Depression is a common mental disorder and one of the leading causes of disability around the world.Monoaminergic antidepressants often take weeks to months to work and are not effective for all patients.This has led ...
supported by the PRIN 2015(Pr.2015R9ASHT);PON AIM(PON RICERCA E INNOVAZIONE 2014-2020,-AZIONE I.2.D.D.N.407 DEL 27 FEBBRAIO 2018-“ATTRACTION AND INTERNATIONAL MOBILITY”);supported by Autonomous Region of Sardinia(RAS-FSC 2018,Codice intervento:RC_CRP_034;CUP RASSR03071);supported by Fondazione di Sardegna(Progetti Biennali Uni CA,Annualità2017)
Preclinical and clinical studies indicate that synthetic psychoactive substances,in addition to having abuse potential,may elicit toxic effects of varying severity at the peripheral and central levels.Nowadays,toxicit...
Project supported by the Natural Science Foundation of Shanxi Province (No. 2007011025) and Scientific Research Foundation for the Returned Overseas Chinese Scholars of Shanxi Province.
DFT/B3LYP/6-311G+(d,p) basis set including solvent effect was first used to calculate a set of molecular descriptors of 55 phenylalkylamine and 20 tryptamine compounds with hallucinogenic activity. Four quantitativ...
supported by the Natural Science Foundation of Shanxi Province (2007011025)
A Quantitative Structure-activity Relationship(QSAR) model was developed to predict the hallucinogenic activity of phenylalkylamines by Artificial Neural Network(ANN) method.Each compound was represented by the ca...