National Natural Science Foundation of China (Nos. 21172120 and 21472093);Tianjin Municipal Science and Technology Commission (No. 14JCYBJC20600) for financial support
A mild and efficient n Bu4 NBr-mediated oxidative cycloaromatization to prepareβ-carbolines from readily available tryptophans and aldehydes is described.The reaction is practical and allows the synthesis ofβ-carbol...
Project supported by the National Natural Science Foundation of China ; the State Educational Committee
Carboline I was reduced with lithium aluminum hydride to provide 4 (the related ratio for 4S.R and 4S,S is I 2) which reacts with methyl vinyl ketone to form 5 (the related ratio for 5S,R and 5S.S is 1.2: I). Under th...
Project supported by National Natural Science Foundation of China(No.2870083)
A new method to tetrahydro-β-carbolines(βCs) from tryptamine is described and the aromatization of THβCs to βCs by manganese dioxide is reported for the first time in this type of compounds.
Project supported by National Natural Science Foundation of China(No.2870083)
By the condensation of tryptamine with appropriate substituted benzalde- hyde followed by Pictet-Spengler reaction,a series of 1-aryl-tetrahydro-β-carbo- lines(THβCs)were obtained.After dehydrogenation using sulfur,...