ABERRATIONS

作品数:119被引量:315H指数:9
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Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein被引量:1
《World Journal of Gastroenterology》2016年第48期10680-10686,共7页Francois Ghiringhelli Corentin Richard Sandy Chevrier Frédérique Végran Romain Boidot 
Precision medicine is defined by the administration of drugs based on the tumor's particular genetic characteristics. It is developing quickly in the field of cancer therapy. For example, KRAS, NRAS and BRAF genetic t...
关键词:COLORECTAL cancer EXOME analysis Genetic ABERRATIONS HOMOLOGOUS REPAIR deficiency Precision medicine 
HER2 aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologists被引量:5
《World Journal of Gastroenterology》2016年第35期7926-7937,共12页Nicola Fusco Silvano Bosari 
Management of cancers of the digestive system has progressed rapidly into the molecular era. Despite the significant recent achievements in the diagnosis and treatment of these patients, the number of deaths for these...
关键词:HER2 Digestive system Gastrointestinal tract Gastric cancer Colon cancer Esophageal cancer Gastroesophageal junction cancer Biliary tract cancer Gallbladder cancer Liver cancer Pancreas cancer 
MicroRNA aberrations:An emerging field for gallbladdercancer management被引量:16
《World Journal of Gastroenterology》2016年第5期1787-1799,共13页Vishal Chandra Jong Joo Kim Balraj Mittal Rajani Rai 
Gallbladder cancer(GBC) is infrequent but most lethal biliary tract malignancy characterized by an advanced stage diagnosis and poor survival rates attributed to absence of specific symptoms and effective treatment op...
关键词:GALLBLADDER cancer MICRORNA ABERRATIONS Tumor SUPPRESSOR gene ONCOGENE BIOMARKER Therapy 
Managing injuries of hepatic duct confluence variants after major hepatobiliary surgery:An algorithmic approach被引量:4
《World Journal of Gastroenterology》2008年第19期3049-3053,共5页Georgios Fragulidis Athanasios Marinis Andreas Polydorou Christos Konstantinidis Georgios Anastasopoulos John Contis Dionysios Voros Vassilios Smyrniotis 
AIM:To investigate injuries of anatomy variants of hepatic duct confluence during hepatobiliary surgery and their impact on morbidity and mortality of these procedures. An algorithmic approach for the management of th...
关键词:Biliary aberrations Bile duct injury Postope-rative bile leakage Hepatic duct confluence HEPATECTOMY 
Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families:Implications for genetic testing被引量:9
《World Journal of Gastroenterology》2007年第19期2727-2732,共6页Janos Papp Marietta E Kovacs Edith Olah 
Supported by the Hungarian Research Grants OTKA T-046570, NKFPI-00024/2005 and ETT 397/2006
AIM: To analyze the prevalence of germline MLH1 and MSH2 gene mutations and evaluate the clinical characteristics of Hungarian hereditary non-polyposis colorectal cancer (HNPCC) families. METHODS: Thirty-six kindreds ...
关键词:Germline mutation Hereditary non-polyposis colorectal cancer MLH1 MSH2 REARRANGEMENT 
Complete or partial trisomy 3 in gastro-intestinal MALT lymphomas co-occurs with aberrations at 18q21 and correlates with advanced disease stage:A study on 25 cases被引量:2
《World Journal of Gastroenterology》2005年第46期7384-7385,共2页Jens Krugmann Alexandar Tzankov Stephan Dirnhofer Falko Fend Dominik Wolf Reiner Siebert Pensiri Probst Martin Erdel 
Taji et al . have reported in their study on 13 patients with gastric mucosa-associated lymphoid tissue (MALT) lymphomas an aggressive tumor course in trisomy 3 positive cases. The authors analyzed only stage I pat...
关键词:MALT lymphoma Trisomy 3 Trisomy 18 
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