INACTIVATED

作品数：113被引量：206H指数：7
导出分析报告
相关领域：医药卫生更多>>
相关作者：刘芳任爱国何志义马俊荣徐应军更多>>
相关机构：华北煤炭医学院中国预防医学科学院中国医科大学附属第一医院华中农业大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家高技术研究发展计划重庆市自然科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 学科=医药卫生—基础医学x
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Generation of inactivated IL2RG and RAG1 monkeys with severe combined immunodeficiency using base editing
《Signal Transduction and Targeted Therapy》2023年第10期4825-4837,共13页Xiao Zheng Chunhui Huang Yingqi Lin Bofeng Han Yizhi Chen Caijuan Li Jiawei Li Yongyan Ding Xichen Song Wei Wang Weien Liang Jianhao Wu Jiaxi Wu Jiale Gao Chengxi Wei Xudong Zhang Zhuchi Tu Sen Yan 
This work was supported by the National Key Research and Development Program of China(2021YFA0805300,2021YFA0805204);the National Natural Science Foundation of China(82171244,81922026,32170981);Guangzhou Key Research Program on Brain Science(202007030008).
Severe combined immunodeficiency(SCiD)encompasses a range of inherited disorders that lead to a profound deterioration of the immune system.Among the pivotal genes associated with SCID,RAG1 and IL2RG play crucial role...
关键词：IMMUNODEFICIENCY IMMUNITY RAG1 
Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination among COVID-19 convalescents
《Frontiers of Medicine》2023年第4期747-757,共11页Hao Wang Yu Yuan Bihao Wu Mingzhong Xiao Zhen Wang Tingyue Diao Rui Zeng Li Chen Yanshou Lei Pinpin Long Yi Guo Xuefeng Lai Yuying Wen Wenhui Li Hao Cai Lulu Song Wei Ni Youyun Zhao Kani Ouyang Jingzhi Wang Qi Wang Li Liu Chaolong Wang An Pan Xiaodong Li Rui Gong Tangchun Wu 
supported by the Emergency Key Program of Guangzhou Laboratory(No.EKPG21-30);the Fundamental Research Funds for the Central Universities(No.2019kfyXMBZ015);the Fellowship of China Postdoctoral Science Foundation(Nos.2020T130034ZX and 2020M680102);the National Natural Science Foundation of China(Nos.72061137006 and 82204113).
Emerging SARS-CoV-2 variants have made COVID-19 convalescents susceptible to re-infection and have raised concern about the efficacy of inactivated vaccination in neutralization against emerging variants and antigen-s...
关键词：COVID-19 convalescent SARS-CoV-2 inactivated vaccination neutralizing antibody B cell response 
Delta(B.1.617.2)inactivated vaccine candidate elicited neutralizing antibodies to SARS-CoV-2 and circulating variants in rhesus macaques
《Virologica Sinica》2023年第4期627-630,共4页Yanjun Zhang Haiyan Mao Ju Li Jianhua Li Chen Huang Jiaxuan Li Minglei Chu Fengbo Xue Linhui Wang Zhongbiao Fang Zhen Wang Jinan Wu Keda Chen 
supported by the Science and Technology Program of Zhejiang Province (#2022C03017);Key Research and Development Program of Zhejiang Province (#2021C03044);Major Health Science and Technology Projects of Zhejiang Province (#WKJ-ZJ-2105);National Key R&D Program of China (#2021YFC2301200).
Dear Editor,The coronavirus disease 2019(COVID-19)pandemic has resulted in 763 million cases and over 6 million deaths as of April 2023.Given the high prevalence and widespread distribution of coronaviruses,the geneti...
关键词：ANTIBODIES VACCINE 
Immunosuppressive therapy selectively modulates B-cell responses in patients with rheumatic and musculoskeletal diseases receiving the inactivated COVID-19 vaccine
《Rheumatology & Autoimmunity》2023年第2期78-89,共12页Rui Li Ruru Guo Jia Li Bing Zheng Ronghao Xu Xiaoyue Jiang Yingying Chen Guo Tang Qianqian Li Yixuan Li Jiaqi Feng Xiaoxiang Chen Ying Wang Shuang Ye Fang Du Liangjing Lu Jun Deng 
National Natural Science Foundation of China,Grant/Award Numbers:82271784,81974251,82071816;National Key Research and Development Program of China,Grant/Award Number:2017YFC0909002。
Background:Immunosuppressive medication reduces the immunogenicity of the coronavirus disease 2019(COVID-19)vaccines in patients with rheumatic and musculoskeletal diseases(RMDs).However,the underlying mechanism remai...
