ANALOGUES

作品数：349被引量：462H指数：9
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相关机构：北京大学沈阳药科大学北京医科大学辽宁大学更多>>
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Applying palaeoecological analogues to contemporary challenges:community-level effects of canopy gaps caused by systematic decline of a prevalent tree species
《Journal of Forestry Research》2025年第1期293-310,共18页Julia Webb Anne E.Goodenough 
Temperate woodland vegetation is initially determined by spatiotemporal and historical factors,mediated by complex biotic interactions.However,catastrophic events such as disease outbreaks(e.g.,sweet chestnut blight,a...
关键词：Canopy opening Community composition Palaeoecological analogue Disturbance Cascade effects 
Design and photophysical characterization of quasi-intrinsic fluorescent probes utilized in DNA sequencing
《Chinese Physics B》2025年第2期241-248,共8页Yaning Zhang Yongkang Lyu Zhizheng Cao Xiaolin Chen Qingtian Meng Changzhe Zhang 
Project supported by the National Natural Science Foundation of China(Grant Nos.11804195,11847224,11674198,and 12274265);the Natural Science Foundation of Shandong Province,China(Grant Nos.ZR2018BA034 and ZR2022MA006)。
To understand the gene-based biological processes in-depth,the single-molecule real-time sequencing has drawn increasing attention with promoted by the Human Genome Project.Herein,a set of newly designed canonical flu...
关键词：DNA sequencing base analogues fluorescent probe 
Malate initiates a proton-sensing pathway essential for pH regulation of inflammation
《Signal Transduction and Targeted Therapy》2025年第1期446-470,共25页Yu-jia-nan Chen Rong-chen Shi Yuan-cai Xiang Li Fan Hong Tang Gang He Mei Zhou Xin-zhe Feng Jin-dong Tan Pan Huang Xiao Ye Kun Zhao Wen-yu Fu Liu-li Li Xu-ting Bian Huan Chen Feng Wang Teng Wang Chen-ke Zhang Bing-hua Zhou Wan Chen Tao-tao Liang Jing-tong Lv Xia Kang You-xing Shi Ellen Kim Yin-hua Qin Aubryanna Hettinghouse Kai-di Wang Xiang-li Zhao Ming-yu Yang Yu-zhen Tang Hai-long Piao Lin Guo Chuan-ju Liu Hong-ming Miao Kang-lai Tang 
supported by grants from the National Natural Science Foundation of China 82130071,82072516(Kanglai Tang);Sports Injury Repair and Reconstruction Research Innovative Team 41CZDH,Personalized Training Program of Leading Talent Training Object 414ZB2(Kanglai Tang);National Key R&D Program of China 2021YFC2401300(Lin Guo);National Natural Science Foundation of China 82173134(Hongming Miao);The Funding of Jinfeng Laboratory and Chongqing Outstanding Youth Fund CSTB2022NSCQ-JQX0010(Hongming Miao);NIH research grants R01AR062207,R01AR061484,R01AR076900,R01NS103931(Chuanju Liu);NIH research grants 1S10OD010582-01A1(Beatrix Ueberheide).
Metabolites can double as a signaling modality that initiates physiological adaptations.Metabolism,a chemical language encoding biological information,has been recognized as a powerful principle directing inflammatory...
关键词：interaction restrained ANALOGUES 
Pictet-spengler/transamination cascade reaction of indoles for modular synthesis of marinoquinoline analogues
《Green Synthesis and Catalysis》2024年第4期310-314,共5页Jinjin Chen Pingyu Jiang Xinping Liu Huawen Huang Guojiang Mao Guo-Jun Deng 
Support by the National Natural Science Foundation of China(Nos.22271244 and 22071211);the Hunan Provincial Natural Science Foundation of China(Nos.2023JJ40561 and 2022JJ40359);the Hunan Provincial Health Commission Foundation(B202313020111);Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(No.2022C02)is gratefully acknowledged.
The Pictet-Spengler/transamination cascade reaction enables modular synthesis of marinoquinoline analoguesthrough three-component indole ring-expansion/cyclization in the manner of novel N1–C2 cleavage of indoles.Thi...
