NEOTENY

作品数：4被引量：16H指数：1
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Brain developmental and cortical connectivity changes in transgenic monkeys carrying the human-specific duplicated gene SRGAP2C被引量：1
《National Science Review》2023年第11期40-55,共16页Xiaoyu Meng Qiang Lin Xuerui Zeng Jin Jiang Min Li Xin Luo Kaimin Chen Haixu Wu Yan Hu Cirong Liu Bing Su 
supported by National Natural Science Foundation of China(U2002207,32000406 and 32170628);Yunnan Province Science and Technology Department(2020-182);Youth Innovation Promotion Association of Chinese Academy of Sciences(to X.L.).
Human-specific duplicated genes contributed to phenotypic innovations during the origin of our own species, such as an enlarged brain and highly developed cognitive abilities. While prior studies on transgenic mice ca...
关键词：SRGAP2C transgenic monkey brain evolution brain development NEUROGENESIS NEOTENY 
Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development被引量：15
《National Science Review》2019年第3期480-493,共14页Lei Shi Xin Luo Jin Jiang Yongchang chen Cirong Liu Ting Hu Min Li Qiang Lin Yanjiao Li Jun Huang Hong Wang Yuyu Niu Yundi Shi Martin Styner Jianhong Wang Yi Lu Xuejin Sun Hualin Yu Weizhi Ji Bing Su 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB13000000to B.S.);the National Natural Science Foundation of China(31730088 and 31621062 to B.S.);the Youth Innovation Promotion Association of CAS(to L.S.)
Brain size and cognitive skills are the most dramatically changed traits in humans during evolution and yet the genetic mechanisms underlying these human-specific changes remain elusive.Here,we successfully generated ...
关键词：HUMAN evolution brain development MCPH1 TRANSGENIC MONKEY NEOTENY COGNITION 
On the identification of paedomorphic and overwintering larval newts based on cloacal shape： review and guidelines
《Current Zoology》2017年第2期165-173,共9页Mathieu DENOEL 
Paedomorphosis is an alternative process to metamorphosis in which adults retain larval traits at the adult stage. It is frequent in newts and salamanders, where larvae reach sexual maturity with- out losing their gil...
关键词：amphibians cloacal morphology facultative paedomorphosis NEOTENY REVIEW secondary sexual traits sexual di-morphism sexual maturity. 
Prefrontal cortical dopamine from an evolutionary perspective被引量：1
《Neuroscience Bulletin》2015年第2期164-174,共11页Young-A Lee Yukiori Goto 
supported by Kyoto University;the Ito Chubei Foundation;the Ichiro Kanehara Foundation;the Institute of Life & Seizon, Japan
In this article, we propose the hypothesis that the prefrontal cortex （PFC） acquired neotenic development as a consequence of mesocortical dopamine （DA） innervation, which in turn drove evolution of the PFC into b...
关键词：NEURODEVELOPMENT NEOTENY psychiatric disorder stress animal model synaptic plasticity environmental adaptation 
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