关键词：COVID-19 vaccination humoral and cellular responses immunosuppressive medication rheumatic and musculoskeletal diseases 
An inactivated recombinant rabies virus chimerically expressed RBD induces humoral and cellular immunity against SARS-CoV-2 and RABV被引量：2
《Virologica Sinica》2023年第2期244-256,共13页Haili Zhang Hongli Jin Feihu Yan Yumeng Song Jiaxin Dai Cuicui Jiao Yujie Bai Jingxuan Sun Di Liu Shen Wang Mengyao Zhang Jilong Lu Jingbo Huang Pei Huang Yuanyuan Li Xianzhu Xia Hualei Wang 
funded by the National Key Research and Development Program of China(grant No.2021YFC2600202);the National Natural Science Foundation of China(grant numbers 31872487).
Many studies suggest that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can infect various animals and transmit among animals,and even to humans,posing a threat to humans and animals.There is an urgent ne...
关键词：SARS-CoV-2 Vaccine RBD Chimeric expression RABV 
Weakened humoral immune responses of inactivated SARS-CoV-2 vaccines in patients with solid tumors被引量：1
《Cancer Communications》2023年第2期280-284,共5页Zhiwei Chen Peng Zhu Zuojin Liu Bin Zhu Guobing Yin Jia Ming Rui Song Qingbo Pan Tong Li Xingwei Jiang Bing Wang Shuaibin Liu Hongxing Cai Jingjie Wang Yuling Han Zijing Lin Yang Hong Min Chen Mingli Peng Lina Hu Dachuan Cai Hong Ren 
the Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University and conformed with the ethical guidelines of the Declaration of Helsinki(Ratification No.133/2022);Written informed consentwas obtained fromall the participants.This study has been registered at ClinicalTrials.gov(NCT05043246).
Dear Editor Coronavirus disease 19(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),remains a pandemic.Cancer patients have a higher risk of poor outcomes for SARS-CoV-2 infection than t...
关键词：PATIENTS vaccines HUMORAL 
Anti-leucine-rich glioma inactivated protein 1 encephalitis with sleep disturbance as the first symptom: A case report and review of literature被引量：2
《World Journal of Clinical Cases》2023年第2期408-416,共9页De-Lian Kong 
BACKGROUND Anti-leucine-rich glioma inactivated protein 1(anti-LGI1) encephalitis is an infrequent type of autoimmune encephalitis(AE) characterized by acute or subacute cognitive and psychiatric disturbance, facio-br...
关键词：Leucine-rich glioma inactivated 1 antibody Autoimmune encephalitis Sleep disturbance Seizures Facio-brachial dystonic seizures Case report 
Epidemiological survey and genetic characterization of type 3 vaccine-derived poliovirus isolated from a patient with four doses of inactivated polio vaccine in Henan Province,China被引量：1
《Infectious Diseases of Poverty》2022年第6期99-100,共2页Mingyu Zhang Jianhui Yang Yiran Bai Hui Zhu Changshuang Wang Lu Zhang Jin Xu Mingxia Lu Xiaoxiao Zhang Zhanpei Xiao Yating Ma Yan Wang Xiaolei Li Dongyan Wang Shuangli Zhu Dongmei Yan Wenbo Xu Yong Zhang Yanyang Zhang 
Background:Vaccine-derived poliovirus(VDPV)is a potential threat to polio eradication because they can reintroduce into the general population and cause paralytic polio outbreaks,a phenomenon that has recently emerged...
关键词：Epidemiological Survey Genetic characterization Type 3 vaccine-derived poliovirus Recombination HENAN China 
A third high dose of inactivated COVID-19 vaccine induces higher neutralizing antibodies in humans against the Delta and Omicron variants:a Randomized,Double-Blinded Clinical Trial被引量：3
《Science China(Life Sciences)》2022年第8期1677-1679,共3页Yu Cao Xiaoli Wang Siqi Li Yuan Dong Yonghong Liu Jing Li Yanqing Zhao Yingmei Feng 
supported by grants from the Beijing Science Foundation of China(Z201100005520062 and Z201100007920017)。
Dear Editor,The current pandemic of coronavirus disease 2019(COVID-19),caused by infection with severe acute respiratory syndrome coronavirus-2(SARS-Co V-2),has been ongoing for over 2 years.Like other viruses,SARS-Co...
关键词：acute respiratory ANTIBODIES 
Waning humoral immune responses to inactivated SARS-CoV-2 vaccines in patients with severe liver disease被引量：2
《Signal Transduction and Targeted Therapy》2022年第7期2138-2140,共3页Zhiwei Chen Yingzhi Zhang Rui Song Lu Wang Xiaoxiao Hu Hu Li Dachuan Cai Peng Hu Xiaofeng Shi Hong Ren 
supported by the National Science and Technology Major Project of China(2017ZX10202203-007,2017ZX10202203-008,2018ZX10302206-003);a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis;support of the National Natural Science Foundation of China(81772198),Natural Science Foundation of Chongqing,China(cstc2020jcyj-msxmX0389).
Dear Editor,The Coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is still ongoing around the world.Patients with severe liver disease(SLD),such as compens...
关键词：PATIENTS vaccines PREVENTION 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部