关键词：Pictet-spengler reaction Indole ring-expansion N1-C2 cleavage INDOLE Marinoquinoline analogues 
Targeting STAT3 signaling pathway by curcumin and its analogues for breast cancer:A narrative review
《Animal Models and Experimental Medicine》2024年第6期853-867,共15页Maryam Golmohammadi Mohammad Yassin Zamanian Ahmed Muzahem Al-Ani Thaer L.Jabbar Ali Kamil Kareem Zeinab Hashem Aghaei Hossein Tahernia Ahmed Hjazi Saad Abdul-ridh Jissir Elham Hakimizadeh 
Background:Breast cancer(BC)continues to be a significant global health issue,with a rising number of cases requiring ongoing research and innovation in treatment strategies.Curcumin(CUR),a natural compound derived fr...
关键词：apoptosis cell proliferation CURCUMIN curcumin analogues STAT3 
Cashiers and bisphenols:Occupational exposure and health implications in south China
《Emerging Contaminants》2024年第4期68-74,共7页Zhenni Zhu Yanan Pan Xiang Chen Xin Wei Xiaoyue Zhou Zixiong Tang Renli Yin Xiaoyang Jiao Adela Jing Li 
Funds for Youth Cultivation(4200/221321)at South China Agricultural University,the National Natural Science Foundation of China(42207490,42277427,22206053);the Guangdong Province Natural Science Foundation(2021A1515110852 and 2021B1212040008);the Start-up Funds for Talent Recruitment(4200/221068)all provided support for this work.
Bisphenols are ubiquitous chemicals used in various industries,raising concerns due to their potential to disrupt endocrine systems,particularly among occupational populations.This study concurrently assessed bispheno...
关键词：BPA BPA analogues Cashiers Urine Risk assessment 
Effect of Fluorine Atoms and Piperazine Rings on Biotoxicity of Norfloxacin Analogues:Combined Experimental and Theoretical Study
《Environment & Health》2024年第12期886-901,共16页Chuanxi Yang Xiaoning Wang Xinyan Zhao Yongkun Wu Jingyan Lin Yuhan Zhao Yiyong Xu Kaipeng Sun Chao Zhang Ziheng Wan Weihua Zhao Yihua Xiao Haofen Sun Dong Chen Wenping Dong Tieyu Wang Weiliang Wang 
To clarify the effect of the fluorine atom and piperazine ring on norfloxacin(NOR),NOR degradation products(NOR-DPs,P1−P8)were generated via UV combined with hydrogen peroxide(UV/H2O2)technology.NOR degradation did no...
关键词：NORFLOXACIN biotoxicity inhibition effect molecular docking structure−activity relationship 
Crystalline Boron-Centered Analogues of Müller's Hydrocarbon
《Chinese Journal of Chemistry》2024年第20期2507-2513,共7页Guo Pan Qidi Bao Xiaona Liu Yuqi Jiang Ren Zhou Tianze Xu Qianli Li Yuanting Su 
support from the National Natural Science Foundation of China(22371197 and 22001184);Natural Science Foundation of Jiangsu Province(BK20200849).
Müller's hydrocarbon is a well-known open-shell singlet diradicaloid,yet its structural determination and redox property remain elusive due to its extremely high reactivity.Herein,we report the successful synthesis a...
关键词：Diradicaloids Muller's hydrocarbon Boron Open-shell singlets X-ray diffraction 
Enhanced Research Needed on the Structural Analogues of Chlorinated Paraffins as Emerging Contaminants of Concern
《Environment & Health》2024年第10期681-683,共3页Weifang Chen Dazhou Ren Qian Liu Qunfang Zhou Jiyan Liu Guibin Jiang 
supported by the China Postdoctoral Science Foundation under Grant Number 2023M733678;the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0750100);the National Natural Science Foundation of China(No.22193051).
INTRODUCTION Structural analogues of chlorinated paraffins(CPs)are compounds that contain the chlorinated n-alkanes skeleton of CPs and other functional groups.Recently,some structural analogues of CPs at high levels ...
关键词：ANALOGUES chlorinated ALKANES 
Chemical and engineering bases for green H_(2)0_(2) production and related oxidation and ammoximation of olefins and analogues
《National Science Review》2024年第8期298-315,共18页Minghua Qiao Xingui Zhou Zexue Du Peng Wu Baoning Zong 
supported by the State Key Research and Development Project of China (2021YFA1501400).
Plastics,fibers and rubber are three mainstream synthetic materials that are essential to our daily lives and contribute significantly to the quality of our lives.The production of the monomers of these synthetic poly...
关键词：hydrogen peroxide OXIDATION AMMOXIMATION propylene oxide EPICHLOROHYDRIN cyclohexanone oxime 
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