云南高校图书馆联盟文献共享服务平台- CYPROHEPTADINE

CYPROHEPTADINE: 作品数：13被引量：8H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王立赞论宁王保生朱凡河张庆柱更多>>; 相关机构：济宁医学院山东大学生物化学教研室潍坊医学院更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Chinese Medical Journal》《World Journal of Critical Care Medicine》《Neuroscience Bulletin》更多>>; 相关基金：上海市教育委员会重点学科基金国家自然科学基金更多>>

Serotonin syndrome controversies:A need for consensus: 《World Journal of Critical Care Medicine》2024年第2期150-158,共9页Sanjay Prakash Chetsi S Shah Anurag Prakash; Serotonin syndrome(SS)is a drug-induced clinical syndrome resulting from increased serotonergic activity in the central nervous system.Although more than seven decades have passed since the first description of SS,it ...; 关键词：SEROTONIN Serotonin syndrome Serotonin toxicity Selective serotonin reuptake inhibitors Antidepressants CYPROHEPTADINE

Chronic serotonin syndrome:A retrospective study被引量：2: 《World Journal of Psychiatry》2021年第4期124-132,共9页Sanjay Prakash Chaturbhuj Rathore Kaushik Rana Diptangshu Roychowdhury Deepali Lodha; BACKGROUND Serotonin syndrome(SS)is an underdiagnosed drug-induced clinical syndrome resulting from the excess intrasynaptic concentration of serotonin.Very limited information is available about chronic SS.AIM To eva...; 关键词：Serotonin syndrome Serotonin toxicity CYPROHEPTADINE Serotonergic agents SEROTONIN CLONUS

Cyproheptadine Regulates Pyramidal Neuron Excitability in Mouse Medial Prefrontal Cortex: 《Neuroscience Bulletin》2018年第5期759-768,共10页Yan-Lin He Kai Wang Qian-Ru Zhao Yan-Ai Mei; supported by the National Natural Science Foundation of China(31370827);the Shanghai Leading Academic Discipline Project [B111]; Cyproheptadine （CPH）, a first-generation anti- histamine, enhances the delayed rectifier outward K＋ current （IK） in mouse cortical neurons through a sigma-1 receptor-mediated protein kinase A pathway. In this stu...; 关键词：CYPROHEPTADINE Neuronal excitability Te-traethylammonium-sensitive Ik cortical neurons Sigma-1 receptor

Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways被引量：1: 《Acta Pharmacologica Sinica》2003年第10期958-964,1060,共8页Sheikh Arshad SAEED Huma RASHEED Anwar-ul-Hassan GILANI; Project supported by the research funds from the Aga Khan University, Karachi.; AIM: To examine the signalling mechanisms involved in the synergistic interaction of 5-hydroxytryptamine (5-HT) and arachidonic acid (AA) in human platelet aggregation. METHODS: Blood was obtained from healthy human s...; 关键词：SEROTONIN arachidonic acids platelet aggregation cyclooxygenase inhibitors METHYSERGIDE CYPROHEPTADINE thromboxane A_2 phospholipase C CALCIUM drug synergism

Anti-endotoxic shock effects of cyproheptadine in rats: 《Chinese Medical Journal》2002年第3期443-445,共3页王立赞胡修周王保生朱凡河论宁张庆柱; OBJECTIVE: To investigate the antagonistic effect and mechanism of the effect of cyproheptadine (Cyp) on endotoxic shock in rats. METHODS: Endotoxic shock was produced in rats by i.v. injection of lipopolysaccharides ...; 关键词：Animals CYPROHEPTADINE Histamine H1 Antagonists MALONDIALDEHYDE RATS Rats Wistar Research Support Non-U.S. Gov't Shock Septic Superoxide Dismutase Tumor Necrosis Factor-alpha

Verapamil, cyproheptadine, and anisodamine antagonized [Ca2+]_i elevation induced by TNFa in a single endothelial cell: 《Acta Pharmacologica Sinica》2001年第10期918-922,共5页王立赞张庆柱胡修周论宁朱凡河; Project supported by Shandong Commission of Science and Technology, No 970116; AIM: To study the effect of tumor necrosis factor alpha (TNFa ) on intracellular free Ca2+ concentration ([Ca2+ ]i) and the effects of verapamil (Ver), cyproheptadine (Cyp), and anisodamine (Ani) on TNFa-induced [Ca2+...; 关键词：tumor necrosis factor calcium ENDOTHELIUM VERAPAMIL CYPROHEPTADINE ANISODAMINE cultured cells confocal microscopy

Effects of dexamethasone, cyproheptadine, anisodamine, and dinoprostone on TNF_α production in endotoxic shock被引量：3: 《中国药理学报》1999年第2期171-174,共4页王立赞刘玉琴崔运河朱凡河王保生论宁; 目的：研究地塞米松（Ｄｅｘ）、噻庚啶（Ｃｙｐ）、山莨菪碱（Ａｎｉ）和地诺前列酮（Ｄｉｎ）对脂多糖（ＬＰＳ）诱导的肿瘤坏死因子（ＴＮＦα）基因表达的影响和抑制ＴＮＦα产生的抗休克作用．方法：Ｗｉｓｔａｒ大鼠静脉注射ＬＰ...; 关键词：内毒素休克 TNFα 地塞米松噻庚啶山莨菪碱

Inhibitory effects of cyproheptadine on pituitary-thyroid axis and pancreatic β cells in rats被引量：1: 《中国药理学报》1998年第6期554-556,共3页康白李广宙戴功黄岩; 目的：研究赛庚啶（Ｃｙｐ）对大鼠垂体甲状腺轴和胰岛β细胞内分泌功能的影响．方法：用放射免疫测定法及生化分析法观察赛庚啶对大鼠垂体甲状腺轴和胰岛β细胞内分泌功能的影响．结果：Ｃｙｐ２３ｍｇ·ｋｇ－１，ｉｇ１０ｄ，...; 关键词：赛庚啶垂体腺甲状腺胰岛电镜检抑制作用

THERAPEUTIC EFFECT OF CYPROHEPTADINE ON TRAUMATIC BRAIN EDEMA IN RATS: 《Journal of Pharmaceutical Analysis》1996年第2期146-150,共5页吕键杨庆余王美纳梁健康爱群; Acute traumatic brain edema models were established in SD rats by dropping weight methods.We observed the therapeutic effect of Cyproheptadine(Cyp)on traumatic brain edema.It was shown that Cyp could obviously reduce ...; 关键词：CYPROHEPTADINE traumsatic brain edema lipid peroxide

EFFECTS OF CYPROHEPTADINE ON PLASMA SUPEROXIDE DISMUTASE ACTIVITY AND MALONDIALDEHYDE CONTENT IN RABBITS WITH HEMORRHAGIC SHOCK被引量：1: 《Chinese Medical Journal》1994年第5期5-7,共3页张庆柱张春芬王清李建美凌秀珍; Profound hemorrhagic shock was produced in thirty rabbits by exsanguination via the carotid artery until blood pressure (BP) reached 5.3 kPa (40 mmHg) and was sustained for a period of 90 minutes. The rabbits were equ...; 关键词：SOD EFFECTS OF CYPROHEPTADINE ON PLASMA SUPEROXIDE DISMUTASE ACTIVITY AND MALONDIALDEHYDE CONTENT IN RABBITS WITH HEMORRHAGIC SHOCK MDA

CYPROHEPTADINE