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BACKGROUND Recent studies have shown that the tumor microenvironment significantly influences the behavior of solid tumors.In this context,Accumulated data suggests that pathological evaluation of tumor budding(TB),de...
Dr.M.Ermis and Dr.N.Falcone contributed equally to this work.The authors gratefully acknowledge the funding by the National Institutes of Health(HL140951,HL137193,CA257558,DK130566);Dr.M.Ermis acknowledges The Scientific and Technological Research Council of Turkiye for 2219-International Postdoctoral Research Fellowship Program.
The tumor microenvironment consists of diverse,complex etiological factors.The matrix component of pancreatic ductal adenocarcinoma(PDAC)plays an important role not only in physical properties such as tissue rigidity ...
Supported by National Nature Science Foundation,No.81873111,No.82174454,and No.82074182;Natural Science Foundation of Beijing,No.7202066。
Liver is the most common site of metastases of colorectal cancer,and liver metastases present with distinct histopathological growth patterns(HGPs),including desmoplastic,pushing and replacement HGPs and two rare HGPs...
supported by National Institutes of Health(Grant No.CA198999,USA);the State Key Laboratory of Molecular Engineering of Polymers,Fudan University(China);the National Natural Science Foundation of China(Grant Nos.81202924 and81773909);Shanghai Rising-Star Program of China(Grant No.13QA1403400);Shanghai talent development funds(Grant No.201665,China);Shanghai municipal commission of health and family planning(Grant No.2017YQ060,China)
Desmoplastic tumors have an abundance of stromal cells and the extracellular matrix which usually result in therapeutic resistance.Current treatment prescriptions for desmoplastic tumors are usually not sufficient to ...
Background: Desmoplastic fibroblastoma (collagenous fibroma) is an uncommon benign soft-tissue tumor, rarely involving bone. It shares some overlapping features with other infiltrate tumors, such as desmoid-type fi...
The desmoplastic ameloblastoma (DA) is a rare variant of the conventional ameloblastoma. It accounts for only 4% to 13% of all ameloblastomas. Desmoplastic ameloblastoma (DA) was included in the World Health Organizat...
Supported by University of Southern Denmark;Odense University Hospital Research Fund
Pancreatic cancer(PC) is the most aggressive type of common cancers, and in 2014, nearly 40000 patients died from the disease in the United States. Pancreatic ductal adenocarcinoma, which accounts for the majority of ...
Ameloblastoma—a benign epithelial odontogenic tumor-histologically occurs in different patterns, the most common of which are plexiform and follicular. “Hybrid” ameloblastoma is a variant in which areas of follicul...
Desmoplastic ameloblastoma(DA)is an unusual variant of ameloblastoma exhibiting important differences in the anatomical distribution,radiographic features and histologic appearance compared with the classic type of am...
Supported by Department of Pathology,the University of Texas Health Science Center at Houston,United States
Desmoplastic small round cell tumor(DSRCT) is a rare,aggressive malignant neoplasm of unknown origin, and is comprised of small round cells with a characteristic desmoplastic stroma. DSRCT typically expresses epitheli...