FIBROGENESIS

作品数：46被引量：605H指数：15
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相关领域：医药卫生更多>>
相关作者：陈志南边惠洁李浩吴佼更多>>
相关机构：第四军医大学同济大学上海中医药大学更多>>
相关期刊：《Journal of Bio-X Research》《World Journal of Gastroenterology》《肝脏》《Current Medical Science》更多>>
相关基金：国家自然科学基金河北省自然科学基金上海市教育委员会重点学科基金广西壮族自治区自然科学基金更多>>
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Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis被引量：2
《Asian Pacific Journal of Tropical Medicine》2017年第5期423-432,共10页Naglaa M.El-Lakkany Walaa H.El-Maadawy Sayed H.Seif el-Din Olfat A.Hammam Salwa H.Mohamed Shahira M.Ezzat Marwa M.Safar Samira Saleh 
supported by Theodore Bilharz Research Institute(grant number:ID-MS-99/A,2012,PI:Naglaa El-Lakkany)
Objective:To investigate the antifibrotic role of rosmarinic acid(RA),a natural polyphenolic compound,on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods:The impact of RA on stellate cell line...
关键词：Hepatic fibrosis Hepatic stellate cells Rosmarinic acid APOPTOSIS PROLIFERATION Profibrogenic markers 
Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation被引量：6
《World Journal of Gastroenterology》2014年第36期13088-13104,共17页Devanshi Seth Alastair Duly Paul C Kuo Geoffrey W McCaughan Paul S Haber 
Supported by Philanthropic Anonymous Source;the University of Sydney Bridging Support Grant,in part for Honours Project;Supported by the National Health and Medical Research Council,No.NHMRC Practitioner Research Fellowship for PH support
AIM: To investigate over-expression of Osteopontin (OPN) pathway expression and mechanisms of action in human alcoholic liver disease (ALD), in vivo and in vitro acute alcohol models.
关键词：Hepatic stellate cells Liver cirrhosis PLASMIN STEATOSIS FIBROGENESIS Transforming growth factor β Osteopontin isoform 
Emodin protects rat liver from CCl_4-induced fibrogenesis via inhibition of hepatic stellate cells activation被引量：22
《World Journal of Gastroenterology》2009年第38期4753-4762,共10页Miao-Xian Dong Yan Jia Ying-Bo Zhang Cheng-Chong Li Yu-Tao Geng Li Zhou Xue-Yan Li Ji-Cheng Liu Ying-Cai Niu 
Supported by National Natural Science Foundation of China,No.30873396;National Science Foundation for Post-doctoral Scientists of China,No.20080430140;Qiqihar Foundation for Development of Science and Technology,China,No.05090
AIM： To investigate the role of emodin in protecting the liver against fibrogenesis caused by carbon tetrachloride （CCh） in rats and to further explore the underlying mechanisms. METHODS： Rat models of experimenta...
关键词：EMODIN Hepatic fibrosis Transforming growth factor-β1 SMAD4 Hepatic stellate cell α-smooth muscle actin 
Relationship between focal adhesion kinase and hepatic stellate cell proliferation during rat hepatic fibrogenesis被引量：19
《World Journal of Gastroenterology》2004年第20期3001-3005,共5页Hui-QingJiang Xiao-LanZhang LiLiu Chang-ChunYang 
Supported by the Natural Science Foundation of Hebei Province,No.301361
AIM: To investigate the dynamic expression of focal adhesion kinase (FAK) protein and FAK mRNA in fibrotic rat liver tissue, and the relationship between FAK and hepatic stellate cell (HSC) proliferation.METHODS: Rat ...
关键词：支持激酶 肝星形细胞 分芽增殖期间 老鼠 肝纤维化 
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