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Effect of diabetes mellitus on antibody levels in elderly individuals after vaccination with inactivated SARS-CoV-2 vaccine
《感染控制(英文)》2024年第1期60-67,共8页Wen Guo Yu Cao Yingmei Feng 
Background We explored the influence of diabetes on the antibody levels of elderly individuals after inoculation with an inactivated vaccine against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and the f...
关键词：inactivated vaccine against SARS-CoV-2 DIABETES IgG antibody neutralizing antibody 
Safety and Immunogenicity After Primary and Booster Inactivated SARS-Cov-2 Vaccination in Patients with Autoimmune Liver Diseases
《Journal of Clinical and Translational Hepatology》2024年第2期162-171,共10页Zhiwei Chen Yuting Wang Taiyu He Hu Li Ling Ao Qingbo Pan Yingzhi Zhou Qian Zhu Dejuan Xiang Gaoli Zhang Ning Ling Min Chen Peng Hu Mingli Peng Dachuan Cai Dazhi Zhang Hong Ren 
supported by the National Science and Technology Major Project of China(Nos 2017ZX10202203-007,2017ZX10202203-008,2018ZX10302206-003)and a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis.We also acknowledge the support of the National Natural Science Foundation of China(No 81772198);Natural Science Foundation of Chongqing,China(No.cstc2020jcyjmsxmX0389).
Background and Aims:SARS-CoV-2 vaccines-associated autoimmune liver diseases have been reported in several case reports.However,the safety and immunogenicity after primary and booster inactivated SARS-CoV-2 vaccinatio...
关键词：SARS-CoV-2 Autoimmune liver disease Inactivated SARS-CoV-2 vaccine SAFETY Antibody responses Memory B cells 
Inactivated SARS-CoV-2 booster vaccine enhanced immune responses in patients with chronic liver diseases
《Virologica Sinica》2023年第5期723-734,共12页Yongmei Liu Jianhua Lu Haoting Zhan Wenfang Yuan Xiaomeng Li Haiyan Kang Haolong Li Yongliang Chen Linlin Cheng Xingli Sun Haojie Zheng Wei Wang Erhei Dai Yongzhe Li 
This work was supported by the Beijing Natural Science Foundation(M23008);the National Key Research and Development Program of China(2018YFE0207300);Beijing Municipal Science&Technology Commission(Z211100002521021);the National High Level Hospital Clinical Research Funding(2022-PUMCH-B-124);Key Research and Development Plan of Hebei Province,Special Health Innovation Project(22377744D).
Chronic liver disease(CLD)entails elevated risk of COVID-19 severity and mortality.The effectiveness of the booster dose of inactivated SARS-CoV-2 vaccine in stimulating antibody response in CLD patients is unclear.Th...
关键词：Chronic liver disease(CLD) SARS-CoV-2 inactivated vaccines Booster vaccination Antibody response Immune response 
Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination among COVID-19 convalescents
《Frontiers of Medicine》2023年第4期747-757,共11页Hao Wang Yu Yuan Bihao Wu Mingzhong Xiao Zhen Wang Tingyue Diao Rui Zeng Li Chen Yanshou Lei Pinpin Long Yi Guo Xuefeng Lai Yuying Wen Wenhui Li Hao Cai Lulu Song Wei Ni Youyun Zhao Kani Ouyang Jingzhi Wang Qi Wang Li Liu Chaolong Wang An Pan Xiaodong Li Rui Gong Tangchun Wu 
supported by the Emergency Key Program of Guangzhou Laboratory(No.EKPG21-30);the Fundamental Research Funds for the Central Universities(No.2019kfyXMBZ015);the Fellowship of China Postdoctoral Science Foundation(Nos.2020T130034ZX and 2020M680102);the National Natural Science Foundation of China(Nos.72061137006 and 82204113).
Emerging SARS-CoV-2 variants have made COVID-19 convalescents susceptible to re-infection and have raised concern about the efficacy of inactivated vaccination in neutralization against emerging variants and antigen-s...
关键词：COVID-19 convalescent SARS-CoV-2 inactivated vaccination neutralizing antibody B cell response 
Effects of specific doses of E-beam irradiation which inactivated SARS-CoV-2 on the nutrition and quality of Atlantic salmon被引量：1
《Food Science and Human Wellness》2023年第4期1351-1358,共8页Huilin Yu Junhui Zhang Yan Zhao Honghao Li Yixuan Chen Jiajin Zhu 
the grants from Hangzhou Global Scientific and Technological Innovation Center of Zhejiang University(KC2021ZY0B0003).
