National Natural Science Foundation of China(Grant No.81373343);the Key Grant of Beijing Natural Science Foundation(Grant No.7131009)
Triple-negative breast cancer is the tumor that lacks expressions of estrogen receptor(ER), progesterone receptor(PR) and human epidermal growth factor receptor-2(HER2). A regular chemotherapy cannot eradicate t...
Eleventh Five-Year Plan for National Science and Technology Major Project(Grant No.2009ZX0930-010);National Science Foundation of China(Grant No.81172915);a grant from Major New Drugs Research and Development Platform of Peking University(Grant No.2009ZX09301-010)
YSY-01A has shown proliferation inhibitory activity to certain types of tumor cells by inhibiting proteasome. How- ever, its effect on autophagy, which is related with the ubiquitin proteasome pathway (UPP), remains...
The differentially expressed proteins between normal and tamoxifen-induced autophagic MCF-7 cells were studied by 2-DE combining with mass spectrometric analysis.Totally,there were 668±99 and 550±97 protein spots de...