ARECOLINE

作品数：15被引量：40H指数：4
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相关领域：医药卫生更多>>
相关作者：陈盛霞杨小明姜旭淦张蓉仙李龙根更多>>
相关机构：镇江市疾病预防控制中心江苏大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Animal Nutrition》《Chinese Medical Journal》《中国药理通讯》更多>>
相关基金：国家自然科学基金江苏省社会发展科技计划中国博士后科学基金国家高技术研究发展计划更多>>
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Arecoline,a main alkaloid in Areca catechu,induces biological changes in human papillomavirus 16-positive cervical cancer cells via upregulation of viral oncogenes and cellular transcriptional factors
《Asian Pacific Journal of Tropical Biomedicine》2025年第3期119-128,I0016-I0018,共13页Jureeporn Chuerduangphui Chaleampol Loymunkong Tipaya Ekalaksananan Chamsai Pientong 
Objective:To investigate the effects of arecoline on HPV-positive cervical cells and unveil its underlying mechanism in cervical carcinogenesis.Methods:The cytotoxicity of arecoline was determined and the effect of su...
关键词：ARECOLINE Human papillomavirus ONCOGENES Cervical cancer c-Fos 
An emerging role of arecoline on growth performance,intestinal digestion and absorption capacities and intestinal structural integrity of adult grass carp(Ctenopharyngodon idella)被引量：2
《Animal Nutrition》2023年第4期173-186,共14页Na Yao Lin Feng Weidan Jiang Pei Wu Hongmei Ren Hequn Shi Ling Tang Shuwei Li Caimei Wu Hua Li Yang Liu Xiaoqiu Zhou 
This research was financially supported by the National Key R&D Program of China(2019YFD0900200,2018YFD0900400);National Natural Science Foundation of China for Outstanding Youth Science Foundation(31922086);supported by the earmarked fund for CARS(CARS-45).
Arecoline is an alkaloid with important pharmacological effects in the plant areca nut,which has been demonstrated to be an agonist of muscarinic receptors(M receptor).This study explored the influences of dietary are...
关键词：ARECOLINE Ctenopharyngodon idella Digestion capacity Absorption capacity Structural integrity INTESTINE 
Research Progress in Arecoline-induced Oral Submucous Fibrosis
《Food Therapy and Health Care》2019年第3期97-101,共5页Jing-Wen Jiang Xue-Wu Chen Qing-Hua Yao Hui Zhang 
Areca nut is a popular fruit, but is among the most common addictions following tobacco, alcohol and caffeine globally. Areca nut chewing is the major risk factor for OSF, which is a chronic, occult, and premalignant ...
关键词：ARECOLINE OSF ENDOTHELIAL cells Mechanism TGF-Β EMT 
Development of a mouse model of arecoline-induced oral mucosal fibrosis被引量：7
《Asian Pacific Journal of Tropical Medicine》2017年第12期1177-1184,共8页Qi-Tao Wen Tao Wang Da-Hai Yu Zheng-Rui Wang Ying Sun Cui-Wei Liang 
supported by grants from the National Natural Science Foundation of China(Grant No.81460105);the National Natural Science Foundation of China(Grant No.81360407);the National Natural Science Foundation of Hainan Province(Grant No.2058321);Foundation of Health Department of Hainan Province(Grant No.14A210189)
Objective: To develop a BALB/c mouse model of oral submucous fibrosis(OSF)induced by arecoline and to exhibit an accumulation of collagen and angiogenesis changes.Methods: BALB/c mice were randomly assigned to either ...
关键词：Oral submucous fibrosis Mouse model ARECOLINE ANGIOGENESIS COLLAGEN 
Analysis of arecoline in Semen Arecae decoction pieces by microchip capillary electrophoresis with contactless conductivity detection被引量：2
《Journal of Pharmaceutical Analysis》2012年第5期356-360,共5页Zi-You Cai Yong-Chong Li Li-Hua Li Zuan-Guang Chen 
support from the National Natural Science Foundation of China (Nos. 20727006,21075139);Guangdong Provincial Science and Technology Project (2008A030102009);the Medical Scientific Research Foundation of Guangdong Province(A2012155)
A new method for the determination of arecoline in Semen Arecae decoction pieces by microchip capillary electrophoresis with contactless conductivity detection （MCE-CCD） was proposed. The effects of various electrop...
