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作品数:35被引量:69H指数:4
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相关领域:文化科学更多>>
相关作者:加小双梁业红谢传晓李明顺张德贵更多>>
相关机构:中国人民大学中国农业科学院武汉大学更多>>
相关期刊:《Stress Biology》《US-China Foreign Language》《World Journal of Hepatology》《Bulletin of the Chinese Academy of Sciences》更多>>
相关基金:国家自然科学基金国家高技术研究发展计划The Royal Society更多>>
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Population genomics advances in frontier ethnic minorities in China
《Science China(Life Sciences)》2025年第4期961-973,共13页Hao Chen Shuhua Xu 
supported by the National Key Research and Development Program of China(2023YFC2605400);the National Natural Science Foundation of China(32030020,32288101);the Shanghai Science and Technology Commission Program(23JS1410100);the Office of Global Partnerships(Key Projects Development Fund)。
China,with its large geographic span,possesses rich genetic diversity across vast frontier regions in addition to the Han Chinese majority.Importantly,demographic events and various natural and cultural environments i...
关键词:Chinese populations ethnic minorities genetic diversity local adaptation East Asian ancestry 
DNA methylation and genetic regulation in natural populations of East Asian and mixed Eurasian ancestry
《Science Bulletin》2025年第5期638-642,共5页Shuangshuang Cheng Zhilin Ning Yan Lu Yuhan Du Xiaonan Yang Minghui Li Dilinuer Maimaitiyiming Shuhua Xu 
National Key Research and Development Program of China(2023YFC2605400);National Natural Science Foundation of China(32030020,32288101,and 32470649);Shanghai Science and Technology Commission Program(23JS1410100);Office of Global Partnerships(Key Projects Development Fund);The computational work in this study was supported by the CFFF Computing Platform of Fudan University.The funders had no role in the study design,data collection,analysis,decision to publish,or preparation of the manuscript.
References Show full outline Cited by(1)Figures(3)Unlabelled figure Fig.1.Population diversity of DNA methylation Fig.2.Genetic contribution to the population differentiation in DNA methylation…Extras(1)Supplementary...
关键词:SURGERY Eurasian MIXED 
Genetic formation of Sui populations in southwest China
《Journal of Systematics and Evolution》2024年第5期1054-1067,共14页Ming-Xia Xie Xing-Yue Hu Qi-Yang Wang Zheng Ren Yu-Bo Liu Mei-Qing Yang Xiao-Ye Jin Xiao-Min Yang Rui Wang Chuan-Chao Wang Jiang Huang 
funded by the National Natural Science Foundation of China(NSFC 82260335,32270667);the Natural Science Foundation of Fujan Province of China(No.2023J06013);Guizhou Scientific Support Project,Qian Science Support[2021]General 448;Guizhou Province Education Department,Characteristic Region Project,Qian Education KY No.[2021]065;Guizhou“Hundred”High-level Innovative Talent Project,Qian Science Platform Talents[2020]6012;Guizhou Scientific Support Project,Qian Science Support[2020]4Y057;Guizhou Science Project,Qian Science Foundation[2020]1Y353;Guizhou Scientific Support Project,Qian Science Support[2019]2825;Guizhou Scientific Cultivation Project,Qian Science Platform Talent[2018]5779-X;Guizhou Engineering Technology Research Center Project,Qian High-Tech of Development and Reform Commission No.[2016]1345;the National Social Science Foundation of Chinagranted to Chuan-Chao Wang(21&ZD285).
The Sui people living in Guizhou province have a unique ethnic culture and population history due to their long-time isolation from other populations.To investigate the genetic structure of Sui populations in differen...
关键词:admixture history ancestry inference gene chips population substructure SUI 
Type 2 diabetes across populations of different ancestry: deconstructing the genomic landscape
《Signal Transduction and Targeted Therapy》2024年第10期4157-4159,共3页Georgia Xourafa Christian Herder Michael Roden 
The research of the authors is supported in part by grants from the German Federal Ministry of Health(BMG),the Ministry of Culture and Science of the State North Rhine-Westphalia(MKW NRW)to the German Diabetes Center(DDZ)and the German Federal Ministry of Education and Research(BMBF)to German Center for Diabetes Research(DZD e.V.);The research of CH and MR is also supported in part by grants from the European Community(HORIZON-HLTH-2022-STAYHLTH-02-01:Panel A to the INTERCEPT-T2D consortium);The research of MR is further supported in part by the Schmutzler Stiftung and the program“Profilbildung 2020”,an initiative of the Ministry of Culture and Science of the State of North Rhine-Westphalia.The sole responsibility for the content of this publication lies with the authors.
In a recent study published in Nature Medicine,Smith and colleagues used data from 1.4 million individuals across 37 genome-wide association studies(GWAS)reflecting different genetic ancestral populations to identify ...
