As Tang states,according to the theory of the fetal origins of health and disease,the mechanisms driving in utero programming as it relates to impaired organogenesis are being unraveled but remain complex[1].Maternal ...
supported by the Ministry of Science and Technology of China(2022YFC2702200,2021YFA1102900);the National Natural Science Foundation of China(Grant Nos.82022027,32270909,31721003,92168205,31871448,31820103009,and 32300684);supported by the key project of the Science and Technology of Shanghai Municipality(19JC1415300 and 21JC1405500);the Shanghai Municipal Medical and Health Discipline Construction Projects(2017ZZ02015);China Postdoctoral Science Foundation(2023M732660);the Postdoctoral Fellowship Program of CPSF(GZB20230523);Shanghai Municipal Health(Grant No.20214Y0254);Shanghai Pilot Program for Basic Research,Shanghai“Medical Academy Rising Star”Young Medical Talents Program,Shanghai First Maternity and Infant Hospital“Talent Reservoir”Sailing Program and the Fundamental Research Funds for the Central Universities.
The current coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus(SARS-CoV-2)remains a threat to pregnant women.However,the impact of early pregnancy SARS-CoV-2 infection o...
supported by the National Natural Science Foundation of China(82073573 to ZZY,U21A20523 to HYH);the Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease(BZ0308 to HYH);the National Key Research and Development Program of China(2022YFC3703502 to LJ).
Background Evidence remains limited on the association between maternal ozone(O,)exposure and congenital heart defects(CHDs)in offspring,and few studies have investigated the interaction and modification of paternal s...
supported by the Key R&D Projects of Shaanxi Province(No.2021SF-005);the Youth Independent Innovation Project of Tangdu Hospital(No.2023BTDQN020)
Normal pregnancy is a contradictory and complicated physiological process.Although the fetus carries the human leukocyte antigen(HLA)inherited from the paternal line,it does not cause maternal immune rejection.As the ...
Background: Eclampsia is responsible for over 50,000 maternal deaths with incidence of 1 death in about 100 - 1500 deliveries in developing nations. In sub-Saharan Africa, Nigeria accounts for the highest maternal mor...
National Natural Science Foundation of China(No.81960283,82072880)。
Co-signaling molecules are molecules whose ligands on the surface of cells interact with receptors on the surface of T cells to convey stimulatory or inhibitory signals to regulate immune responses.Co-signaling molecu...
Background After the global elimination of smallpox,monkeypox has become the most threatening orthopoxvirus to human health.Very few studies have been reported on pregnant women and newborns.In the case of monkeypox i...
The Natural Science Foundation of China(Nos.22022612,41877375,22036004,and 21677184);Natural Science Foundation of Guangdong Province,China(No.2020A0104006 and No.2021A1515010243);the Guangdong Provincial Key Laboratory Project(2019B121203011)for their partial research support.
Despite high production and usage,little is known about exposure to bisphenol diglycidyl ethers(BDGEs)and their derivatives in pregnant women and fetuses.In this study,we determined nine BDGEs in 106 paired maternal a...
Background: CT in pregnant patients requires careful consideration of the radiation dose and corresponding radiation risks from ionizing radiation to the unborn child. The determination of foetal dose in diagnostic ra...
supported by the National Key R&D Program of China (2018YFC1003900);the National Natural Science Foundation of China (Grant Number 82001653 to LZ and 31970828 to XW);Jiangsu Outstanding Young Investigator Program (BK20200030).
Regulatory T cells(Tregs)are fundamentally important for maintaining systemic immune homeostasis and are also required for immune tolerance at the maternal-fetal interface during pregnancy.Recent studies have suggeste...