supported by National Key Research and Development Program (No. 2022YFC3502100, 2022YFC3502102-05);Joint Fund of Natural Fund of Shandong Province (No. ZR2021LZY036);Lunan Hope Pharmaceutical Co., Ltd. (No. 1520019013)。
Constipation is a common and prevalent digestive system disease in clinical practice, which seriously affects human physical and mental health. Currently, chemical drugs have good short-term therapeutic effects. Howev...
OBJECTIVE:To prepare aloe-emodin solid dispersion(AE-SD)and determine the metabolic process of AE and AE-SD in vivo.METHODS:AE-SD was prepared via solvent evaporation or solvent melting using PEG-6000 and PVP-K30 as c...
supported by Guangdong Science and Technology Program(No.2015B020211006);the Technology Project of Guangzhou City in China(No.201604020137);Shenzhen Foundation of Science and Technology(No.JCYJ20190814112205770);Research Foundation of Shenzhen Hospital of Southern Medical University(No.PY2021YM03);the Project of Traditional Chinese Medicine Bureau of Guangdong Province(No.20221273).
Background:As accelerators and products of the progression of chronic kidney disease(CKD),advanced oxidation protein products(AOPPs)affect the function of the liver.Huang Gan granules(HGGs)are commonly used to prevent...
Aloe vera plant is known worldwide for its medicinal properties and application in gel-based products such as shampoo,soap,and sunscreen.However,the demand for these gel-based products has led to a surplus production ...
the Major Program of the National Natural Science Foundation of China(81230081);the Translational Fund of the Sino-Russian Medical Research Center,Heilongjiang Academy of Medical Sciences(CR201814).
Hyperlipidemia(HPL)characterized by metabolic disorder of lipids and cholesterol is one of the important risk factors for cardiovascular diseases.Proprotein convertase subtilsin/kexin type 9(PCSK9)is a potent circulat...
Background:Anthraquinones are a possible treatment option for oncological patients due to their anti-cancer properties.Cancer patients often exhaust a plethora of resources that ultimately fail to provide fully curati...
supported by the National Key Technology R&D Program (2006BAI09B07-02)
This paper reports the extraction of aloe-emodin from aloe by microwave-assisted extraction. The effects of various factors, including the solvent, the ratio (mL/g) of the solvent to the sample, microwave irradiatio...
A high-performance liquid chromatography (HPLC) method has been developed for the first time to simultaneously quantify the four active ingredients, namely aloha, baicalein, aloe-emodin and wogonin, in Dangguilonghu...
the Ningbo Natural Science Foundation (No 2006A610047);the "151 Personal Training Project" of Zhejiang Province, China;the "Famous Professor Training Project" of Ningbo, China;the "Key Subjects Fund of Ningbo University (No XK0614052);the KC Wong Magna Fund at Ningbo Univer-sity.
Aim: The aim of this study was to investigate the effects of aloe-emodin, a natural compound from the root and rhizome of Rheum palmatum, on the growth of hu- man cervical cancer cells, HeLa. Methods: HeLa cells wer...
Supported by The Project of Heilongjiang Natural Science Foundation No. TD 2005-01;Department of Health, Heilongjiang Province No. 2006-391
AIM: To investigate the inhibitory effect and possible mechanism of action of schisandrin B in SC-B on gastric cancer cells in vitro.METHODS: SC-B consisted of schisandrin B, aloeemodin, and Astragalus polysaccharid...