SEROCONVERSION

作品数:35被引量:227H指数:9
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相关领域:医药卫生更多>>
相关作者:熊永红孔香兰杨德云更多>>
相关机构:新疆医科大学第五附属医院更多>>
相关期刊:《Cellular & Molecular Immunology》《Science China(Life Sciences)》《World Journal of Gastroenterology》《Journal of Health Science》更多>>
相关基金:国家自然科学基金广东省自然科学基金国家重点基础研究发展计划国家教育部博士点基金更多>>
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Hepatitis B core-related antigen:Are we near a treatment endpoint?
《World Journal of Gastroenterology》2022年第27期3532-3534,共3页Tarana Gupta 
Different serological and virological markers in chronic hepatitis B patients guide staging of viral infection,and initiation and response to therapy.Due to the persistence of intrahepatic covalently closed circular D...
关键词:Hepatitis B core-related antigen Chronic hepatitis B Covalently closed circular DNA Hepatitis B e antigen seroconversion Hepatitis B virus DNA Pregenomic RNA 
Serum hepatitis B core-related antigen as a surrogate marker of hepatitis B e antigen seroconversion in chronic hepatitis B被引量:5
《World Journal of Gastroenterology》2021年第40期6927-6938,共12页Xiu-Mei Chi Xiao-Mei Wang Zhong-Feng Wang Rui-Hong Wu Xiu-Zhu Gao Hong-Qin Xu Yan-Hua Ding Jun-Qi Niu 
by National Science and Technology Major Project,No.2017ZX10302201,No.2017ZX09304004 and No.2014ZX10002002;National Program on Key Basic Research Project(973 Program),No.2015CB554304.
BACKGROUND Quantitative hepatitis B core-related antigen(qHBcrAg)has a better correlation with intrahepatic hepatitis B virus(HBV)covalently closed circular DNA(cccDNA)than HBV DNA or hepatitis B e antigen(HBeAg),but ...
关键词:Hepatitis B virus Hepatitis B core antigen Hepatitis B virus DNA Detection Liver biopsy Pregenomic RNA Quantitative hepatitis B core-related antigen Receiver operating characteristic SEROCONVERSION Correlation 
Efficacy of a Chinese herbal formula on hepatitis B e antigenpositive chronic hepatitis B patients被引量:9
《World Journal of Gastroenterology》2020年第30期4501-4522,共22页Yu-Feng Xing Chun-Shan Wei Tian-Ran Zhou Dan-Ping Huang Wei-Chao Zhong Bin Chen Hua Jin Xiao-Yu Hu Zhi-Yun Yang Qing He Kai-Ping Jiang Jun-Min Jiang Zhen-Bin Hu Xin Deng Fan Yang Feng-Yi Li Gang Zhao Li-Chun Wang Yu-Qiang Mi Zuo-Jiong Gong Peng Guo Jian-Hua Wu Wei-Qun Shi Hong-Zhi Yang Da-Qiao Zhou Guang-Dong Tong 
Supported by the National Natural Science Foundation of China,No.81174263;National Science and Technology Major Project during the 12th Five-year Plan Period,No.2012ZX1005006;Sanming Project of Medicine in Shenzhen,Guangdong Province,China,No.SZSM201612074;and Science and Technology Planning Project of Guangdong Province,China,No.2017A020213016.
BACKGROUND No guideline recommends antiviral therapy for hepatitis B e antigen(HBeAg)-positive chronic hepatitis B patients with persistently normal alanine aminotransferase levels and a high hepatitis B virus(HBV)DNA...
关键词:Chronic hepatitis B Chinese Herbal Formula treatment Hepatitis B e antigen clearance Hepatitis B e antigen seroconversion Hepatitis B virus DNA reduction Clinical trial 
Serum hepatitis B virus RNA is a predictor of HBeAg seroconversion and virological response with entecavir treatment in chronic hepatitis B patients被引量:22
《World Journal of Gastroenterology》2019年第6期719-728,共10页Hao Luo Xia-Xia Zhang Li-Hua Cao Ning Tan Qian Kang Hong-Li Xi Min Yu Xiao-Yuan Xu 
the 13th Five-Year Plan,No.2018ZX09206005-002
BACKGROUND Characteristics of alterations of serum hepatitis B virus(HBV) RNA in different chronic hepatitis B(CHB) patients still cannot be fully explained. Whether HBV RNA can predict HBeAg seroconversion is still c...