The contamination of Atlantic salmon with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has impeded the development of the cold-chain food industry and posed possible risks to the population.Electron beam...
关键词：E-beam irradiation Atlantic salmon SARS-CoV-2 Physicochemical properties 
Dynamic Humoral Immune Response to Primary and Booster Inactivated SARS-CoV-2 Vaccination in Patients with Cirrhosis
《Journal of Clinical and Translational Hepatology》2023年第7期1476-1484,共9页Qian Zhu Lu Wang Xiaoxiao Hu Yingzhi Zhang Tianquan Huang Taiyu He Zhiwei Chen Gaoli Zhang Mingli Peng Min Chen Dachuan Cai Xiaofeng Shi Hong Ren 
supported by the National Science and Technology Major Project of China(2017ZX10202203-007,2017 ZX10202203-008,2018ZX10302206-003);Remarkable Innovation-Clinical Research Project,The Second Affiliated Hospital of Chongqing Medical University and The First batch of key Disciplines On Public Health in Chongqing;support of the National Natural Science Foundation of China(81772198);Natural Science Foundation of Chongqing,China(cstc2020jcyj-msxmX0389).
Background and Aims:Our aim was to determine the immune efficacy of a severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)booster vaccination in cirrhotic patients who had received the primary series.Methods:We...
关键词：SARS-CoV-2 Omicron subvariants CIRRHOSIS Booster dose Humoral response 
Role of inactivated SARS-CoV-2 vaccine induced T cell responses in ameliorating COVID-19 severity被引量：1
《Virologica Sinica》2023年第2期324-326,共3页Hongming Huang Jia Liu 
supported by grants from the National Natural Science Foundation of China(82172256,92169105,81861138044,and M-0060);the National Scientific and Technological Major Project of China(2017ZX10202203);the Sino-German Virtual Institute for Viral Immunology.
The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccine is one of the most effective weapons to fight the coronavirus disease 2019(COVID-19)pandemic(Lazarus et al.,2022).Among all SARS-CoV-2 vaccines ge...
关键词：VACCINE SEVERITY ACUTE 
An inactivated recombinant rabies virus chimerically expressed RBD induces humoral and cellular immunity against SARS-CoV-2 and RABV被引量：2
《Virologica Sinica》2023年第2期244-256,共13页Haili Zhang Hongli Jin Feihu Yan Yumeng Song Jiaxin Dai Cuicui Jiao Yujie Bai Jingxuan Sun Di Liu Shen Wang Mengyao Zhang Jilong Lu Jingbo Huang Pei Huang Yuanyuan Li Xianzhu Xia Hualei Wang 
funded by the National Key Research and Development Program of China(grant No.2021YFC2600202);the National Natural Science Foundation of China(grant numbers 31872487).
Many studies suggest that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can infect various animals and transmit among animals,and even to humans,posing a threat to humans and animals.There is an urgent ne...
关键词：SARS-CoV-2 Vaccine RBD Chimeric expression RABV 
Weakened humoral immune responses of inactivated SARS-CoV-2 vaccines in patients with solid tumors被引量：1
《Cancer Communications》2023年第2期280-284,共5页Zhiwei Chen Peng Zhu Zuojin Liu Bin Zhu Guobing Yin Jia Ming Rui Song Qingbo Pan Tong Li Xingwei Jiang Bing Wang Shuaibin Liu Hongxing Cai Jingjie Wang Yuling Han Zijing Lin Yang Hong Min Chen Mingli Peng Lina Hu Dachuan Cai Hong Ren 
the Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University and conformed with the ethical guidelines of the Declaration of Helsinki(Ratification No.133/2022);Written informed consentwas obtained fromall the participants.This study has been registered at ClinicalTrials.gov(NCT05043246).
Dear Editor Coronavirus disease 19(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),remains a pandemic.Cancer patients have a higher risk of poor outcomes for SARS-CoV-2 infection than t...
关键词：PATIENTS vaccines HUMORAL 
Protection from infection or disease? Re-evaluating the broad immunogenicity of inactivated SARS-CoV-2 vaccines
《Virologica Sinica》2022年第6期783-785,共3页Anthony T.Tan Joey Ming Er Lim Antonio Bertoletti 
supported by the Singapore Ministry of Health’s National Medical Research Council MOH-000019(MOH-Sta R17Nov-0001) grant
How do we measure vaccine efficacy? The strictest but also easiest parameter to determine vaccine efficacy is its ability to block infection.Indeed, if a vaccine is able to block infection, this necessarily follows th...
关键词：VACCINE INFECTION vaccines 
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