DNAMETHYLATION

作品数：8被引量：32H指数：3
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相关领域：医药卫生更多>>
相关作者：冯继锋更多>>
相关机构：江苏省肿瘤医院更多>>
相关期刊：《National Science Review》《Acta Biochimica et Biophysica Sinica》《Advances in Breast Cancer Research》《World Journal of Stem Cells》更多>>
相关基金：国家自然科学基金俄罗斯基础研究基金更多>>
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The transgenerational effects of maternal low-protein diet during lactation on offspring
《Journal of Genetics and Genomics》2024年第8期824-835,共12页Lin-Jian Gu Li Li Qian-Nan Li Ke Xu Wei Yue Jing-Yi Qiao Tie-Gang Meng Ming-Zhe Dong Wen-Long Lei Jia-Ni Guo Zhen-Bo Wang Qing-Yuan Sun 
supported by the National R&D program of China(2022YFC2703500);the Science and Technology Program of Guangzhou,China(202201020292 and 2023A03J0258);the Natural Science Foundation of Shandong Province(ZR2021ZD33);the Strategic Collaborative Research Program of the Ferring Institute of Reproductive Medicine,Ferring Pharmaceuticals and Chinese Academy of Sciences(FIRMC181101).
Environmental factors such as diet and lifestyle can influence the health of both mothers and offspring.However,its transgenerational transmission and underlying mechanisms remain largely unknown.Here,using a maternal...
关键词：Lactationdiet Maternal low-proteindiet DNAMETHYLATION Transgenerational effect OOCYTE 
Two imprinted genes primed by DEMETER in the central cell and activated by WRKY10 in the endosperm
《Journal of Genetics and Genomics》2024年第8期855-865,共11页Ke Yang Yuling Tang Yue Li Wenbin Guo Zhengdao Hu Xuanpeng Wang Frédéric Berger Jing Li 
supported by the National Natural Science Foundation of China(31570322)。
The early development of the endosperm is crucial for balancing the allocation of maternal nutrients to offspring.This process is believed to be evolutionarily associated with genomic imprinting,resulting in parentall...
关键词：IMPRINTING EPIGENETICS DNAMETHYLATION Seedsize ENDOSPERM 
Investigation of DNAmethylation of TWIST Gene in Breast Cancer and Its Relationship to Histopathological Features
《Advances in Breast Cancer Research》2019年第1期45-59,共15页Onur Eroglu Oguz Cilingir Sevilhan Artan Beyhan Durak Aras 
BACKGROUND: Promoter hypermethylation and global hypomethylation in the human genome are hallmarks of most cancers. OBJECTIVE: The aim of this study is to assess the methylation profile patterns of TWIST gene and to i...
关键词：BREAST Cancer METHYLATION MS-HRM TWIST 
Non-coding RNAs and Their Roles in Stress Response in Plants被引量：9
《Genomics, Proteomics & Bioinformatics》2017年第5期301-312,共12页jingjing wang xianwen meng oxana b.dobrovolskaya yuriy l.orlov ming chen 
supported by the National Natural Science Foundation of China(Grant Nos.31611130033,31371328,and 31571366);Russian Foundation for Basic Research(Grant No.16-54-53064 and 15-04-05371)to OBD;ICG SB RAS Budget Project(Grant No.0324-2016-0008)to YLO;China Scholarship Council&Deutscher Akademischer Austauschdienst(CSC&DAAD;Project-based Personnel Exchange Program;Grant No.57136444);Science Technology Department of Zhejiang Province,China(Grant No.2015C32057)
Eukaryotic genomes encode thousands of non-coding RNAs （ncRNAs）, which play cru- cial roles in transcriptional and post-transcriptional regulation of gene expression. Accumulating evidence indicates that ncRNAs, esp...
关键词：lncRNA MIRNA Stress response RNA-directed DNAmethylation Small RNA 
DNA Methylation and Birth Weight: a Genome-wide Analysis
《Biomedical and Environmental Sciences》2017年第9期667-670,共4页MAO Li Li XIAO Xin Hua ZHANG Qian ZHENG Jia LI Wen Hui YU Miao ZHANG Hua Bing PING Fan XU Jian Ping WANG Xiao Jing 
supported by the National Natural Science Foundation of China(NSFC),project number is 81170736 and 81570715
The study illustrate the inner correlation between global DNA methylation variation and different birth weights. Infant birth weight was used to identify cases and controls. Cord blood and placentas were collected. We...
关键词：DNA Methylation and Birth Weight ASP LBW DNAMETHYLATION 
New discoveries generate new questions about RNA-directed DNA methylation in Arabidopsis
《National Science Review》2017年第1期10-15,共6页Huiming Zhang Jian-Kang Zhu 
supported by the Chinese Academy of Sciences(CAS Hundred Talents Program);supported by the CAS and by the US National Institutes of Health(R01GM070795)
Plants can establish de novo DNA methylation via the RNA-directed DNA methylation(RdDM)pathway,which involves a complex array of proteins as well as small interfering RNAs(siRNAs)and scafold RNAs.In the canonicalRd DM...
关键词：DCL RNA DNAMETHYLATION AGO 
Epigenetic therapy of cancer stem and progenitor cells by targeting DNA methylation machineries被引量：9
《World Journal of Stem Cells》2015年第1期137-148,共12页Patompon Wongtrakoongate 
Recent advances in stem cell biology have shed light on how normal stem and progenitor cells can evolve to acquire malignant characteristics during tumorigenesis. The cancer counterparts of normal stem and progenitor ...
关键词：CANCER STEM and PROGENITOR cells DNAMETHYLATION EPIGENETIC therapy Aza-cytidine Azadeoxycytidine 
Epigenetic mechanisms in cardiac development and disease被引量：14
《Acta Biochimica et Biophysica Sinica》2012年第1期92-102,共11页Marcus Vallaster Caroline Dacwag Vallaster Sean M.Wu 
During mammalian development, cardiac specification and ultimately lineage commitment to a specific cardiac cell type is accomplished by the action of specific tran- scription factors （TFs） and their meticulous cont...
关键词：EPIGENETICS histone modifications DNAMETHYLATION congenital heart disease 
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