OPHIOPOGONIN

作品数：5被引量：34H指数：3
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相关领域：医药卫生更多>>
相关作者：巩克民张鹏威赵怀清王宇光高月更多>>
相关机构：盐城卫生职业技术学院沈阳药科大学海南医学院江苏省中医院更多>>
相关期刊：《Plant Diseases and Pests》《Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《分析仪器》更多>>
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Antitumor Effect and Molecular Mechanism of Ophiopogonin B
《Plant Diseases and Pests》2023年第3期27-29,36,共4页Jingchao WANG Mingxinzhi WANG Hai CHEN Quan QUAN Xichun HUANG Chenghao JIN 
Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16);Innovation and Entrepreneurship Training Program for College Students in Heilongjiang Province(202210223048).
Ophiopogonin B is a kind of saponin active substance extracted and purified from Ophiopogon japonicus,and plays an antitumor role by inhibiting cancer cell adhesion,invasion and proliferation,and inducing tumor cell a...
关键词：Ophiopogonin B ANTITUMOR Cell proliferation APOPTOSIS 
Author Correction:Ophiopogonin D maintains Ca^(2+)homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stress被引量：1
《Acta Pharmacologica Sinica》2020年第12期1622-1622,共1页Wen-ting You Tao Zhou Zeng-chun Ma Qian-de Liang Cheng-rong Xiao Xiang-lin Tang Hong-ling Tan Bo-li Zhang Yu-guang Wang Yue Gao 
The authors realized that the representative images of DMSO group in Fig.7a were found to be misplaced due to the mishandling in the paper preparation.All the authors agree on the correction of our negligence and the ...
关键词：CORRECTION MAINTAIN CONCLUSION 
Ophiopogonin D maintains Ca2＋ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/ EETs and suppressing ER stress被引量：21
《Acta Pharmacologica Sinica》2016年第3期368-381,共14页Wen-ting YOU Tao ZHOU Zeng-chun MA Qian-de LIANG Cheng-rong XIAO Xiang-lin TANG Hong-ling TAN Bo-li ZHANG Yu-guang WANG Yue GAO 
Aim： CYP2J3 in myocardium metabolizes arachidonic acid to 4 regioisomeric epoxyeicosatrienoic acids （EETs）, which have diverse biological activities in rat heart. In this study we examined whether CYP2J3 was involv...
关键词：ophiopogonin D CARDIOMYOCYTES angiotensin II CYP2J3 epoxyeicosatrienoic acid ER stress Ca2＋ homeostasis BAPTA 
Ophiopogonin D inhibits cell proliferation,causes cell cycle arrest at G_2/M,and induces apoptosis in human breast carcinoma MCF-7 cells被引量：9
《Journal of Integrative Medicine》2016年第1期51-59,共9页Qing-qing Zang Lu Zhang Ning Gao Cheng Huang 
Financial assistance was provided by grants from the National Natural Science Foundation of China(No.81173141)
OBJECTIVE： To investigate the effects of ophiopogonin D on human breast cancer MCF-7 cells METHODS： Cell viability was assessed by 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide and colony formation ...
关键词：ophiopogonin D G2/M arrest APOPTOSIS cyclin B1 CASPASES breast neoplasms antineoplasticagents  phytogenic in vitro 
RP-HPLC法测定麦冬中麦冬皂苷D’的含量被引量：5
《分析仪器》2014年第2期73-76,共4页巩克民 赵怀清 张鹏威 
海南省重点科技计划项目(ZDXM20120095);浙江省公益技术研究社会发展项目(2012C23082);海南医学院科研培育基金(HY2010-011)
目的：建立RP-HPLC 法测定麦冬中麦冬皂苷D’的含量，方法：采用DiamonsilTM C18色谱柱（200 mm ×4.6 mm ，5μm），柱温为33℃，流动相为水-乙腈（体积比52∶48），流速0.80 mL·min^-1，检测波长208nm ．结果：麦冬皂苷D’的质量浓度...
关键词：反相高效液相色谱法 麦冬 麦冬皂苷D’ 含量测定 OPHIOPOGONIN D’ 
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