supported by the National Natural Science Foundation of China,No.81171191(to LYZ);the Shenzhen Special Fund Project on Strategic Emerging Industry Development of China,No.JCYJ20160422170522075(to LYZ);the Shenzhen Healthcare Research Project of China,No.201601015(to LYZ)
Optogenetics is a combination of optics and genetics technology that can be used to activate or inhibit specific cells in tissues. It has been used to treat Parkinson’s disease, epilepsy and neurological diseases, bu...
The intricate and complex interaction between different populations of neurons in the brain has imposed limits on our ability to gain detailed understanding of synaptic transmission and its integration when employing ...
sponsored by the National Natural Science Foundation of China (General Program),No.81070749,31070882,30970758;Key Project of Chongqing Science & Technology Commission,No. 2010AB5118
Channelrhodopsin-2 ectopically expressed in the retina can recover the response to blue light in genetically blind mice and rats, but is unable to restore visual function due to optic nerve or optic tract lesions. Lon...
supported by Ralph Wilson Foundation(to A.G.H);Capita Foundation(to A.G.H)
We have delivered viral vectors containing either Chop2 fused with GFP, Channelrhodopsin-2 (ChR2), or Halorhodopsin (HaloR) fused with mCherry (to form light gated cation channels or chloride pumps, respectively...