GLUCURONOSYLTRANSFERASE

作品数：17被引量：54H指数：4
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相关领域：医药卫生更多>>
相关作者：夏雪雁彭仁琇汪晖王君于皆平更多>>
相关机构：武汉大学更多>>
相关期刊：《World Journal of Gastrointestinal Surgery》《材料科学与工程（中英文A版）》《Asian Journal of Andrology》《广西医科大学学报》更多>>
相关基金：国家自然科学基金更多>>
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Targeting uridine diphosphate glucuronosyltransferase 1A1 in liver disease:Current research and future directions
《World Journal of Gastroenterology》2024年第39期4305-4307,共3页Seok-Chan Park Yu Ji Kim Jong-Won Kim 
The current letter to the editor pertains to the manuscript entitled'Uridine diphosphate glucuronosyltransferase 1A1 prevents the progression of liver injury'.Increased levels of uridine diphosphate glucuronosyltransf...
关键词：Uridine diphosphate glucuronosyltransferase 1A1 Liver injury Endoplasmic reticulum stress Oxidative stress Lipid metabolism disorders 
Uridine diphosphate glucuronosyltransferase 1A1 prevents the progression of liver injury被引量：1
《World Journal of Gastroenterology》2024年第9期1189-1212,共24页Jin-Lian Jiang Yi-Yang Zhou Wei-Wei Zhong Lin-Yan Luo Si-Ying Liu Xiao-Yu Xie Mao-Yuan Mu Zhi-Gang Jiang Yuan Xue Jian Zhang Yi-Huai He 
the Science and Technology Research Foundations of Guizhou Province,No.QKHJC-ZK(2022)YB642;Zunyi Science and Technology Plan Project,No.ZSKHHZ(2022)344,No.ZSKHHZ(2022)360,and No.ZYK160;Hubei Province Central Leading Local Science and Technology Development Special Project,No.2022BCE030;Changzhou Science and Technology Projects,No.CE20225054;Bijie City Science and Planning Bureau,No.BKH(2022)8.
BACKGROUND Uridine diphosphate glucuronosyltransferase 1A1(UGT1A1)plays a crucial role in metabolizing and detoxifying endogenous and exogenous substances.However,its contribution to the progression of liver damage re...
关键词：Uridine diphosphate glucuronosyltransferase 1A1 Liver injury progression Endoplasmic reticulum stress Oxidative stress Lipid metabolism disorders 
Postoperative jaundice related to UGT1A1 and ABCB11 gene mutations:A case report and literature review被引量：1
《World Journal of Clinical Cases》2023年第6期1393-1402,共10页Jin-Lian Jiang Xia Liu Zhong-Qin Pan Xiao-Ling Jiang Jun-Hua Shi Ya Chen Yu Yi Wei-Wei Zhong Kang-Yan Liu Yi-Huai He 
Supported by The Science and Technology Planning Projects of Guizhou Province and Zunyi City,No.QKHJCZK[2022]YB642,No.ZSKH·HZ(2022)344,No.gzwjkj2021-071,ZMC·YZ[2018]38,No.ZSKH·HZ[2021]58,and No.ZSKH·HZ[2021]60;The General Project of Hubei Province and Jingmen City,No.2021YFYB074.
BACKGROUND Patients with obstructive jaundice caused by intrahepatic bile duct stones can be effectively managed by surgery.However,some patients may develop postope-rative complications,liver failure,and other life-t...
关键词：CHOLESTASIS Intrahepatic bile duct stones Postoperative jaundice adenosine triphosphatebinding cassette subfamily B member 11 Uridine 5’-diphospho-glucuronosyltransferase 1A1 Case report 
Pharmacogenetics of the systemic treatment in advanced hepatocellular carcinoma被引量：10
《World Journal of Gastroenterology》2019年第29期3870-3896,共27页Elena De Mattia Erika Cecchin Michela Guardascione Luisa Foltran Tania Di Raimo Francesco Angelini Mario D’Andrea Giuseppe Toffoli 
the European Union’s Horizon 2020 Research and Innovation Programme,No.668353
Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. To date, most patients with HCC are diagnosed at an advanced tumor stage, excluding them from potentially curative therapies (i.e., re...
