云南高校图书馆联盟文献共享服务平台- CATECHOL-O-METHYLTRANSFERASE

CATECHOL-O-METHYLTRANSFERASE: 作品数：14被引量：24H指数：2; 导出分析报告; 相关作者：岳春林孙学川邓伟明张宗豪廖正宇更多>>; 相关机构：苏州大学解放军军事体育进修学院四川大学南昌大学附属口腔医院更多>>; 相关期刊：《Journal of Pharmaceutical Analysis》《Advances in Bioscience and Biotechnology》《Acta Biochimica et Biophysica Sinica》《心理科学》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划上海市自然科学基金国家教育部博士点基金更多>>

Interaction between catechol-O-methyltransferase Val/Met polymorphism and cognitive reserve for negative symptoms in schizophrenia: 《World Journal of Psychiatry》2024年第5期695-703,共9页Wen-Peng Hou Xiang-Qin Qin Wei-Wei Hou Yun-Yi Han Qi-Jing Bo Fang Dong Fu-Chun Zhou Xian-Bin Li Chuan-Yue Wang; Supported by the National Natural Science Foundation of China,No.81971250 and No.82171501;Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support,No.ZLRK202335;Early Psychosis Cohort Program of Beijing Anding Hospital,No.ADDL-03.; BACKGROUND Cognitive reserve(CR)and the catechol-O-methyltransferase(COMT)Val/Met polymorphism are reportedly linked to negative symptoms in schizophrenia.However,the regulatory effect of the COMT genotype on the rela...; 关键词：Catechol-O-methyltransferase Val/Met polymorphism Cognitive reserve Crystallized intelligence Negative symptoms SCHIZOPHRENIA

Analytical methodologies for sensing catechol-O-methyltransferase activity and their applications被引量：1: 《Journal of Pharmaceutical Analysis》2021年第1期15-27,共13页Fang-Yuan Wang Ping Wang Dong-Fang Zhao Frank J.Gonzalez Yu-Fan Fan Yang-Liu Xia Guang-Bo Ge Ling Yang; supported by the National Key Research and Development Program of China(2017YFC1700200,2017YFC1702000),the National Natural Science Foundation of China(81922070,81703604,81973286,81773687 and 81603187);Natural Science Foundation of Shanghai(18ZR1436500);Program of Shanghai Academic/Technology Research Leader(18XD1403600);Shuguang Program(18SG40)supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission;the project sponsored by the development fund for Shanghai talents(2019);the Key Science and Technology Program of Shenyang supported by Shenyang Science and Technology Bureau(17-230-9-05).; Mammalian catechol-O-methyltransferases(COMT)are an important class of conjugative enzymes,which play a key role in the metabolism and inactivation of catechol neurotransmitters,catechol estrogens and a wide range of ...; 关键词：Catechol-O-Methyltransferase(COMT) Enzymatic activity Probe substrate COMT inhibitor High-throughput screening

Excess Weight Loss after Bariatric Surgery: The Influence of Catechol-O-Methyltransferase (COMT) Polymorphism (Val108/158Met), Sociodemographic Variables and Physical Activity: 《Surgical Science》2020年第7期194-207,共14页Jessica Liebaert Harald Rudolf Bliem Christine Unterrainer Johann F. Kinzl; Background: In the treatment of morbid obesity bariatric surgery has become the method of choice. Dopamine is the primary modulator of the brain’s reward system and plays an essential role in the reg...; 关键词：COMT Polymorphism (Val108/158Met) Bariatric Surgery Excess Weight Loss (EWL) Physical Activity (PA)

Sevoflurane plays a reduced role in cognitive impairment compared with isoflurane: limited effect on fear memory retention被引量：9: 《Neural Regeneration Research》2020年第1期96-102,共7页Ying Du Xiang-Dan Gong Xin Fang Fang Xing Tian-Jiao Xia Xiao-Ping Gu; supported by the National Natural Science Foundation of China,No.81730033(to XPG),No.81701371(to TJX); Isoflurane and sevoflurane are both inhalation anesthetics,but in clinical application,sevoflurane has been considered to be less suitable for long-term anesthesia because of its catabolic compounds and potential neph...; 关键词：CATECHOL-O-METHYLTRANSFERASE cognitive impairment D1 dopamine receptors FEAR memory GLYCOGEN synthase kinase-3β ISOFLURANE NEUROTOXICOLOGY SEVOFLURANE

