MADECASSOSIDE

作品数：5被引量：16H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Plant Communications》《Advances in Alzheimer's Disease》《Asian Agricultural Research》更多>>
相关基金：国家自然科学基金更多>>
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Madecassoside impedes invasion of rheumatoid fibroblast-like synoviocyte from adjuvant arthritis rats via inhibition of NF-κB-mediated matrix metalloproteinase-13 expression被引量：10
《Chinese Journal of Natural Medicines》2018年第5期330-338,共9页YU Wei-Guang SHEN Yong WU Jian-Zhong GAO Yan-Bing ZHANG Li-Xing 
Fibroblast-like synoviocytes(FLS) play a pivotal role in Rheumatoid arthritis(RA) pathogenesis through aggressive migration and invasion. Madecassoside(Madec), a triterpenoid saponin present in Centella asiatica herbs...
关键词：RHEUMATOID ARTHRITIS Fibroblast-like SYNOVIOCYTES MADECASSOSIDE Adjuvant-induced ARTHRITIS Matrix metalloproteinase-13 INVASION 
A LC-ESI-MS method for the simultaneous determination of madecassoside and its metabolite madecassic acid in rat plasma: comparison pharmacokinetics in normal and collagen-induced arthritic rats被引量：5
《Chinese Journal of Natural Medicines》2014年第12期943-951,共9页WANG Ting LENG Dan-Dan GAO Fei-Fei JIANG Chun-Jie XIA Yu-Feng DAI Yue 
financially supported by the National Natural Science Foundation of China(No.81374038,81173631);the Jiangsu Overseas Research&Training Program for University Prominent Young&Middle-aged Teachers and Presidents;sponsored by Qing Lan Project,College Students Innovation Project for the R&D of Novel Drugs(No.J1030830);partially funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
To develop a simple and highly sensitive high performance liquid chromatography with electrospray ionization mass spectrometric(LC-ESI-MS) method for the simultaneous determination of madecassoside and its major metab...
关键词：MADECASSOSIDE Madecassic acid LC-ESI-MS PHARMACOKINETICS Collagen-induced arthritis 
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