关键词：Hepatocellular carcinoma PHARMACOGENETICS Genetic markers SORAFENIB REGORAFENIB Immune CHECKPOINT inhibitors CYTOCHROMES UDP GLUCURONOSYLTRANSFERASE 1A 
Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in Chinese adult renal transplant recipients被引量：3
《Acta Pharmacologica Sinica》2017年第11期1566-1579,共14页Zi-cheng YU Pei-jun ZHOU Xiang-hui WANG Bressolle FRANCOISE Da XU Wei-xia ZHANG Bing CHEN 
We thank Prof Terol A and Prof Bataille B for advice and sup- port. This work was supported by the National Natural Science Foundation of China （No 30500626）.
Mycophenolate mofetil （MMF） is an important immunosuppressant used in renal transplantation, and mycophenolic acid （MPA） is the active component released from the ester prodrug MMF. The objective of this study was...
关键词：renal transplantation mycophenolate mofetil （MMF） mycophenolic acid （MPA） population pharmacokinetics uridine diphosphate glucuronosyltransferase （UGT） 
Correlation between UGT1A1 Polymorphism and Neonatal Hyperbilirubinemia of Neonates in Wuhan被引量：8
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第5期740-743,共4页刘伟 常立文 谢敏 李文斌 容志惠 吴莉 陈玲 
supported by the National Natural Science Foundation of China(No.81370099)
This study attempts to discuss the correlation between UGT1A1＊28 as uridine diphosphate glucuronosyltransferase gene promoter and coding region Gly71 Arg gene polymorphism with neonatal hyperbilirubinemia of neonates...
关键词：NEONATES gene polymorphism uridine diphosphate glucuronosyltransferase JAUNDICE UGT1A1＊28 Gly71Arg 
Genetic analysison the association between polymorphisms of UGT1A1and GST and neonatal hyperbilirubinemia
《广西医科大学学报》2016年第3期377-381,共5页Kun-Wen Deng Dan-Ni Zhong 
supported by the National Natural Science Foundation of China(No.81060055).
Objective:To investigate whether polymorphisms of uridine diphosphoglucuronate-glucuronosyltransferase 1A1(UGT1A1)c.211G>A and glutathione S transferases(GST)gene(GSTT1and GSTM1)are associated with neonatal hyperbilir...
关键词：Uridine diphosphate glucuronosyltransferase 1A1 Glutathione S-transferase POLYMORPHISM Hyperbil-irubinemia NEONATE 
Gum Arabic that is Enzymatically Modified with Arabidopsis Beta-Glucuronosyltransferase Can Make Smaller and more Stable Oil-in-Water Emulsions
《材料科学与工程（中英文A版）》2015年第1期69-77,共9页Adiphol Dilokpimol Naomi Geshi 
关键词：阿拉伯树胶 葡萄糖醛酸 酶促改性 拟南芥 稳定 阿拉伯半乳聚糖 水乳液 油包水乳状液 
Human liver stem/progenitor cells decrease serum bilirubin in hyperbilirubinemic Gunn rat
《World Journal of Gastroenterology》2014年第30期10553-10563,共11页Cédric Maerckx Tatiana Tondreau Silvia Berardis Jos van Pelt Mustapha Najimi Etienne Sokal 
Supported by Fonds pour la formation à la recherche dans l’industrie et dans l’agriculture
AIM: To test the ability of adult-derived human liver stem/progenitor cells (ADHLSC) from large scale cultures to conjugate bilirubin in vitro and in bilirubin conjugation deficient rat.
关键词：Liver stem/progenitor cells Gunn rat HEPATOCYTE in vitro and in situ differentiation Uridine diphosphate-glucuronosyltransferase 1A1 
Polymorphisms of UGT1A7 and XRCC1 are Associated with an Increased Risk of Hepatocellular Carcinoma in Northeast China被引量：3
《Chinese Journal of Cancer Research》2010年第4期260-266,共7页Zhi-fang Jia Hong-ying Su Xue-lian Li Xin Xu Zhi-hua Yin Peng Guan Bao-sen Zhou 
supported by the grant from Department of Education of Liaoning Province, China (No. 2008S232)
Objective： Hepatocellular carcinoma （HCC） is a complex disease which associates with both environmental and genetic factors. The purpose of this study was to investigate whether the genetic polymorphisms of UDP-glu...
关键词：Hepatocellular carcinoma （UDP）-glucuronosyltransferase 1A7（UGT1A7） X-ray repair crosscomplementing group 1（XRCC1） Risk factors Genetic polymorphism 
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