This work was supported by the National Key Research and Development Project of China(No.2018YFA0703501);the National Natural science Foundation of China(Nos.22021002,21790050,21790051);the key program of the Chinese Academy of Science(No.QYZDY-SSW-SLH015);the Key Research Program of the Chinese Academy of Sciences(No.XDPB13);the Fund of K.C.Wong Education Foundation(No.GJTD-2020-02)。
Graphdiyne(GDY),a new carbon allotrope composed of sp-sp^(2) carbon atoms,has attracted increased attention in recent years.It has a direct band gap of 0.46-1.22 eV,high charge carrier mobility and lower work function...
This work was supported by the Natural Science Foundation of Shandong Province,China(No.ZR2020ZD38).
As a new carbon allotrope,graphdiyne(GDY)has shown intensive practical application prospects in the energy field,catalysis,gas separation,etc.,due to its unique 2Dπ-conjugated structure,rich sp-hybridized carbon atom...
A series of sulfenimine cephalosporin derivatives(6a--6t) was designed, synthesized and evaluated for their inhibitory activity against class A β-lactamase(TEM-1) derived from E. coli, and class C β-lactamase (...
Supported by the National Natural Science Foundation of China(Nos.20771030, 20671025).
A novel series of first procaspase activating compound(PAC-1) analogues was designed, synthesized and evaluated for antitumor activity towards two cell lines[human promyelocytic leukemia cell line(HL60) and human ...
Supported by the National Natural Science Foundation of China(No.20872069), the National Basic Research Program of China(No.2010CB 126106), the National Key Technologies R&D Program of China(No.2011BAE06B05), the Tianjin Natural Science Foundation, China(No. 11JCYBJC08600) and the Fund of State Key Laboratory of Elemento-Organic Chemistry, China.
A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, 1H nuclear magnetic resonance(IH NMR) and high...
Supported by the National Basic Research Program of China(No.2010CB126106)
Twelve novel analogues of chlorantraniliprole containing nitro group were synthesized,and their structures were characterized by 1H NMR and high-resolution mass spectrometry(HRMS).Their evaluated insecticidal activi...
Supported by the Scientific Research Foundation of Department of Education of Yunnan Province,China(No.09Y0181)
After the geometry optimization at B3LYP/6-31+G(d,p) level,the calculations of the NMR chemical shifts of a series of stilbene analogues were carried out by means of Gauge Including Atomic Orbitals(GIAO) method a...
The recombinant Saccharomyces cerevisiae strain stably expressing recombinant human glucagon-like peptide-l(rhGLP-1) analogue, as a potential oral drug delivery system for diabetes type II treatment, was successfull...
A new synthetic method and GABA transporter inhibitory activities of Tiagabine and its analogues are described. The key intermediates 4-tosyl-1,1-diaryl/heteroaryl-l-butene 10a-10e were synthesized by Wittig reaction,...
The novel 19 nor l α ,25 dihydroxy vitamin D 3 analogues possessing an ethyl at the 2 position(4 and 5), were synthesized by coupling 25 hydroxy Windaus Grundmann ketone derivative 20 with A ring syntho...