OBJECTIVE Senna and rhubarb are classified as stimulative laxatives,and known to have similar effective constituents,the anthraquinones.Being protected by theβ-glucoside bond,the anthraquinones can reach the intestin...
the National Natural Science Foundation of China(81673562 and 81973467);the Fundamental Research Funds for the Central Universities of China(2020-JYB-ZDGG-033).
Objective:To determine the mechanism of the laxative effect of rhubarb(Rheum tanguticum Maxim.ex Balf.)in rats using a combined bioinformatic and in vivo approach.Methods:Substances derived from rhubarb that are prese...
supported by the Knowledge Innovation Program of Shenzhen(JCYJ20160428181415376 andJCYJ20150529153646078)
Chemical examination of an EtOAc extract of cultured Aspergillus versicolor fungus from deep-sea sediments resulted in the isolation of four xanthones, eight anthraquinones and five alkaloids, including a new xanthone...
financial support from the Major Scientific and Technological Special Project for"Significant New Drugs Creation"(No.2014ZX09304307)
Objective: Anthraquinone(AQ), a major bioactive component of the traditional Chinese medicine He ShouW u, has widespread applications in industry and medicine. The objective of the current study is to explore the diff...
National Natural Science Foundation of China(No.81274179)
Objective To develop a simple, sensitive, and precise method for simultaneous determination of 10 anthraquinones in Rhubarb. Methods HPLC-Q-HR/MS was employed for simultaneous quantification of free anthraquinones(al...
Objective:To investigate the potential of bidirectional solid fermentation of rhubarb (Rheum palmatum L.) for reducing its toxicity and enhancing its medicinal efficacy.Methods:The fungus Trametes robiniophila Murr.wa...
Special Fund of the National Bureau of TCM(No.201407003)
Objective To establish a new method with near-infrared(NIR) spectroscopy to determine the total content of emodin, chrysophanol, rhein, aloeemodin, and physcion. NIR was used in this study to provide rapid and nonde...
National Natural Sciences Foundation of Chin(NS FC;Grant Nos.81222051 and 81473106);National Key Technology R&D Program"New Drug Innovation"of China(Gran No s.2012ZX09301002-002-002 and 2012ZX09304-005)
A phytochemical investigation on the stems and rhizomes of Sinomenium acutum led to the isolation of 19 compounds, including three phenanthrenes, six anthraquinones, and ten phenolic derivatives. The structures of the...
The Research Fund of Chongqing Science&Technology Commission(Grant No.cstc2013jcyj A10040);Research Start-up Fund of Pharmacy School of Chongqing Medical University
The main active components of Rhubarb are anthraquinones(AQs), most of which are glycosides and others are free. The concentrations of AQs derivatives(rhein, aloe-emodin, emodin, chrysophanol and physcion) in plas...
supported by the traditional Chinese Medicine Industry Special Scientific Research (No.201307002);the National New Drug Innovation Major Project of China (No.2012ZX09304005002);A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
Objective: To establish a rapid, accurate and reliable analytical method for the simultaneous determination of four major anthraquinones in Polygoni Multiflori Radix(PMR) using single reference standard.Methods: The f...