关键词：Microchip capillary electrophoresis Contactless conductivity detection ARECOLINE Semen Arecae 
Arecoline improves vascular endothelial function in high fructose-fed rats via increasing cystathionine-γ-lyase expression and activating KATP channels被引量：4
《Acta Pharmacologica Sinica》2012年第8期1023-1029,共7页Hong-yan LING Guang WANG Wei ZHANG Xing LI Shou-hong ZHOU Bi HU 
This work was supported by the National Natural Science Foundation of China （No 81000328）, the fifty-first batch of China Postdoctoral Science Foundation （No 2012M511384）, and the Fund of the Research Project of Department of Science and Technology of Hunan Province （No 2007TP4018）.
Aim： To investigate the effect of arecoline, a major component of betel nut, on vascular endothelial function in high fructose-fed rats and the potential mechanisms underlying the effect. Methods： Male Wistar rats w...
关键词：ARECOLINE betel-quid chewing propargylglycine glibenclamide high fructose-fed rat endothelium-dependent vasorelaxation cystathionine-y-lyase KATP channel diabetes mellitus vascular endothelial dysfunction 
Frequency- and state-dependent blockade of human ether-a-go-go-related gene K^＋ channel by arecoline hydrobromide
《Chinese Medical Journal》2012年第6期1068-1075,共8页ZHAO Xu-yan LIU Yu-qi FU Yi-cheng XU Bin GAO Jin-liao ZHENG Xiao-qin LIN Min CHEN Mei-yan LI Yang 
This study was supported by the grants from the National Natural Science Foundation of China （No. 81170177 and No. 30770901 ）.Acknowledgment： We would like to thank Prof. Priori, University of Pavia in Italy for generously providing the hERG plasmid.
Background The rapidly activating delayed rectifier potassium current （/Kr）, whose pore-forming alpha subunit is encoded by the human ether-a-go-go-related gene （hERG）, is a key contributor to the third phase of a...
关键词：arecoline hydrobromide hERG current anti-arrhythmic agent frequency-dependent manner state-dependent manner 
Effects of Arecoline Hydrobromide on Taeniasis and Cysticercosis in Domestic Animals
《Animal Husbandry and Feed Science》2010年第6期30-32,35,共4页ZHOU Xu-zheng ZHANG Ji-yu LI Jianoyong LI Jin-shan WEI Xiao-juan NIU Jian-rong LI Bing 
supported by the Technology Development and Research Projects of Ministry of Science and Scientific Research Institutes(NCSTE-2006-JKZX-293);Science and Technology Major Projects in Gansu Province(2009GS02443);the National Science and Technology Support Program of China(2008BADB4B05)
Taeniasis and cysticercosis in domestic animals belong to zoonosis and seriously threaten the public health security. Especially the cysticercosis and echinococcosis caused by the tapeworm eggs have great harms to bod...
关键词：TAENIASIS CYSTICERCOSIS Arecoline hydrobromide 
Security of a Novel Antitapeworm Drug:Arecoline Hydrobromide
《Animal Husbandry and Feed Science》2010年第2期26-28,31,共4页ZHOU Xu-zheng ZHANG Ji-yu LI Jin-shan LI Jian-yong WEI Xiao-juan NIU Jian-rong LI Bing 
supported by Technology Development and Research Projects of Ministry of Science and Scientific Research Institutes(NCSTE-2006-JKZX-293);Science and Technology Major Projects in Gansu Province(2009GS02443);National Science and Technology Support Program of China (2008BADB4B05)
[Objective] To make an objective evaluation about security of a new veterinary drug-arecoline hydrobromide according to the research results and papers in recent years and supply science basis for clinical usage. [ Me...
关键词：Arecoline hydrobromide Acute toxicity ＂Three-induced＂ effects Reproductive toxicity 
银杏外种皮对钉螺的杀灭机理被引量：13
《动物学报》2007年第1期190-194,共5页陈盛霞 吴亮 杨小明 姜旭淦 李龙根 张蓉仙 夏磊 邵世和 
江苏省社会发展基金资助项目(BS2005042)~~
To study the toxicity of extracts of Ginkgo biloba sarcotesta to Oncomelania hupensis,snails were exposed to 40% and 80% of 24 h LC 50 of the extract of Ginkgo bilba for 24 h,choline esterase(ChE),alanine aminotransfe...
关键词：Oncomelania hupensis Enzyme kinetic assay Sarcotesta of Ginkgo biloba ARECOLINE NICLOSAMIDE 
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