the project with number IR.SBMU.RETECH.REC.1399.024 from Student Research Committee,Department of Optometry,Faculty of Rehabilitation,Shahid Beheshti University of Medical Sciences,Tehran,Iran;the“Student Research Committee”and“Research&Technology Chancellor”in Shahid Beheshti University of Medical Sciences for their financial support of this study。
·AIM: To evaluate the efficacy and safety of intrastromal transplantation of adipose-derived stem cells(ASCs) in keratoconus patients.·METHODS: This study was conducted on 8 eyes of 8 patients with moderate to sever...
Inflammatory events in the corneal stroma may activate keratocytes and trigger their transition towards myofibroblasts,which now produce different extracellular matrix(ECM)proteins thus causing corneal opacification.C...
Supported by Natural Science Foundation of Hunan Province(No.2016JJ2163);Natural Science Foundation of Hubei Province(No.2015CFC837);Health and Family Planning Committee Science Foundation of Hubei Province(No.WJ2015MB259);Health and Family Planning Committee Science Foundation of Wuhan Municipality(No.WX17A13)
AIM: To compare the clinical and microstructural changes induced by different transepithelial iontophoresis-assisted corneal cross-linking(I-CXL) methods for keratoconus. METHODS: A total of 42 eyes of 42 patients wit...
Supported by National Natural Science Foundation of China(No.81200661);Nature Science Foundation of Hubei Province(No.2010CDB09802);Wuhan Chenguang Plan Grant(No.201150431124)
AIM: To investigate the influence of minTBP-1-PRGDN on the attachment,proliferation and collagen I synthesis of human keratocyte on titanium(Ti) surface. · METHODS: The chimeric peptide RKLPDAPRGDN(minTBP-1-PRGDN) wa...
National Natural Science Foundation of China(No.81170831)
AIM:To investigate the effects of bovine pituitary extract on the proliferation of keratocytes and maintaining the keratocyte phenotype/n v/tro.METHODS:Single keratocytes were isolated by enzyme digestion for in vitro...