云南高校图书馆联盟文献共享服务平台- ONCOGENES

ONCOGENES: 作品数：91被引量：502H指数：14; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：黄志刚杨玉成洪苏玲尚涛董潇更多>>; 相关机构：首都医科大学重庆医科大学附属第一医院中国医科大学附属第一医院中国医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划重庆市卫生局科研项目更多>>

Arecoline,a main alkaloid in Areca catechu,induces biological changes in human papillomavirus 16-positive cervical cancer cells via upregulation of viral oncogenes and cellular transcriptional factors: 《Asian Pacific Journal of Tropical Biomedicine》2025年第3期119-128,I0016-I0018,共13页Jureeporn Chuerduangphui Chaleampol Loymunkong Tipaya Ekalaksananan Chamsai Pientong; Objective:To investigate the effects of arecoline on HPV-positive cervical cells and unveil its underlying mechanism in cervical carcinogenesis.Methods:The cytotoxicity of arecoline was determined and the effect of su...; 关键词：ARECOLINE Human papillomavirus ONCOGENES Cervical cancer c-Fos

MicroRNAs modulation in lung cancer: exploring dual mechanisms and clinical prospects: 《BIOCELL》2024年第3期403-413,共11页SHAHID HUSSAIN HABIB BOKHARI XINGXING FAN SHAUKAT IQBAL MALIK SUNDAS IJAZ MUHAMMAD ADNAN SHEREEN AIMAN FATIMA; The global incidence of lung cancer is marked by a considerably elevated mortality rate.MicroRNAs(miRNAs)exert pivotal inﬂuence in the intricate orchestration of gene regulation,and their dysregulation can precipitate...; 关键词：MIRNAS ONCOGENES Tumor suppressive genes Lung cancer therapy

Emerging role of MYB transcription factors in cancer drug resistance: 《Cancer Drug Resistance》2024年第1期797-832,共36页Bernhard Biersack Michael Höpfner; Decades ago,the viral myeloblastosis oncogene v-myb was identified as a gene responsible for the development of avian leukemia.However,the relevance of MYB proteins for human cancer diseases,in particular for solid tu...; 关键词：Anticancer drugs MYB transcription factors ONCOGENES drug resistance cancer resistance mechanisms MYB-targeting drugs

Critical involvement of circular RNAs in virus-associated cancers被引量：2: 《Genes & Diseases》2023年第6期2296-2305,共10页Arghavan Zebardast Tayebeh Latifi Moein shirzad Golnaz Goodarzi Saeed Ebrahimi Fana Sadra Samavarchi Tehrani Yousef Yahyapour; Virus-related cancer is cancer where viral infection leads to the malignant transformation of the host's infected cells. Seven viruses (e.g., human papillomavirus (HPV), Epstein–Barr virus (EBV), Kaposi's sarcoma her...; 关键词：Cancer Circular RNA NEOPLASMS ONCOGENES Viruses

A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m^(6)A-dependent activation of multiple oncogenes被引量：3: 《Science China(Life Sciences)》2023年第9期2138-2151,共14页Yingxiu Luo Mengjia He Jie Yang Feifei Zhang Jie Chen Xuyang Wen Jiayan Fan Xianqun Fan Peiwei Chai Renbing Jia; supported by the National Natural Science Foundation of China (81570884, 81872339, and 82272642);Shanghai Municipal Science and Technology Major Project (17JC1420100and 19JC1410202);Shanghai Science and Technology Development Funds (17DZ2260100 and 19QA1405100);Ninth People’s Hospital Excellent Youth Fund Program (JYYQ003)。; Retinoblastoma, the most prevalent primary intraocular tumor in children, leads to vision impairment, disability and even death.In addition to RB1 inactivation, MYCN activation has been documented as another common on...; 关键词：MYCN YTHDF1 m^(6)A CDK5R1 RETINOBLASTOMA

Molecular genetics of early-onset colorectal cancer被引量：1: 《World Journal of Biological Chemistry》2023年第2期13-27,共15页Olivia Marx Marc Mankarious Gregory Yochum; Early-onset colorectal cancer(EOCRC)has been rising in global prevalence and incidence over the past several decades.Environmental influences,including generational lifestyle changes and rising obesity,contribute to t...; 关键词：Early-onset colorectal cancer Later-onset colorectal cancer Mutations ONCOGENES Molecular characteristics TRANSCRIPTOMICS

Curse and blessing:upregulation of oncogenes upon treatment with hypomethylating agents in myelodysplastic syndrome: 《Signal Transduction and Targeted Therapy》2022年第9期3150-3151,共2页Juliane Grimm Mascha Binder; In a recently published study in The New England Journal of Medicine,Liu and colleagues were able to demonstrate that-apart from the antileukemic effects previously reported for hypomethylating agents(HMAs)-treatment ...; 关键词：DRUGS myelo TREATMENT

Paradoxical effects of DNA tumor virus oncogenes on epithelium-derived tumor cell fate during tumor progression and chemotherapy response被引量：1: 《Signal Transduction and Targeted Therapy》2021年第12期3767-3782,共16页Jiang He Liyu Liu Feiyu Tang You Zhou Huan Liu Can Lu Deyun Feng Hong Zhu Yitao Mao Zhi Li Lu Zhang Yuemei Duan Zhi Xiao Musheng Zeng Liang Weng Lun-Quan Sun; This work was funded by the following grants and associations:National Natural Science Foundations of China(81530084 and 81702721);Hunan province natural science funds for Yong scholars(2018JJ3816).; Epstein-Barr virus(EBV)and human papillomavirus(HPV)infection is the risk factors for nasopharyngeal carcinoma and cervical carcinoma,respectively.However,clinical analyses demonstrate that EBV or HPV is associated wi...; 关键词：CHEMOTHERAPY EPITHELIUM CERVICAL

Novel oncogenes and tumor suppressor genes in hepatocellular carcinoma被引量：3: 《Liver Research》2021年第4期195-203,共9页Fang Wang Peter Breslin S J Wei Qiu; Hepatocellular carcinoma(HCC)is a very deadly disease.HCC initiation and progression involve multiple genetic events,including the activation of proto-oncogenes and disruption of the function of specific tumor suppres...; 关键词：Hepatocellular carcinoma(HCC) ONCOGENE Tumor suppressor Activation LOSS-OF-FUNCTION

Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy被引量：6: 《Acta Pharmaceutica Sinica B》2021年第9期2738-2748,共11页Kailin Li Jieqiong You Qian Wu Wen Meng Qiaojun He Bo Yang Chengliang Zhu Ji Cao; supported by grants from the National Natural Science Foundation of China(No.81872885 to Ji Cao);the Zhejiang Provincial Natural Science Foundation of China(No.LY15H160009 to Wen Meng); Synthetic lethality is a proven effective antitumor strategy that has attracted great attention.Large-scale screening has revealed many synthetic lethal genetic phenotypes,and relevant smallmolecule drugs have also be...; 关键词：Synthetic lethality Cyclin-dependent kinase Antitumor therapy ONCOGENES MYC P53 RAS PARP

ONCOGENES