National Natural Science Foundation of China(81873761,81571178,81371399);National 13th Five-Year Plan Major Science and Technology Project(2018ZX10302104).
The spread of AIDS and increasing use of immunosuppressive therapy have led to a yearly increase in the incidence of immunodeficiency-associated pneumonia(IAP).The pathogenic spectrum,clinical features,and prognosis o...
Supported by Sanitation Research Project of Kunming Municipal Health Commission,No.2020-06-01-119.
BACKGROUND Pulmonary alveolar proteinosis(PAP)and X-linked agammaglobulinemia(XLA)are rare diseases in children.Many theories infer that immunodeficiency can induce PAP,but these reports are almost all review articles...
In a recent Cell article,McAuley,Kohn et al.showcased proof-of-principle of a promising gene therapy(GT)approach to correct the underlying genetic defect responsible for CD3δ-deficient severe combined immunodeficienc...
Epstein-Barr virus (EBV) mucocutaneous ulceration is a rare complication of immunosuppression that results in painful ulceration of the tongue or gingiva, and less commonly, refractory ulceration of the gastrointestin...
This study was supported by a grant from the Beijing Hospitals Authority Youth Programme(No.QML20181805)。
To the Editor:Kaposi’s sarcoma(KS),a low-grade vascular tumor,is one of the most common neoplasms reported in patients with acquired immunodeficiency syndrome(AIDS).Based on epidemiological and clinical characteristi...
Supported by Chinese National Special Research Program for Important Infectious Diseases,No.2017ZX10202102-002-002;National Science and Technology Major Project,No.2018ZX10715-014-004
BACKGROUND Kaposi’s sarcoma(KS)is one of the most common cancers in human immunodeficiency virus(HIV)-positive patients and leads to a high prevalence of morbidity and mortality.It usually appears as cutaneous or muc...
Backgrounds Common variable immunodeficiency(CVID),the most prevalent form of primary immunodeficiency(PID),is characterized by hypogammaglobulinemia and recurrent infections.Understanding protein-protein interaction(...