关键词:Chronic HEPATITIS B HEPATITIS B virus RNA Virological response HBeAg SEROCONVERSION ENTECAVIR 
Clinical features of HBs Ag seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study被引量:4
《World Journal of Gastroenterology》2016年第44期9836-9843,共8页Young Min Park Seong Gyu Lee 
AIM To investigate the characteristic features of hepatitis B surface antigen(HBs Ag) seroclearance among Korean hepatitis B virus(HBV) carriers.METHODS Carriers with HBs Ag seroclearance were selected by analyzing lo...
关键词:Hepatocellular carcinoma HEPATITIS B virus HEPATITIS B Surface ANTIGEN HBS AG SEROCONVERSION HEPATITIS B e ANTIGEN HBE AG Liver cirrhosis 
Models for predicting hepatitis B e antigen seroconversion in response to interferon-α in chronic hepatitis B patients被引量:14
《World Journal of Gastroenterology》2015年第18期5668-5676,共9页Chang-Tai Wang Ya-Fei Zhang Bing-Hu Sun Yu Dai Hui-Lan Zhu Yuan-Hong Xu Meng-Ji Lu Dong-Liang Yang Xu Li Zhen-Hua Zhang 
Supported by Specialized Research Fund for the Doctoral Program of Higher Education of China,No.20093420120005;National Science Foundation of China,No.30771907
AIM:To develop models to predict hepatitis B e antigen(HBe Ag)seroconversion in response to interferon(IFN)-αtreatment in chronic hepatitis B patients.METHODS:We enrolled 147 treatment-nave HBe Agpositive chronic h...
关键词:CHRONIC HEPATITIS B INTERFERON HEPATITIS B e ANTIGEN Treatment Model 
Chronic hepatitis B in children with or without malignancies:A 13-year follow-up
《World Journal of Gastroenterology》2015年第7期2073-2079,共7页Merve Usta Nafiye Urganci Zeynep Yildiz Yildlrmak Sema Dogan Vural 
AIM:To evaluate the outcome of chronic hepatitis B(CHB)in children with or without malignancies.METHODS:Twenty four children(15 boys and 9 girls)with malignancies,followed up by the pediatric gastroenterology outpatie...
关键词:Chronic hepatitis B Children Pediatric malignancies SEROCONVERSION Course of the disease 
Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion被引量:4
《World Journal of Gastroenterology》2015年第2期541-548,共8页Nozomi Kamijo Akihiro Matsumoto Takeji Umemura Soichiro Shibata Yuki Ichikawa Takefumi Kimura Michiharu Komatsu Eiji Tanaka 
Supported by Research grant from the Ministry of Health,Labor,and Welfare of Japan
AIM: To investigate the role of pre-core and basal core promoter(BCP) mutations before and after hepatitis Be antigen(HBe Ag) seroconversion.METHODS: The proportion of pre-core(G1896A) and basal core promoter(A1762T a...
关键词:SEROCONVERSION HEPATITIS B core-related ANTIGEN Pr 
Hepatitis B surface antigen seroconversion after HBV reactivation in non-Hodgkin's lymphoma被引量:4
《World Journal of Gastroenterology》2014年第17期5165-5170,共6页Wei-Ping Liu Wen Zheng Yu-Qin Song Ling-Yan Ping Gui-Qiang Wang Jun Zhu 
Supported by National Natural Science Foundation of China,Grant No.81241073;Peking University Cancer Hospital Foundation for Scientific Research,Grant No.2013-Autonomous-9
Reactivation of hepatitis B virus(HBV)can occur in lymphoma patients infected with HBV when they receive chemotherapy or immunotherapy.Prophylactic administration of lamivudine(LAM)reduces the morbidity and mortality ...
关键词:Hepatitis B surface antigen  Seroconversion  Non-Hodgkin’ s lymphoma  Rituximab  Entecavir 
Durability of viral response after off-treatment in HBeAg positive chronic hepatitis B被引量:7
《World Journal of Gastroenterology》2012年第43期6277-6283,共7页Myeong Jun Song Do Seon Song Hee Yeon Kim Sun Hong Yoo Si Hyun Bae Jong Young Choi Seung Kew Yoon Yong-Han Paik June Sung Lee Hyun Woong Lee Hyung Joon Kim 
AIM:To evaluate the durability in hepatitis B e antigen (HBeAg) positive chronic hepatitis B patients who discontinued antiviral treatment. METHODS:A total of 48 HBeAg positive chronic hepatitis B patients who were ad...
关键词:DURABILITY SEROCONVERSION Chronic hepatitis B Hepatitis B e antigen positive RECURRENCE CONSOLIDATION 
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