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作品数：9被引量：58H指数：3
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Risk factors related to significant hepatic inflammation in patients with acute drug-induced liver injury
《iLIVER》2024年第2期35-42,共8页Yu-Ting Xiong Jian-Fei Wang Le Li Zhi-Fang Bai Yan Liu Ang Huang Ke-Xin Wang Yiming Fu Wucai Yang Chang Guo Mengwen He Wen-Chang Wang Chun-Yan Wang Dong Ji 
supported by the Capital's Funds for Health Improvement and Research(No.2024-2-5068);the Youth Independent Innovation Project of PLA General Hospital(No.22QNCZ023);Beijing Natural Science Foundation(No.7242030);Capital Clinical Characteristic Application Research(No.Z181100001718034).
Background and aims:Currently,research on biopsy-proven acute drug-induced liver injury(DILI)remains limited.This study aimed to identify clinical characteristics and risk factors for significant hepatic inflammation ...
关键词：Acute drug-induced liver injury Liver biopsy Hepatic inflammation FEMALE AUTOIMMUNITY CHRONICITY 
Impact of Chronicity on Outcomes Following Post-Hospital Residential Brain Injury Rehabilitation: Application of Multivariate Statistics and Rasch Analysis被引量：2
《Open Journal of Statistics》2017年第2期254-263,共10页Frank D. Lewis Gordon J. Horn Robert Russell 
This study evaluated the impact of chronicity (onset of injury to admission in-terval) on three domains of functional outcomes for a large group of traumatic brain injured (TBI) survivors. Subjects included 528 TBI ad...
关键词：TBI MULTIVARIATE Analysis CHRONICITY Outcome Post-Hospital REHABILITATION MPAI-4 Raschanalysis Functional Assessment 
Effective intrahepatic CD8＋ T-cell immune responses are induced by low but not high numbers of antigen-expressing hepatocytes被引量：1
《Cellular & Molecular Immunology》2016年第6期805-815,共11页Aaron Ochel Marcin Cebula Mathias Riehn Upneet Hillebrand Christoph Lipps Reinhold Schirmbeck Hansjorg Hauser Dagmar Wirth 
Liver infections with hepatotropic viruses, such as hepatitis B virus and hepatitis C virus are accompanied by viral persistence and immune failure. CD8＋ T cells are crucial mediators of the intrahepatic antiviral im...
关键词：antigen load CHRONICITY immune modulation T-cell exhaustion 
Establishment of chronic hepatitis C virus infection:Translational evasion of oxidative defence
《World Journal of Gastroenterology》2014年第11期2785-2800,共16页Shiu-Wan Chan 
Supported by The work quoted from my laboratory was supported by a Medical Research Council(United Kingdom)grant
Hepatitis C virus(HCV)causes a clinically important disease affecting 3%of the world population.HCV is a single-stranded,positive-sense RNA virus belonging to the genus Hepacivirus within the Flaviviridae family.The v...
关键词：Hepatitis C virus Oxidative stress Hydrogen peroxide Translation Internal ribosome entry site CHRONICITY Persistence 
COMPLEX ISOCHRONICITY OF A SIXTH DEGREE SYSTEM
《Annals of Differential Equations》2007年第3期352-357,共6页Wang Qinlong Song Shugang Liu Yirong 
the Fundation of Hubei Education Bureau(2003A008).
In this paper, we discuss the complex isochronicity of a sixth degree polynomial system. We first adopt a new algorithm to find necessary conditions for complex isochronicity, then prove the sufficient conditions usin...
关键词：complex isochronicity sixth degree system 
The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection被引量：23
《World Journal of Gastroenterology》2007年第1期104-124,共21页Stephan Menne Paul J Cote 
Supported by contract N01-AI-05399 to the College of Veterinary Medicine, Cornell University from the National Institute of Allergy and Infectious Diseases. PC and SM also have been supported by contract N01-AI-95390 to the Georgetown University Medical Center, Georgetown University from the National Institute of Allergy and Infectious Diseases
This review describes the woodchuck and the woodchuck hepatitis virus (WHV) as an animal model for pathogenesis and therapy of chronic hepatitis B virus (HBV) infection and disease in humans. The establishment of wood...
关键词：WOODCHUCK Woodchuck hepatitis virus Hepatitis B virus Neonatalacquired infection Adult-acquired infection Resolution CHRONICITY Humoral immune response Cellular immune response Antiviraltherapy Immunotherapy Combination therapy Hepatocellular carcinoma 
Aggressive treatment of acute anal fissure with 0.5% nifedipine ointment prevents its evolution to chronicity被引量：1
《World Journal of Gastroenterology》2006年第38期6203-6206,共4页Panagiotis Katsinelos Jannis Kountouras George Paroutoglou Athanasios Beltsis Grigoris Chatzimavroudis Christos Zavos Taxiarchis Katsinelos Basilis Papaziogas 
AIM： To investigate the efficacy of topical application of 0.5% nifedipine ointment in healing acute anal tissue and preventing its progress to chronicity. METHODS： Thirty-one patients （10 males, 21 females） with ...
关键词：Acute anal fissure NIFEDIPINE Calcium channel blockers Topical treatment 
Immunoregulatory Role of B7-H1 in Chronicity of Inflammatory Responses被引量：25
《Cellular & Molecular Immunology》2006年第3期179-187,共9页Haidong Dong Xianming Chen 
Pathogenesis of most chronic human diseases, including chronic infections, autoimmune diseases and cancers, often involves a persistent, unresolved inflammatory response. The molecular mechanisms that determine the co...
关键词：B7-HI immune response INFLAMMATION chronization INFECTION TUMOR 
Helicobacterpylori virulence factors in duodenal ulceration:A primary cause or a secondary infection causing chronicity被引量：6
《World Journal of Gastroenterology》2006年第1期6-9,共4页FrankI Tovey Michael Hobsley John Holton 
Reports from countries with a high prevalence of Helicobacter pylori （H pylori） infection do not show a proportionately high prevalence of duodenal ulceration, suggesting the possibility that H pylori cannot be a pr...
关键词：Duodenal ulceration Helicobacter pylorivirulence factors 
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