C-PEPTIDE

作品数:28被引量:54H指数:5
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相关作者:张梦张维真张爱华陈颖黄松明更多>>
相关机构:南京医科大学第二附属医院徐州市中心医院中国科学院上海生命科学研究院更多>>
相关期刊:《Chinese Medical Journal》《World Journal of Diabetes》《World Journal of Pediatrics》《Chinese Medical Sciences Journal》更多>>
相关基金:国家自然科学基金更多>>
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Two Years of Modified Protocol with Cyclosporin A for Treatment of Acute Insulin Resistance Induced by Anti-Glutamic Acid Decarboxylase (GAD) Antibodies in Obese Type II Diabetics
《Journal of Diabetes Mellitus》2025年第1期52-58,共7页Kamel El-Reshaid Shaikha Al-Bader 
Background: Diabetes mellitus (DM) is a disease characterized by hyperglycemia due to (a) insulin-insufficiency (type I DM), or (b) impaired glucose cell-entry (insulin resistance) due to the downregulation of insulin...
关键词:Anti-GAD Antibodies C-PEPTIDE Cyclosporin A Diabetes Mellitus HYPERGLYCEMIA Insulin Resistance Therapy 
Distinguishing exocrine pancreas disease-associated diabetes from type 2 diabetes based on anthropometric and metabolic parameters
《World Journal of Diabetes》2025年第2期28-37,共10页Anna Juza Lilianna Kołodziej-Spirodek Krzysztof Gutkowski Mariusz Partyka Mariusz Dąbrowski 
BACKGROUND Adult-onset diabetes is most often considered to be type 2 diabetes.However,other types of diabetes can develop in adults,including exocrine pancreas diseaseassociated diabetes,also called type 3c diabetes....
关键词:Pancreatic cancer Chronic pancreatitis DIABETES ADRENOMEDULLIN ADIPONECTIN Insulin C-PEPTIDE 
Impact of setting distinct target blood glucose levels on endogenous insulin suppression and pharmacodynamics of insulin preparations
《World Journal of Diabetes》2025年第2期47-54,共8页Hui Liu Ting Li Xin-Lei Chen Hong-Ling Yu Ye-Rong Yu 
This retrospective analysis incorporated data from two clinical trials(CTR20220854 and CTR20222843);sponsored by Chongqing Chenan Biopharmaceutical Co.,Ltd.and Jiangsu Hengrui Pharmaceuticals Co.,Ltd.However,these sponsors did not partake in the study design,data interpretation,or manuscript preparation.
BACKGROUND Insulin therapy plays a crucial role in managing diabetes.Regulatory guidelines mandate assessing the pharmacokinetics(PK)and pharmacodynamics(PD)of new insulin formulations with euglycemic clamp techniques...
关键词:Euglycemic clamp Target glucose setting Healthy subject C-PEPTIDE PHARMACODYNAMICS Endogenous insulin secretion 
Current perspectives and the future of disease-modifying therapies in type 1 diabetes
《World Journal of Diabetes》2025年第1期12-21,共10页Sunetra Mondal Joseph M Pappachan 
Use of immunomodulating agents to prevent the progression of autoimmuneβ-cell damage leading to type 1 diabetes mellitus(T1DM)is an interesting area for research.These include non-specific anti-inflammatory agents,im...
关键词:Teplizumab Type 1 diabetes mellitus Disease modifying therapy β-cell function C-PEPTIDE IMMUNOTHERAPY 
Future clinical prospects of C-peptide testing in the early diagnosis of gestational diabetes
《World Journal of Experimental Medicine》2024年第1期13-21,共9页Charalampos Milionis Ioannis Ilias Anastasia Lekkou Evangelia Venaki Eftychia Koukkou 
Gestational diabetes is typically diagnosed in the late second or third trimester of pregnancy.It is one of the most common metabolic disorders among expectant mothers,with potential serious short-and long-term compli...
关键词:C-PEPTIDE Gestational diabetes Secondary prevention PREGNANCY Clinical laboratory techniques 
25-Hydroxyvitamin D Is Associated with Islet Homeostasis in Type-2 Diabetic Patients with Abdominal Obesity
《Current Medical Science》2023年第5期919-926,共8页Qing LI Wen ZHANG Bing HAN Yu-ying WANG Heng WAN Min ZHANG Ning-jian WANG Ying-li LU 
supported by the National Natural Science Foundation of China(No.82120108008,No.91857117);the Project of Biobank(No.YBKA201909)from Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine;a grant from Shanghai Jiaotong University School of Medicine(No.19XJ11007).
Objective Isletαcells input is essential for insulin secretion fromβcells.The present study aims to investigate the association between 25-hydroxyvitamin D[25(OH)D]and islet function homeostasis in type-2 diabetes(T...
关键词:25-hydroxyvitamin D GLUCAGON C-PEPTIDE isletαcells isletβcells type-2 diabetes 
Assessment of long-term graft function following total pancreatectomy and autologous islet transplantation:the Leicester experience
《Hepatobiliary Surgery and Nutrition》2023年第5期682-691,I0016,共11页Cristina A.Pollard Wen Yuan Chung Giuseppe Garcea Ashley R.Dennison 
Background:Total pancreatectomy and islet autotransplantation(TPIAT)is a recognised treatment for chronic pancreatitis(CP)with the potential to mitigate or prevent pancreatogenic diabetes.We present our 10-year follow...
关键词:Islet autotransplantation(IAT) chronic pancreatitis(CP) C-PEPTIDE 
Role of C-Peptide in Relation to Levels of Anti-GAD and Islet Cell Antibodies in Characterizing Types of Diabetes in the Young, in Eastern India
《Journal of Diabetes Mellitus》2022年第1期1-11,共11页Sidhartha Das Dipanweeta Routray Manoranjan Behera Saroj Kumar Tripathy 
Background: Measuring fasting C-peptide (FCP) and antibodies against Glutamic acid decarboxylase (GADA) and Islet cell antibodies (ICA) are not so commonly explored in children and young adults. Objectives: To assess ...
关键词:C-PEPTIDE Anti-Glutamic Acid Decarboxylase Antibodies (GADA) Islet Cell Antibodies (ICA) ROC Analysis Type 1 DM Type 2 DM 
Urinary C-peptide Creatinine Ratio and Its Correlation with Parameters of Metabolic Syndrome
《Journal of Endocrinology Research》2021年第2期1-9,共9页Manoj Gedam Dipti Sarma Bipul Choudhury 
To assess the correlation between urinary C peptide creatinine ratio with serum C peptide,serum insulin and its correlation with clinical and biochemical parameters of metabolic syndrome.A total of 100 subjects more t...
关键词:Metabolic syndrome Insulin resistance Body mass index Type 2 diabetes mellitus 
Research Progress of C-Peptide and Its Physiological Function
《International Journal of Clinical Medicine》2020年第5期207-215,共9页Rong Zeng Shuyu Huang Shibo Liao 
As a product in the process of insulin synthesis, C-peptide’s physiological function is still not very clear. Recent studies have shown that C-peptide has many potential cell targets and has biological effects on a v...
关键词:C-PEPTIDE PHYSIOLOGICAL FUNCTIONS REVIEW 
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