financially supported by the Fundamental Research Funds for the Central Universities at Zhejiang University,Hangzhou,China(Grant No.2016XZZX001-09)
Phospholipids are a major kind of lipids in rice grains and have fundamental nutritional andfunctional benefits to the plant. Their lyso forms (lysophospholipids, LPLs) often form inclusion complexeswith amylose or ...
Lysophospholipids are small,membrane-derived lipids that act through a growing family of G protein-coupled receptors(GPCRs)that account for around 40% of the known lipid GPCRs.They comprise a range of distinct chemica...
Previous studies on lysophosphatidic acid (LPA) and sphingosine 1-phosphate (SIP) using various approaches have shown that both the molecules can act as intercellular signaling molecules. The discovery of the Edg ...
Project supported by grants from the Health Research Fund and European Commission(F1S-FEDER 04/0843 and 06/0813);Departmcnt of Education and Scicncc of Spain(SAF2005一04293);"Mutua Madrilena"Medical Research Foundation (FMM);'la Caixa" Foundation (BMOS一30-0);Consuelo GAlATE was supported by the "namon y Cajal" Program from the Department of Education and Science of Spain.
Aim: To investigate whether a similar process mediates cytotoxicity of 1-O- octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET- 18-OCH3, edelfosine) in both yeasts and human tumor cells. Methods: A modified ver...