THIORIDAZINE

作品数：4被引量：0H指数：0
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相关领域：医药卫生更多>>
相关作者：陈姿颖黄莉朱荣华陈远光更多>>
相关机构：北京协和医学院湖南医科大学台湾大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Biosafety and Health》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金更多>>
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Thioridazine reverses trastuzumab resistance in gastric cancer by inhibiting S-phase kinase associated protein 2-mediated aerobic glycolysis
《World Journal of Gastroenterology》2023年第45期5974-5987,共14页Zheng-Yan Yang Yi-Wei Zhao Jing-Rui Xue Ran Guo Zhi Zhao Han-Di Liu Zhi-Guang Ren Ming Shi 
Supported by Youth Fund of National Natural Science Foundation of China,No.81803575,No.31902287;Kaifeng Science and Technology Development Plan Project,No.2203008;Key Specialized Research and Promotion Project of Henan Province in 2023,No.232102311205;Henan Medical Science and Technology Research Program Project,No.LHGJ20210801;College Students Innovation and Entrepreneurship Training Program of Henan University,No.20231022007.
BACKGROUND Trastuzumab constitutes the fundamental component of initial therapy for patients with advanced human epidermal growth factor receptor 2(HER-2)-positive gastric cancer(GC).However,the efficacy of this treat...
关键词：Gastric cancer Trastuzumab resistance THIORIDAZINE S-phase kinase associated protein 2 GLYCOLYSIS 
Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation
《Acta Pharmacologica Sinica》2023年第10期1977-1988,共12页Min-chun Jiang Huan-yu Ding Yu-hong Huang Chak Kwong Cheng Chi Wai Lau Yin Xia Xiao-qiang Yao Li Wang Yu Huang 
supported by Hong Kong Research Grants Council(SRFS2021-4S04,14112919,14164817,14109720);Hong Kong PhD Fellowship Scheme,and Health and Medical Research Fund(07181286)of China.
Atherosclerotic diseases remain the leading cause of adult mortality and impose heavy burdens on health systems globally. Our previous study found that disturbed flow enhanced YAP activity to provoke endothelial activ...
关键词：ATHEROSCLEROSIS ENDOTHELIUM INFLAMMATION disturbed flow Yes-associated protein THIORIDAZINE 
Screening for inhibitors against SARS-CoV-2 and its variants
《Biosafety and Health》2022年第3期186-192,共7页Weijing Yuan Xiaojing Dong Lan Chen Xiaobo Lei Zhuo Zhou Li Guo Jianwei Wang 
supported by grants from National Key R&D Program of China(2020YFA0707600 to Z.Z.and X.L.);the National Natural Science Foundation of China(81930063 and 81971948 to J.W.and X.L.);hinese Academy of Medical Science(CAMS)Innovation Fund for Medical Sciences(2021-I2M-1-038 to J.W.)。
Severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)continues to evolve,generating new variants that pose a threat to global health;therefore,it is imperative to obtain safe and broad‐spectrum antivirals aga...
关键词：SARS‐CoV‐2 Delta variant Omicron variant Trifluoperazine 2HCl Thioridazine HCl Antiviral therapy 
Determination of Thioridazine in Plasma by HighPerformance Liquid Chromatography
《Journal of Chinese Pharmaceutical Sciences》1995年第1期37-40,共4页黄莉 朱荣华 陈远光 
用高效液相色谱法测定人血浆中甲硫哒嗪的浓度。以氯氮平为内标，标本在碱性条件下用叔丁基甲醚（叔丁基甲醚与异丙醇之比为６０：１，ｖ／ｖ）提取，流动相为甲醇：水（７５：２５，内含四甲基乙二胺、冰醋酸分别为０．４５％，０．３...
关键词：THIORIDAZINE HPLC 
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