supported by the National Natural Science Foundation of China(grant nos.21977063,92053110,and 22177061);the National Key Research and Development Program of China(grant no.2018YFA0902000);the China Postdoctoral Science Foundation(grant no.2020M680090);the Qilu Youth Scholar Program of Shandong University,the Central Government Guide Local Science and Technology Development Funds(grant no.YDZX20203700002579);the Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences(grant no.2021-RC350-002);the CAMS Innovation Fund for Medical Sciences(CIFMS)(grant no.2021-1-I2M-026).
Lipoteichoic acids(LTAs)are macroamphiphiles composed of alditol,lipid,phosphate,and carbohydrate units.Due to their inherent complexity,it is a severe challenge to access LTAs with structural integrity from natural s...
Project supported by the National Natural Science Foundation of China (No. 20172049).
Convenient procedure for coupling of 1,2,3,5-tetra-O-acetyl-β-D-ribofuranose and 4-nitroimidazole was provided to obtain β-anomer as major product. A novel category of nucleoside analogues with an imidazole base moi...
Acetyl bromide cleaved 2,3,4-tri-O-benzyl-l,6-anhydro-B-D-glucopyranose (la) or 2,3,4-tri-O-benzyl-1,6-anhydro-B-Z)-galactopyranose (1a') to give the corresponding a-D-pyranosyl bromides (2). Reaction of 2 with ROH/di...
Heterocyclic ketene aminals 1 or 2 reacted with 2.3. 4. 6-tetra-O-acetyl-α-D-glucopyranosyl bromide using mercuric cyanide-calcium hydride or mercuric cyanide-molecular sieve 4A as catalyst to give the O-glycosidated...
A series of compounds had been synthesised from 1.6-anhydro-2,4-di-O-benzyl-β-D-glucopyranose with good yields.The The effects of C-3 protecting groups on ring-opening reaction and the glycosidation of α-D-glucopyra...