supported by the National Key Research and Development Program of China(2021YFC2701100);the National Natural Science Foundation of China(81930036,32293230 and 8215008);the Commission for Science and Technology of Shanghai Municipality(20JC1418500 and 20ZR1404800);Project supported by Shanghai Municipal Science and Technology Major Project。
Heparan sulfate proteoglycan 2(HSPG2)gene encodes the matrix protein Perlecan,and genetic inactivation of this gene creates mice that are embryonic lethal with severe neural tube defects(NTDs).We discovered rare genet...
supported by the National Key Basic Research Program of China(2012CB966500,2013CB-967100);the National Natural Science Foundation of China(31201112)
The androgenetic embyronic stem (aES) cells are useful models in studying the effects of imprinted genes on pluripotency maintaining and embryo development. The expression patterns of imprinted genes are significantly...
We had already produced androgenetic haploid of Xenopus laevis in previous expriments, but could not obtain the complete metamorphosis. So far it has not been known that in anuran amphibia, fertilized egg with only pa...