supported by the National Natural Science Foundation of China(82330011,U21A20339);the CAMS Innovation Fund for Medical Sciences(CIFMS,2020-I2M-5-003);the National Natural Science Foundation of China(No.82370302,31871175);Natural Science Foundation of Heilongjiang Province of China(No.YQ2019H003);College of Pharmacy,Harbin Medical University Excellent Young Talents Funding(No.2020-YQ-01).
Background:Small ubiquitin-like modifiers(SUMO)ylation is a dynamic and reversible post-translational modification playing pivotal roles in the regulation of cancer,diabetes,heart failure,and neurological diseases.How...
supported by the National Key Research and Development Program of China(2023YFF1105201);the China Dairy Industry Association Dairy Science and Technology Innovation Fund(CDIAKCJJ-MN-2023-001);the National High Level Hospital Clinical Research Funding(bj-2023-72);the 111 project from the Education Ministry of China(B18053).
The inconsistent findings concerning the effects of vitamin D supplementation on cardiometabolic risk factors and the large heterogeneity in the published literature call for further research to identify sources of he...
Epigenetic modifiers are enzymes that catalyze covalent chemical modifications on chromatin and thus play important roles in setting relatively stable states for gene expression and cell identity.It has been widely ob...
financially supported by the National Natural Science Foundation of China(Nos.52073038 and 51873027);the Fundamental Research Funds for the Central Universities(No.DUT22LAB605)。
Toughening the petroleum-based epoxy resin blends with bio-based modifiers without compromising their modulus,mechanical strength,and other properties is still a big challenge in view of the sustainability.In this stu...
Our brain is constantly active.Even at rest,the brain carries out essential functions such as maintenance of resting potentials,subthreshold synaptic activity,and spiking activity related to information processing.Thi...
This review emphasizes the recent advancements and prospects of thin-film kesterite-based photovoltaic(PV)applications using magnesium,iron and nickel.The quest for novel materials employed in solar cells has resulted...
supported by the National Key Research and Development Project(2022YFD1602107);the Key S&T Special Projects of Shaanxi Province,China(2020zdzx03-01-02);the Natural Science Foundation of Shaanxi Province,China(2022JQ-179).
Heat stress,which is caused by global warming,threatens crops yield and quality across the world.As a kind of post-translation modification,SUMOylation involves in plants heat stress response with a rapid and wide pat...
Antibiotics and their metabolic byproducts are found in wastewater and natural water as a result of increased consumption,posing a major threat to humans and other living organisms.One of the most promising methods fo...
financially supported by The Research Council of Norway(Norges Forskningsrådet,Project#301745).
Using periodic measurements from permanent plots in non-thinned and thinned Norway spruce(Picea abies(L.)H.Karst.)stands in Norway,individual-tree growth models were developed to predict annual diameter increment,heig...
supported by the National Natural Science Foundation of China (Nos. 41877228, 41877229 and 42102303);Guangdong Basic and Applied Basic Research Foundation (Nos. 2018B030311066 and 2019A1515010554);China Postdoctoral Science Foundation (No. 2019M663241);Science and Technology Program of Guangzhou, China (No. 201904010136)。
The disintegration of granite residual soil is especially affected by variations in physical and chemical properties. Serious geologic hazards or engineering problems are closely related to the disintegration of grani...