The relationship between genetic alterations at chromosomal band 11p13 and the WAGR(Wilms'tumor,aniridia,genitourinary anomalies,and mental retardation)syndrome is not clearly understood.To aid our understanding of th...
funded by grants from the National Natural Science Foundation of China(No:82003523);the Natural Science Foundation of Guangdong Province(No:2021A1515010860);the Science and Technology Project of Guangzhou(No:202102010170).
To the Editor:Wilms tumor,or nephroblastoma,is the most frequently diagnosed pediatric kidney cancer,accounting for>90%of all renal tumors in children 1–7 years old,and the disease may be related to genetic factors.^...
Background: Wilms’ tumor (WT), the most common malignant neoplasm of the urinary tract of children [1], accounts for 5.9% of childhood cancers and affects one in every 10,000 children worldwide before the age of 15 y...
supported by the grant received from Tehran University of Medical Sciences(TUMS-38292)。
Severely immunocompromised NOD.Cg-PrkdcIl2rg(NOG)mice are among the ideal animal recipients for generation of human cancer models.Transplantation of human solid tumors having abundant tumor-i nfiltrating lymphocytes(T...