ELECTROMOTILITY

作品数：7被引量：6H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Journal of Otology》《Neural Regeneration Research》《Neuroscience Bulletin》更多>>
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The role of Rho GTPase family in cochlear hair cells and hearing被引量：2
《Neural Regeneration Research》2023年第10期2167-2172,共6页Yu-Bei Dai Xiang Gao Dong Liu Jie Gong 
supported by the Natural Science Foundation of Jiangsu Province,No.BK20221377(to JG);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China,No.22KJB180023(to JG)。
Rho GTPases are essential regulators of the actin cytoskeleton.They are involved in various physiological and biochemical processes such as the regulation of cytoskeleton dynamics,development,proliferation,survival,an...
关键词：actin assembly auditory sensory neurons cell polarity cell proliferation ELECTROMOTILITY hair cell hearing loss MORPHOGENESIS Rho GTPases STEREOCILIA 
Prestin-Mediated Frequency Selectivity Does not Cover Ultrahigh Frequencies in Mice被引量：1
《Neuroscience Bulletin》2022年第7期769-784,共16页Jie Li Shuang Liu Chenmeng Song Tong Zhu Zhikai Zhao Wenzhi Sun Yi Wang Lei Song Wei Xiong 
This work was supported by the National Natural Science Foundation of China(31522025,31571080,81873703,81770995,and 31861163003);Beijing Munic ipal Science and Technology Commission(Z181100001518001);a startup fund from the Tsinghua-Peking Centerfor Life Sciences to W.X.W.X.is a CIBR cooperative investigator(2020-NKX-XM-04)funded by the Open Collaborative Research Program of Chinese Institute for Brain Research;National Key Research and Development Project(2018YFC1003003);The Postdoctoral International Exchange Program(Talent-Introduction Program);the Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases(14DZ2260300).
In mammals,the piezoelectric protein,Prestin,endows the outer hair cells(OHCs)with electromotility(eM),which confers the capacity to change cellular length in response to alterations in membrane potential.Together wit...
关键词：PRESTIN PIEZO2 Ultrahigh-frequency hearing ELECTROMOTILITY Outer hair cells 
Quantitative Relations between Outer Hair Cell Electromotility and Nonlinear Capacitance
《Journal of Otology》2012年第1期45-53,共9页WANG Xiang GUO Wei-Wei YANG Shi-Ming 
The electrically evoked somatic motility of outer hair cells （OHC）, briefly termed OHC electromotility, plays a crucial role in cochlear amplification that underlies the remarkably high sensitivity and frequency sel...
关键词：Outer hair cell ELECTROMOTILITY Nonlinear Capacitance PRESTIN COCHLEA 
Prestin forms tetramer with each subunit being mechanically independent
《Journal of Otology》2009年第2期86-97,共12页WANG Xiang 1, GUO Wei-wei 2, HE David Zhi-Zhou1, YANG Shi-Ming 2 1 Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE 68178, USA 2 Institute of Otolaryngology, Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Beijing 100853 
supported by an NIDCD grant (R01DC004696) to DH;by National Natural Science Foundation of China grants 30871398, 30730040 and 30628030 to SY and DH;supported bygrant number G20RR024001 from the National Center for Research Resources
Prestin is the motor protein of cochlear outer hair cells （OHCs）. It is able to perform rapid and reciprocal electromechanical conversion that underlies OHC electromotility. Due to the inadequate size of a single pr...
关键词：PRESTIN OLIGOMER outer hair cells ELECTROMOTILITY nonlinear capacitance GERBIL 
Distribution of Prestin on Outer Hair Cell Basolateral Surface被引量：3
《Journal of Otology》2008年第2期92-97,共6页YU Ning1,2, ZHAI Suo-qiang1, YANG Shi-ming1, HAN Dong-yi1, ZHAO Hong-bo2, 1 Department of Otolaryngology & Institute of Otolaryngology, CPLA General Hospital, BJ, 100853 2 Department of Surgery-Otolaryngology, University of Kentucky Medical Center, Lexington, KY 40536-0293 
supported by NIH (NIDCD DC 05989);NSFC (30600700, 30772413)
Prestin has been identified as a motor protein responsible for outer hair cell (OHC) electromotility and is expressed on the OHC surface. Previous studies revealed that OHC electromotility and its associated nonlinear...
关键词：plasma mebrane outer hair cell electromotility COCHLEA active mechanics di-8-ANEPPS 
An Overview of Electrically Evoked Otoacoustic Emissions in the Mammalian Cochlea
《Journal of Otology》2006年第1期45-50,共6页Alfred L. Nuttall 
Alternating currents injected into the cochlea are able to evoke outer hair cell-mediated basilar membrane motion, thus give rise to production of otoacoustic emissions. This electrically evoked otoacoustic emission(E...
关键词：COCHLEA out hair cell ELECTROMOTILITY otoacoustic emissions electrical stimulation 
Direct current pulse elicits basilar membrane vibration in guinea pigs
《Journal of Medical Colleges of PLA(China)》2000年第3期231-235,共5页郭梦和 任田英 Alfred L Nuttall 
Objective:To study the electromotility of the basilar membrane (BM) of guinea pigs in vivo. Methods :A pair of platinum-iridium wire electrodes were deposited into the holes drilled into the scala vestibuli and scala ...
关键词：COCHLEA VIBRATION BASILAR MEMBRANE ELECTROMOTILITY 
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