EMODIN

作品数:113被引量:637H指数:15
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相关领域:医药卫生更多>>
相关作者:朱文元鲁严谭城张崇本顾军更多>>
相关机构:大连医科大学西南大学南方医科大学江苏省人民医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广西壮族自治区自然科学基金河南省自然科学基金更多>>
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Emodin promotes the recovery of rheumatoid arthritis by regulating the crosstalk between macrophage subsets and synovial fibroblast subsets被引量:1
《Animal Models and Experimental Medicine》2025年第1期44-56,共13页Lianying Cheng Xiaofeng Rong 
Background : To study the relationships among emodin, synovial fibroblasts (FLSs), and macrophages (STMs) to provide guidance for the use of emodin in rheumatoid arthritis (RA) treatment. Methods : RA clinical samples...
关键词:EMODIN fibroblast synoviocytes MACROPHAGES rheumatoid arthritis 
大黄素靶向ILK基因表达抑制高糖诱导的糖尿病肾病足细胞上皮间质转化
《中国老年学杂志》2024年第24期6103-6107,共5页张宁 崔萌 
目的 探讨大黄素(emodin)对高糖诱导的糖尿病肾病(DN)足细胞上皮间质转化(EMT)的影响及其对整合素连接激酶(ILK)基因表达的调控机制。方法 以高糖诱导足细胞构建DN足细胞损伤模型,细胞实验分为4组:对照(control)组,细胞培养基中添加5 mm...
关键词:大黄素(emodin) 糖尿病肾病(DN) 整合素连接激酶(ILK) 足细胞 上皮间质转化(EMT) 
Aloe emodin promotes mucosal healing by modifying the differentiation fate of enteroendocrine cells via regulating cellular free fatty acid sensitivity
《Acta Pharmaceutica Sinica B》2024年第9期3964-3982,共19页Weilian Bao Jiaren Lyu Guize Feng Linfeng Guo Dian Zhao Keyuan You Yang Liu Haidong Li Peng Du Daofeng Chen Xiaoyan Shen 
National Natural Science Foundation of China(Nos.82030113,82130108,and 82204717);China Postdoctoral Science Foundation(Nos.BX20220069 and 2021M700864).
The proper differentiation and reorganization of the intestinal epithelial cell population is critical to mucosal regeneration post injury.Label retaining cells(LRCs)expressing SRY-box transcription factor 9(SOX9)prom...
关键词:LRCS ISCS EECs IBD SOX9 Aloe emodin FFAR1 FOXO1 
Retraction: Emodin Inhibits Colon Cancer Cell Invasion and Migration by Suppressing Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Pathway
《Oncology Research》2024年第8期1375-1375,共1页Oncology Research Editorial Office 
Following the publication,concerns have been raised about a number of figures in this article.The transwell invasion assays shown in Fig.2A were strikingly similar to data appearing in different form in other articles...
关键词:INVASION Cancer COLON 
Unique Azolyl Acylhydrazonyl Hybridization of Aloe Emodins to Access Potential Antibacterial Agents
《Chinese Journal of Chemistry》2024年第15期1741-1758,共18页Yi-Xin Wang Zhao Deng Aisha Bibi Bo Fang Cheng-He Zhou 
supported by the National Natural Science Foundation of China(No.21971212);the Key Project of Innovation Research 2035 Pilot Plan of Southwest University(SWU-XDZD22007).
A type of unique azole-hybridized acylhydrazonyl aloe emodins(AAEs)were developed as new antibacterial agents for combating bacterial infections.Some target AAEs showed strong antibacterial activities,especially,tetra...
关键词:Aloe emodin Hydrazone HETEROCYCLE ANTIBACTERIAL Membrane damage 
Emodin suppresses alkali burn-induced corneal inflammation and neovascularization by the vascular endothelial growth factor receptor 2 signaling pathway
《Journal of Traditional Chinese Medicine》2024年第2期268-276,共9页ZHENG Xueying GUO Liang LAI Siyi LI Fengyue LIANG Mingli LIU Wanting MENG Chun LIU Guanghui 
Fujian Major Research Grants for Young and Middle-aged Health Professionals(No.2021ZQNZD012,Research and Development of Anti-Keratitis Protein Drug Sgp130);National Natural Science Foundation of China(No.81774369,Study on Mechanism of Yijing Decoction in Preventing Microvascular Damage of Early Diabetic Retinopathy based on MMPs/TIMPs)。
OBJECTIVE:To investigate the effects of emodin on alkali burn-induced corneal inflammation and neovascularization.METHODS:The ability of emodin to target vascular endothelial growth factor receptor 2(VEGFR2)was predic...
