:10.32604/b...
supported by grants from the Tianjin Health Science and Technology Project(No.TJWJ2022MS001);Clinical research project of Tianjin Society of Hematology and Regenerative Medicine(No.2022 TSHRM08004);Key Project of Tianjin Natural Science Foundation(No.20JCZDJC00410);CAMS Innovation Fund for Medical Sciences(No.2021-I2M-1-073);Haihe Laboratory of Cell Ecosystem Innovation Fund(No.22HHXBSS00034);National Natural Science Foundation of China(Nos.82070192,8230012348,and 82170217)
To the Editor:Allogeneic hemopoietic stem cell transplantation(allo-HSCT)represents the only long-term survival treatment choice for patients with myelodysplastic syndromes(MDS)and MDS/myeloproliferative neoplasm(MPN)...
National Natural Scientific Foundation of China;Grant/Award Number:81972975;National Human Diseases Animal Model Resource Center;National Science Foundation for Young Scientists of China;Grant/Award Number:81703170。
Background:Busulfan(BU)is an alkylating agent used as a conditioning agent prior to hematopoietic stem cell(HSC)transplantation as it is known to be cytotoxic to host hematopoietic stem and progenitor cells.The suscep...
This study was funded by Taif University Researchers Supporting Project No.TURSP-2020/222,Taif University,Taif,Saudi Arabia.
Testicular damage is one of the most hazardous effects as it’s associated with azoospermia.Busulfan(Bu)is a highly toxic chemotherapeutic drug that affects testis.Thirty male Swiss albino mice divided into six groups...
This study was supported by Shahid Beheshti University of Medical Sciences(grant number:184)。
Objective:To evaluate the protective effects of honey compound syrup on sperm count and testis tissue in rats.Methods:Thirty rats were randomly assigned to five groups.The control group received 1 mL normal saline wit...
supported by the National Natural Science Foundation of China(No.81770187);the National Key Research and Development Plan of China(No.2017YFA0104500).
Post-transplantation cyclophosphamide(PT-Cy)alone or in combination with other immunosuppressive drugs has emerged as a promising strategy in the setting of allogeneic hematopoietic stem cell transplantation.Improved ...
grants from the CAMS Initiative for Innovative Medicine(No.2017-I2M-B&R-06 and No.2017-I2M-3-007);the Major State Basic Research Project of China(No.2016YFA0101001 and No.2018YFC1003902);the National Natural Science Foundation of China(No.81701430);the China Postdoctoral Science Foundation(No.2017M611931).
Epididymitis can be caused by infectious and noninfectious etiological factors.While microbial infections are responsible for infectious epididymitis,the etiological factors contributing to noninfectious epididymitis ...
This study was supported by the National Natural Science Foundation of China(No.81571489,No.81671834,No.81671449 and No.81871110);the Frontier and Key Technology Innovation Special Foundation of Guangdong Province,China(No.2016B030230001);the Natural Science Foundation of Guangdong Province,China(No.2014A030310359,No.2016A030313229 and No.2015A030313013);the Science and Technology Planning Project of Guangdong Province,China(No.2016A020214004);the Health Care Collaborative Innovation Foundation Major Projects of Guangzhou City,Guangdong Province,China(No.201604020189);the Youth Teacher Training Project of Sun Yat-sen University(No.17ykpy68 and No.18ykpy09).
An ideal animal model of azoospermia would be a powerful tool for the evaluation of spermatogonial stem cell(SSC)transplantation.Busulfan has been commonly used to develop such a model,but 30%–87%of mice die when adm...
Objective To compare the efficacy,response and survival between high-dose melphalan(HDM)and cyclophosphamide+etoposide+busulfan(CVB)as the conditioning regimen in autologous stem cell transplantation(ASCT)for newly di...
Dear Editor, The merits of using quaff as an avian experimental model include high egg production, low maintenance cost, small body size, and short generation period (approximately 6-8 weeks). Indeed, these charact...