supported by the National Natural Science Foundation of China(32371030,82071395);Natural Science Foundation of Chongqing(CSTB2024NSCQ-LZX0008);Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202300424);CQMU Program for Youth Innovation in Future Medicine(W0044)。
Maternal sleep deprivation(MSD)has emerged as a significant public health concern,yet its effects on offspring metabolism remain poorly understood.This study investigated the metabolomic implications of MSD on offspri...
supported by the National R&D program of China(2022YFC2703500);the Science and Technology Program of Guangzhou,China(202201020292 and 2023A03J0258);the Natural Science Foundation of Shandong Province(ZR2021ZD33);the Strategic Collaborative Research Program of the Ferring Institute of Reproductive Medicine,Ferring Pharmaceuticals and Chinese Academy of Sciences(FIRMC181101).
Environmental factors such as diet and lifestyle can influence the health of both mothers and offspring.However,its transgenerational transmission and underlying mechanisms remain largely unknown.Here,using a maternal...
supported by the National Natural Science Foundation of China(41925009,32100488);National Key R&D Program of China(2022YFE0203800);Chinese Academy of Sciences(YSBR-019);New Cornerstone Science Foundation through the XPLORER PRIZE。
DEAR EDITOR,The Laosicheng site in Yongshun County,Hunan Province,China,plays an important role in elucidating the animal population composition of the region prior to the middle Qing Dynasty(approximately 300 years a...
funded by the National Key Research and Development Program of China(2021YFF1000701);the Young S&T Talent Training Program of Guangdong Provincial Association for S&T,China(SKXRC202205);the Foundation for the Creative Team and Key Laboratory in Higher Education of Guangdong(2019KCXTD006 and 2019KSYS011);the National Natural Science Foundations of China(31961133031)。
Sheep have been one of the most important groups of animals since ancient times.However,the knowledge of their migration routes and genetic relationships is still poorly understood.To investigate sheep maternal migrat...
supported by the National Key R&D Program of China(2021YFC1523600);the Chinese Academy of Sciences(CAS)(YSBR-019 and XDB26000000);the National Natural Science Foundation of China(41925009);“Research on the roots of Chinese civilization”of Zhengzhou University(XKZDJC202006);the Tencent Foundation(through the XPLORER PRIZE),and the Howard Hughes Medical Institute(55008731);X.W.was supported by Key National Social Science Foundation of China(16ZDA144).
The settlement of the Tibetan Plateau epitomizes human adaptation to a high-altitude environment that poses great challenges to human activity.Here,we reconstruct a 4000-year maternal genetic history of Tibetans using...
The Provincial Administration of Arezzo and the Italian Ministry of Education,University and Research(PRIN 2010-2011,20108 TZKHC);financially and logistically supported the research.M.A.was financed by the Fondo di Ateneo per la Ricerca 2020'of the University of Sassari.
One of the factors facilitating the expansion and proliferation of wild boar Sus scrofa is the plasticity of its reproductive biology.Nevertheless,the real influence of maternal and environmental factors on number and...
supported by the National Science Foundation of China(32001551 and 31771808);the China Postdoctoral Science Foundation(2020M680779);the Agricultural Science and Technology Innovation Program of the CAAS(S2022ZD03);Hainan Yazhou Bay Seed Laboratory(B21HJ0215).
Clustered regularly interspaced short palindromic repeats(CRISPR)-Cas systems can be engineered as programmable transcription factors to either activate(CRISPRa)or inhibit transcription.Apomixis is extremely valuable ...
supported by the National Natural Science Foundation of China(grants 32130031 and 32000248);the Major Project of Hubei Hongshan Laboratory(2022hszd017);the China Postdoctoral Science Foundation(grants 2021M702525 and BX20200256).
Crop breeding schemes can be significantly accelerated by using(doubled)haploid plants.In vivo haploid induction has been applied in plant breeding for decades but is still not available for all crops and genotypes,an...
supported by Singapore Food Story R&D Programme(SFS_RND_SUFP_001_04)and the Reimagine Research Grant from the National University of Singapore.We apologize to authors whose excellent work could not be cited owing to space limitations.
Angiosperms produce seeds with two zygotic tissues,namely the embryo and endosperm,from a unique double fertilization process.Seed development occurs within the maternal tissue and relies on maternal resources.Paterna...
supported by the National Key R&D Program of China(2017YFC1002003);the project sponsored by the National Natural Science Foundation of China(31601197)。
The Dux gene plays an important role in mouse embryo development(De Iaco et al.,2017;Hendrickson et al.,2017;Whiddon et al.,2017).It participates in the maternal-to-zygotic transition(MTZ),which mainly includes matern...