National Natural Science Foundation(U1604108);Key Science and Technology Program of Henan Province(152102310112; 162102310121);National Training Program of Innovation for Undergraduates(201710472009)
OBJECTIVE Extracellular amyloid-β(Aβ) plaques are one of the major pathological hallmarks of Alzheimer disease(AD). Therefore, decreasing Aβ levels is one strategyfor preventing the etiology of AD. Aβ peptides are...
Supported by the National Natural Science Foundation of China(No.81173383 and No.81573819);Beijing Municipal Science and Technology Plan "Ten Disease and Ten Medicine"(No.Z141100002214003)
Objective To observe the effects of Huannao Yicong Formula (还脑益聪方, HYF) on learning and memory and it’s regulating effect on γ-secretase related anterior pharynx defective 1 (APH-1), presenilin enhancer-2 (PEN-...
Alzheimer's disease is the ultimate .scourge of mankind that haunts the ageing population and increas- ingly becomes the major health and social problem faced by our society. Alzheimer's disease (AD), described b...
the Natural Science Foundation of Bei-jing, No. 7073088
BACKGROUND: Chronic cerebral hypoxia and ischemia have been shown to be related to occurrence of sporadic Alzheimer's disease, and β- and y-secretase play an important role in the generation of β-amyloid protein. ...