funded by a grant from the Misophonia Research Fund;so Quiet Foundation。
Despite the increasing investigation into misophonia,its classification remains debated due to symptom overlap with audiological and psychological conditions,as well as methodological limitations in existing studies.I...
M.A.was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences,National Institutes of Health,through Grant TL1TR001415.
In a recent study published in Science Advances,Liu et al.demonstrated that heterozygous deletion of connexin 26(Cx26)in mice is not harmless as they lead to hyperacusis-like hearing oversensitivity.The authors also f...
Objective:To determine the circadian influence on sound sensitivity produced by temporal hearing deprivation in healthy normal human subjects.Design:Participants underwent bilateral earplugging before completion of an...
supported by the National Institute for Health ResearchManchester Biomedical Research Centre.
Introduction:Auditory symptoms in individuals with Autistic Spectrum Disorder(ASD)are well described within the neurodevelopmental literature,yet there is minimal mention of ASD in Otolaryngology literature.This is su...
Objective:To assess hyperacusis after stapedotomy and its possible influencing factors.Study design:Prospective,interventional,and longitudinal study.Setting:A tertiary referral center.Patients:Fifty consecutive patie...
Introduction:Hypersensitivity to sound and tinnitus are often co-morbid and can influence emotional well-being,hearing,sleep,concentration,cause anxiety,and interfere with speech perception in noise.Purpose:A clear me...
Background: This study aimed to compare the neurophysiological responses to sound in adults with hypersensitivity compared to adults without hypersensitivity, and correlate the daily-life experiences to the neurophysi...
There is growing evidence suggests that noise-induced cochlear damage may lead to hyperexcitability in the central auditory system(CAS)which may give rise to tinnitus.However,the correlation between the onset of the n...
The acoustic startle response has been used to evaluate tinnitus and hyperacusis in animal models. Gap induced prepulse in- hibition of the acoustic startle reflex (gap-PPI) is affected by tinnitus and loudness chan...
Fragile X syndrome is the most common form of inherited mental retardation affecting up to 1 in 4000 individuals. The syn- drome is induced by a mutation in the FMR1 gene, causing a deficiency in its gene by-product F...