Background : To study the relationships among emodin, synovial fibroblasts (FLSs), and macrophages (STMs) to provide guidance for the use of emodin in rheumatoid arthritis (RA) treatment. Methods : RA clinical samples...
National Natural Science Foundation of China(Nos.82030113,82130108,and 82204717);China Postdoctoral Science Foundation(Nos.BX20220069 and 2021M700864).
The proper differentiation and reorganization of the intestinal epithelial cell population is critical to mucosal regeneration post injury.Label retaining cells(LRCs)expressing SRY-box transcription factor 9(SOX9)prom...
Following the publication,concerns have been raised about a number of figures in this article.The transwell invasion assays shown in Fig.2A were strikingly similar to data appearing in different form in other articles...
supported by the National Natural Science Foundation of China(No.21971212);the Key Project of Innovation Research 2035 Pilot Plan of Southwest University(SWU-XDZD22007).
A type of unique azole-hybridized acylhydrazonyl aloe emodins(AAEs)were developed as new antibacterial agents for combating bacterial infections.Some target AAEs showed strong antibacterial activities,especially,tetra...
Fujian Major Research Grants for Young and Middle-aged Health Professionals(No.2021ZQNZD012,Research and Development of Anti-Keratitis Protein Drug Sgp130);National Natural Science Foundation of China(No.81774369,Study on Mechanism of Yijing Decoction in Preventing Microvascular Damage of Early Diabetic Retinopathy based on MMPs/TIMPs)。
OBJECTIVE:To investigate the effects of emodin on alkali burn-induced corneal inflammation and neovascularization.METHODS:The ability of emodin to target vascular endothelial growth factor receptor 2(VEGFR2)was predic...
supported by the National Natural Science Foundation of China(22088102,21872016,and 22172018);the Fundamental Research Funds for the Central Universities of China(DUT20LAB307)
Solar-driven photoreduction of CO_(2)to value-added fuels such as CO,CH_(4),and CH_(3)OH is a promising approach for alleviating the greenhouse effect.Transition-metal-complex molecular catalysts exhibit high catalyti...
Supported by the Chinese Medicine Research Project of Hubei Provincial Health Commission(No.ZY2019Q024);Scientific Research Project of Wuhan Municipal Health Commission(No.WX20B11);Scientific Research Project of Wuhan Municipal Health Commission(No.WZ20C01)。
Objective To investigate the effect of emodin on high glucose(HG)-induced podocyte apoptosis and whether the potential anti-apoptotic mechanism of emodin is related to induction of adenosine-monophosphate-activated pr...
supported by the Hainan Association’s Innovation Project for Science and Technology Young Talents(QCXM201907);the Scientific Research Foundation for Hainan University(KYQD(ZR)20037);the Innovative Research Projects for Graduate Students in Hainan Province(Qhys2021-163)。
This study was to determine the effects of dietary emodin(ED)on the intestinal mucosal barrier,nuclear factor kappa-B(NF-κB)pathways,and gut microbial flora in lipopolysaccharide(LPS)-induced piglets.Twenty-four wean...
supported by Guangdong Science and Technology Program(No.2015B020211006);the Technology Project of Guangzhou City in China(No.201604020137);Shenzhen Foundation of Science and Technology(No.JCYJ20190814112205770);Research Foundation of Shenzhen Hospital of Southern Medical University(No.PY2021YM03);the Project of Traditional Chinese Medicine Bureau of Guangdong Province(No.20221273).
Background:As accelerators and products of the progression of chronic kidney disease(CKD),advanced oxidation protein products(AOPPs)affect the function of the liver.Huang Gan granules(HGGs)are commonly used to prevent...