Spontaneous Regional Brain Activity in Healthy Individuals is Nonlinearly Modulated by the Interaction of ZNF804A rs1344706 and COMT rs4680 Polymorphisms: 《Neuroscience Bulletin》2019年第4期735-742,共8页Lingling Cui Fei Wang Miao Chang Zhiyang Yin Guoguang Fan Yanzhuo Song Yange Wei Yixiao Xu Yifan Zhang Yanqing Tang Xiaohong Gong Ke Xu; supported by the National Basic Research Development Program of China (2016YFC0906400, 2016YFC1306900 and 2016YFC0904300);the National Natural Science Foundation of China (81571311 and 81571331);the National Science Fund for Distinguished Young Scholars of China (81725005);the National High Tech Development Project (863 Project) of China (2015AA020513);the Science and Technology Project of Liaoning Province, China (2015225018);the Educational Foundation (Pandeng Scholarship) of Liaoning Province, China;the support of Department of Radiology and Psychiatry, First Affiliated Hospital of China Medical University; ZNF804A rs1344706 has been identified as one of the risk genes for schizophrenia.However,the neural mechanisms underlying this association are unknown.Given that ZNF804A upregulates the expression of COMT,we hypothesi...; 关键词：Zinc FINGER protein 804A CATECHOL-O-METHYLTRANSFERASE AMPLITUDES of LOW-FREQUENCY fluctuations fMRI

Overexpression of catechol-O-methyltransferase occurs early in the progression of pancreatic cancer: 《Journal of Pancreatology》2018年第1期39-44,共6页Hongmei Dai Xianze Wang Xiafei Hong Huanwen Wu Wenyu Di Wenze Wang Peiran Xu Congwei Jia Jing Wang Hao Chen Jialin Jiang Rui Jiang Wenming Wu Yupei Zhao; the National Natural Science Foundation of China(NSFC)(81272768);National Natural Science Foundation of China(NSFC)(81573009); Aims:Catechol-O-methyltransferase(COMT)plays a role in many kinds of cancer,and its high expression in pancreatic cancer has been found to be related to better prognosis.However,the expression and biological significa...; 关键词：CATECHOL-O-METHYLTRANSFERASE Pancreatic cancer Pancreatic intraepithelial neoplasia

Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots （Danshen）被引量：8: 《Acta Pharmacologica Sinica》2015年第5期627-643,共17页Dan-dan TIAN Wei-wei JIA Xin-wei LIU Dan-dan WANG Jun-hua LIU Jia-jia DONG Li LI Fei-fei DU Fang XU Feng-qing WANG Yan SUN Yu-xing HUANG Mei-juan LI Li-hong HU Yan ZHU Xiu-mei GAO Chuan LI Jun-ling YANG; Aim： Tanshinol is an important catechol in the antianginal herb Salvia miltiorrhiza roots （Danshen）. This study aimed to characterize tanshinol methylation. Methods： Metabolites of tanshinol were analyzed by liqui...; 关键词：tanshinol METHYLATION CATECHOL-O-METHYLTRANSFERASE herb-drug interaction Salvia miltiorrhiza roots DANSHEN

DNA methylation in schizophrenia: progress and challenges被引量：2: 《Science Bulletin》2015年第2期149-155,I0001,共8页宗小芬胡茂林李宗昌曹红宝陈晓岗唐劲松; supported by the National Natural Science Foundation of China(81271484 and 81471361 toX.C,30900486 and 81371480 to J.T);the National Key Basic Research and Development Program(2012CB517904 to X.C); Schizophrenia is a heterogeneous psychiatric disorder broadly accepted being caused by genetic and environmental factors. Although conventional genetic studies have identified some candidate genes for schizophrenia, l...; 关键词：SCHIZOPHRENIA EPIGENETICS DNA methylation REELIN CATECHOL-O-METHYLTRANSFERASE

HPLC法同时测定大鼠肝微粒中原儿茶酸和香草酸的含量: 《西南国防医药》2014年第6期589-591,共3页代晶石明芯王佳慧; 四川省教育厅理科重点项目(12ZA026); 目的：建立测定大鼠离体肝微粒中儿茶酚氧甲基转移酶（ COMT）底物（原儿茶酸）和代谢产物（香草酸）含量的HPLC法。方法离体肝微粒体样品经酸化后，乙酸乙酯提取。以绿原酸作为内标，色谱柱为 Welchrom C18，流动相为甲醇：0.1％磷酸...; 关键词：高效液相色谱法儿茶酚氧甲基转移酶原儿茶酸香草酸肝微粒体 catechol-O-methyltransferase(COMT)

Histone acetyltransferase p300 promotes MKLl-mediated transactivation of catechol-O-methyltransferase gene被引量：1: 《Acta Biochimica et Biophysica Sinica》2013年第12期1002-1010,共9页Zhipeng Liu Xuegang Luo Lei Liu Wenwen Zhao Shu Guo Yu Guo Nan Wang Hongpeng He XinghuaLiao Wenjian Ma Hao Zhou Tongcun Zhang; This work was supported by grants from the National Program on Key Basic Research Project （973 Program）（No. 2009CB825504）, the National Natural Science Foundation of China （No. 31000343, No. 31300642, No. 31071126）, the Research Fund for the Doctoral Program of Higher Education of China （No. 20111208110001）, the Tianjin Research Program of Application Foundation and Advanced Technology （No. I1CYBJC26200）, and the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China （No. IRY1166）.; Previous studies have revealed that histone acetyltransferase p300 is recruited to the promoters of certain cardiac and smooth muscle specific genes to enhance the transactivation activity of myocardin, which is a mas...; 关键词：cell metabolism COMT MKL1 P300 transcriptional regulation

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