BUFADIENOLIDE

作品数：8被引量：14H指数：3
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相关领域：化学工程医药卫生更多>>
相关期刊：《Chinese Journal of Cancer Research》《Chinese Herbal Medicines》《Chinese Journal of Natural Medicines》《Chemical Research in Chinese Universities》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划更多>>
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Cinobufagin, a bufadienolide from traditional Chinese medicine Bufo bufo gargarizans CANTOR, inhibits PC3 cell growth in vitro and in vivo被引量：5
《Journal of Traditional Chinese Medical Sciences》2019年第2期175-183,共9页Tianli Niu Liye Zhao Xuyao Lin Yangkai Cai Shuhui Chen Mingkai Wang Li Zhou Hongyang Ding Xiaohan Yu Guozheng Qin 
This study was supported by the National Natural Science Foundation of China(81260540).
Objective:To explore the effects of cinobufagin (CBF),an active component of toad venom (Bufo bufo gargarizans CANTOR),on the proliferation and apoptosis of PC3 human prostate cancer cells in vitro and preliminarily i...
关键词：Prostate cancer CINOBUFAGIN CELL proliferation CELL apoptosis MCL-1 
Chemical constituents from Kalanchoe hybrida and their cytotoxicity
《Chinese Herbal Medicines》2018年第2期231-235,共5页Ping-chung Kuo Hsin-yi Hung Yu-ren Liao Yu-yi Chan Tian-shung Wu 
the Ministry of Science and Technology, Taiwan, China for the financial support;supported in part by Taiwan Department of Health Clinical Trial and Research Center of Excellence (Grant No: NSC 92-2323-B-006-002)
Objective：Kalanchoe hybrida（Crassulaceae）is naturalized throughout all the island of Taiwan in China.The preliminary bioassay-guided fractionation of the crude extract of K.hybrida exhibited that the chloroform and...
关键词：BUFADIENOLIDE CRASSULACEAE CYTOTOXICITY flavonol glycoside Kalanchoe hybrida（J. D. Hooker）Vilmorin 
A new bufadienolide with cytotoxic activity from the Chinese traditional drug Ch'an Su被引量：2
《Chinese Journal of Natural Medicines》2014年第8期623-627,共5页XU Ran XIE Hai-Qin DENG Lu-Lu ZHANG Jian-Xin YANG Fu-Mei LIU Jian-Hua HAO Xiao-Jiang ZHANG Yuan-Hu 
supported by the National Natural Science Foundation of China(No.30960497);the Science and Technology Commission of China(No.2012CB722601);the Science and Technology Department of Guizhou Province(No.QKHZYZ[2011]5085)
AIM: To study the bufadienolides in the Chinese traditional drug "Ch'an Su" and their cytotoxic activity. METHOD: Various chromatographic techniques were used to isolate the constituents, and their structures were elu...
关键词：＂Ch＇an Su＂ New bufadienolide Bufalin 3fi-acrylic ester Cytotoxicity 
New cytotoxic C-3 dehydrated bufadienolides from the venom of Bufo bufo gargarizans被引量：2
《Chinese Chemical Letters》2014年第7期1104-1106,共3页Hai-Yan Tian Peng-Wei Zhang Jun-Shan Liu Dong-Mei Zhang Xiao-Qi Zhang Ren-Wang Jiang Wen-Cai Ye 
supported by National Natural Science Foundation of China(No.81102518);Postdoctoral Granted Financial Support(No.20110490915);the Guangdong High Level Talent Scheme(R.W.J.)
Three new C-3 dehydrated bufadienolides were isolated from the venom of Bufo bufo gargarizans. Their structures were elucidated as 5β,12β-12,14-dihydroxy-11-oxobufa-3,20,22-trienolide （1）, 5β,12β- 12,14-dihydrox...
关键词：Toad venom Bufo bufo gargarizans 3-Dehydrated bufadienolide Cytotoxicity 
Simultaneous Determination of Bufadienolides and Qualitative Evaluation for Venenum Bufonis by High Performance Liquid Chromatography
《Chemical Research in Chinese Universities》2009年第6期801-806,共6页HUANG Hao LIANG Ming-jin LUO Heng ZHANG Wei-dong 
Supported by the National Basic Researeh Program of China(No.2007CB507400);the National High Technology Research and Development Program(No.2006AA02Z338);Program for Changjiang Scholars and Innovative Research Team in Universities of China(PCSIRT);Partly Supported by the Scientific Foundation of Shanghai City,China(Nos.05DZ19733,06DZ19717,06DZ19005)
A high performance liquid chromatographic method was used for the simultaneous identification and qualitative evaluation of 12 bufadienolides（resibufogenin, einobufagin, cinobufaginol, arenobufagin, bufalin, bufotali...
关键词：BUFADIENOLIDE High performance liquid chromatography Simultaneous analysis Qualitative evaluation Venenum Bufonis 
A new cytotoxic bufadienolide from Chinese medicine Chansu被引量：5
《Chinese Chemical Letters》2008年第12期1445-1446,共2页Xiu Lan Xin Rong Lan Jian Huang Xiao Jie Wang Jing Ming Jia 
PHR (IHLB) the Beijing Ministry of Education for financial support.
A new cytotoxic bufadienolide was isolated from the traditional Chinese medicine-Chansu. The structure of new compound was elucidated on the basis of spectral methods including 2D NMR. And it showed strong in vitro cy...
关键词：BUFADIENOLIDE STEROID CYTOTOXICITY Chansu 
One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans被引量：3
《Chinese Chemical Letters》2008年第3期299-301,共3页Li Qiao Yu Zhi Zhou Huan Chen Jia Qing Cao Yue Hu Pei 
Cunninghamella elegans has been employed for the biotransformation of cinobufagin （1） to afford one metabolites. The structure of the transformation product has been characterized as 7β,12β-dihydroxylcinobufagin ...
关键词：BIOTRANSFORMATION CINOBUFAGIN 7β 12β-Dihydroxylcinobufagin Cunninghamella elegans 
ISOLATION AND IDENTIFICATION OF CYTOTOXIC COMPONENTS FROM BRYOPHYLLUM PINNATUM被引量：1
《Chinese Journal of Cancer Research》1992年第4期4-6,共3页严秀珍 李国雄 Yamagishi Takashi 
A potent cytotoxic bufadienolide orthoacetate has been Isolated from Bryophyllum pinnatum. Baaed on spectral study methods, its structure was identified as bersaldegenin 1,3, 5-orthoacetate.
关键词：bryophyllum pinnatum bufadienolide orthoacetate bersaldegenin 1 3 5- orthoacetate CYTOTOXICITY antitumor activity. 
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