关键词:alkali burn EMODIN corneal inflammation corneal neovascularisation vascular endothelial growth factor receptor-2 signal transduction 
An efficient photocatalytic CO_(2) reduction system improved by emodin as a redox mediator
《Green Chemical Engineering》2023年第4期433-438,共6页Hua Gao Guoquan Liu Yong Zhu Zhibing Wen Xiao Liu Guan Wang Fei Li 
supported by the National Natural Science Foundation of China(22088102,21872016,and 22172018);the Fundamental Research Funds for the Central Universities of China(DUT20LAB307)
Solar-driven photoreduction of CO_(2)to value-added fuels such as CO,CH_(4),and CH_(3)OH is a promising approach for alleviating the greenhouse effect.Transition-metal-complex molecular catalysts exhibit high catalyti...
关键词:PHOTOCATALYSIS CO_(2)reduction Electron relay Organic dye 
Emodin Ameliorates High Glucose-Induced Podocyte Apoptosis via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway被引量:3
《Chinese Journal of Integrative Medicine》2023年第9期801-808,共8页LIU Hong CHEN Wei-dong HU Yang-lin YANG Wen-qiang HU Tao-tao WANG Huan-lan ZHANG Yan-min 
Supported by the Chinese Medicine Research Project of Hubei Provincial Health Commission(No.ZY2019Q024);Scientific Research Project of Wuhan Municipal Health Commission(No.WX20B11);Scientific Research Project of Wuhan Municipal Health Commission(No.WZ20C01)。
Objective To investigate the effect of emodin on high glucose(HG)-induced podocyte apoptosis and whether the potential anti-apoptotic mechanism of emodin is related to induction of adenosine-monophosphate-activated pr...
关键词:EMODIN diabetic nephropathy AUTOPHAGY podocyte apoptosis adenosine-monophosphate-activated protein kinase/mammalian target of rapamycin signaling pathways 
Dietary emodin alleviates lipopolysaccharide-induced intestinal mucosal barrier injury by regulating gut microbiota in piglets
《Animal Nutrition》2023年第3期152-162,共11页Wenjuan Xun Mengyao Ji Zhonghua Ma Tanjie Deng Wen Yang Guanyu Hou Liguang Shi Ting Cao 
supported by the Hainan Association’s Innovation Project for Science and Technology Young Talents(QCXM201907);the Scientific Research Foundation for Hainan University(KYQD(ZR)20037);the Innovative Research Projects for Graduate Students in Hainan Province(Qhys2021-163)。
This study was to determine the effects of dietary emodin(ED)on the intestinal mucosal barrier,nuclear factor kappa-B(NF-κB)pathways,and gut microbial flora in lipopolysaccharide(LPS)-induced piglets.Twenty-four wean...
关键词:EMODIN PIGLET Intestinal barrier function Nuclear factor kappa-B signalling Gut microbiota Short-chain fatty acid 
Advanced Oxidation Protein Products Regulate the Pharmacokinetics of Aloe-emodin,Emodin,Rhein,and Chrysophanol in Chronic Kidney Disease Rats
《Clinical Complementary Medicine and Pharmacology》2023年第3期8-18,共11页Tianrong Xun Xiaokang Wang Jingqian Zhao Zhufen Lin Haixing Feng Liqian Mo Xixiao Yang 
supported by Guangdong Science and Technology Program(No.2015B020211006);the Technology Project of Guangzhou City in China(No.201604020137);Shenzhen Foundation of Science and Technology(No.JCYJ20190814112205770);Research Foundation of Shenzhen Hospital of Southern Medical University(No.PY2021YM03);the Project of Traditional Chinese Medicine Bureau of Guangdong Province(No.20221273).
Background:As accelerators and products of the progression of chronic kidney disease(CKD),advanced oxidation protein products(AOPPs)affect the function of the liver.Huang Gan granules(HGGs)are commonly used to prevent...
关键词:Advanced oxidation protein products(AOPPs) Chronic kidney disease(CKD) Huang Gan granules(HGGs) ALOE-EMODIN EMODIN RHEIN CHRYSOPHANOL 
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