关键词:DIABETES LANDSCAPE CONSTRUCTING 
Large-scale genome-wide SNP analysis reveals the rugged(and ragged)landscape of global ancestry,phylogeny,and demographic history in chicken breeds
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第4期324-340,共17页Natalia V.DEMENTIEVA Yuri S.SHCHERBAKOV Olga I.STANISHEVSKAYA Anatoly B.VAKHRAMEEV Tatiana A.LARKINA Artem P.DYSIN Olga A.NIKOLAEVA Anna E.RYABOVA Anastasiia I.AZOVTSEVA Olga V.MITROFANOVA Grigoriy K.PEGLIVANYAN Natalia R.REINBACH Darren K.GRIFFIN Michael N.ROMANOV 
supported by the Ministry of Science and Higher Education of the Russian Federation(No.075-152021-1037,Internal No.15.BRK.21.0001)。
The worldwide chicken gene pool encompasses a remarkable,but shrinking,number of divergently selected breeds of diverse origin.This study was a large-scale genome-wide analysis of the landscape of the complex molecula...
关键词:Chicken genome diversity Single nucleotide polymorphism(SNP)analysis Gene pool Global ancestry PHYLOGENY Demographic history 
Local ancestry and selection in admixed Sanjiang cattle被引量:1
《Stress Biology》2023年第1期332-344,共13页Yang Lyu Yaxuan Ren Kaixing Qu Suolang Quji Basang Zhuzha Chuzhao Lei Ningbo Chen 
supported by the earmarked fund of the CARS-37;the National Natural Science Foundation of China(31872317)to Chuzhao Lei;the fellowship of the China Postdoctoral Science Foundation(2021T140564 and 2020M683587);Shaanxi Youth Science and Technology New Star(2022KJXX-77);the Natural Science Basic Research Program of Shaanxi(2021JQ-137);the National Natural Science Foundation of China(32102523);the Fundamental Research Funds for the Central Universities to Ningbo Chen;the Scientific Research Fund of the Department of Education of Yunnan(2022J0830)to Kaixing Qu.
The majority of native cattle are taurine×indicine cattle of diverse phenotypes in the central region of China.Sanjiang cattle,a typical breed in the central region,play a central role in human livelihood and have go...
关键词:Whole-genome sequencing Local ancestry SELECTION ADAPTATION 
Construction and evaluation of the functional polygenic risk score for gastric cancer in a prospective cohort of the European population
《Chinese Medical Journal》2023年第14期1671-1679,共9页Yuanliang Gu Caiwang Yan Tianpei Wang Beiping Hu Meng Zhu Guangfu Jin 
supported by grants from the National Natural Science Foundation of China(Nos.82125033,82230110,81872702,82003534,and 82273714);the Natural Science Foundation of Jiangsu Province(No.BK20200674);CAMS Innovation Fund for Medical Sciences(No.2019RU038).
Background:A polygenic risk score(PRS)derived from 112 single-nucleotide polymorphisms(SNPs)for gastric cancer has been reported in Chinese populations(PRS-112).However,its performance in other populations is unknown....
关键词:Polygenic risk score Gastric cancer Polymorphism single nucleotide Cross ancestry 
Associations between Avocado Intake and Lower Rates of Incident Type 2 Diabetes in US Adults with Hispanic/Latino Ancestry
《Journal of Diabetes Mellitus》2023年第2期116-129,共14页Alexis C. Wood Mackenzie K. Senn Jerome I. Rotter 
Background/Purpose: Hispanic/Latinos in the US are at increased risk for type 2 diabetes (T2D). Data suggest that avocado intake is associated with better glycemic control, but whether this translates to protection fr...
关键词:AVOCADO Diet Type 2 Diabetes DYSGLYCEMIA Monounsaturated Fats 
Genetic diversity and inferred ancestry of Asian lotus(Nelumbo nucifera) germplasms in Thailand and Vietnam
《Plant Diversity》2023年第1期69-79,共11页Feng-Luan Liu Ya-Lan Dai Thi Nga Hoang Vichai Puripunyavanich Primlarp Wasuwat Chukiatman Mi Qin Yan-Rong Fu Yu-Chu Chen Dai-Ke Tian 
supported by Shanghai Landscaping Administration Bureau (Grant number G182412);the grant from Zhejiang Humanity Landscape Co.,Ltd.,Hangzhou,China。
Tropical lotus(Nelumbo) is an important and unique ecological type of lotus germplasm.Understanding the genetic relationship and diversity of the tropical lotus is necessary for its sustainable conservation and utiliz...
关键词:Aquatic plant Asian lotus EST-SSR NELUMBO Southeast Asia Tropical lotus 
The Probability of Pairwise Shared Ancestry and the Expected Number of Pairs of k-th Cousins in a Population Sample
《Natural Science》2022年第11期472-482,共11页Philip M. Service 
An analytical solution is derived for the probability that a random pair of individuals from a panmictic population of size N will share ancestors who lived G generations previously. The analysis is extended to obtain...
关键词:Pairwise Shared Ancestry Simulation Denmark Number of Cousins Population Sample Population Structure 
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