MULTIVALENCY

作品数：6被引量：12H指数：2
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Long way up:rethink diseases in light of phase separation and phase transition被引量：1
《Protein & Cell》2024年第7期475-492,共18页Mingrui Ding Weifan Xu Gaofeng Pei Pilong Li 
National Key Research and Development Program of China(2019YFA0508403 to P.L.);National Natural Science Foundation of China(32330024 to P.L.,32100547 to M.R.,and 32100990 to W.F.).
Biomolecular condensation, driven by multivalency, serves as a fundamental mechanism within cells, facilitating the formation of distinct compartments, including membraneless organelles that play essential roles in va...
关键词：MULTIVALENCY COMPARTMENTS aberant phase separation THERAPEUTICS gain or loss of phase separation DISEASES 
Rational multivalency construction enables bactericidal effect amplification and dynamic biomaterial design被引量：1
《The Innovation》2023年第5期59-68,共10页Xu Chen Xinrui Li Wenbo He Miao Wang Ang Gao Liping Tong Shun Guo Huaiyu Wang Guoqing Pan 
We acknowledge the National Natural Science Foundation of China(32222041,21875092 and 82272157);National Natural Science Foundation of Jiangsu Province(BK20220059);National Key Research and Development Program of China(2019YFA0112000);Innovation and Entrepreneurship Program of Jiangsu Province,and the“Jiangsu Specially-Appointed Professor”Program.
The multivalency of bioligands in living systems brings inspiration for not only the discovery of biological mechanisms but also the design of extracellular matrix(ECM)-mimicking biomaterials.However,designing control...
关键词：HEALING enable DYNAMIC 
Rim-differentiation vs. mixture of constitutional isomers: A binding study between pillar[5]arene-based glycoclusters and lectins from pathogenic bacteria
《Chinese Chemical Letters》2023年第2期214-218,共5页Zhiping Liu Fanny Demontrond Anne Imberty Andrew C.-H.Sue Sébastien Vidal Hongxia Zhao 
Financial supports from the National Natural Science Foundation of China (No. 21801184);the Tianjin Municipal Applied Basic and Key Research Scheme of China (No. 18JCQNJC06400);Xiamen University, Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study (No. SN-ZJU-SIAS-006);Université de Lyon, the French Agence Nationale de la Recherche (Dyna Sweet, ANR-08-BLAN-0305);Glyco@Alps (ANR-15-IDEX-02);Labex Arcane/CBH-EUR-GS (ANR-17-EURE-0003) are gratefully acknowledged。
Macrocycle-based glycoclusters, on account of their promising anti-adhesive properties against bacteria,are potential therapeutic alternatives to classic antibiotics through the much less explored anti-adhesive strate...
关键词：Glycocluster LECTIN Pillararene MULTIVALENCY Constitutional purity 
Macroscopic Supramolecular Assembly and Its Applications被引量：7
《Chinese Journal of Polymer Science》2018年第3期306-321,共16页Meng-Jiao Cheng Qian Zhang Feng Shi 
Macroscopic supramolecular assembly(MSA)has been a recent progress in supramolecular chemistry.MSA mainly focuses on studies of the building blocks with a size beyond ten micrometers and the non-covalent interactions ...
关键词：Macroscopic supramolecular assembly MULTIVALENCY Supramolecular materials 3D ordered structures Precise assembly 
Semiotics Turning Cross-Cultural被引量：3
《Language and Semiotic Studies》2015年第3期1-12,共12页Semiotics Turning Cross-Cultural 
Semiotics,mostly as a theory of meaning,has a long history both in China and in the West.Although there had been little interaction between these two independent traditions before the 20th century,we can fi nd some in...
关键词：SEMIOTICS cross-cultural studies ontological realism Peircean trichotomy Chinese scripts vehicular diversity and multivalency cognitive theory of metaphor 
Synthesis and Enhanced Guest-Binding Affinities of Dendrimer-Based Cyclophane Tetramer and Octamer
《Advances in Chemical Engineering and Science》2013年第3期33-37,共5页Osamu Hayashida Tomomi Nakashima Yu Kaku 
Dendritic cyclophane tetramer and octamer were prepared by aminolysis of succinimidyl ester derivative of tetraaza [6.1.6.1] paracyclophane with the corresponding poly(amidoamine) dendrimers as a scaffold, followed by...
关键词：CYCLOPHANE OLIGOMER HOST-GUEST Chemistry MULTIVALENCY Effect 
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