FOTEMUSTINE

作品数：7被引量：3H指数：1
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相关领域：医药卫生更多>>
相关作者：孔祥林于盛海韩小弟徐大江赵继宗更多>>
相关机构：首都医科大学附属北京天坛医院山东省医学科学院更多>>
相关期刊：《Chinese Journal of Cancer Research》《Journal of Cancer Therapy》《Journal of Cancer Metastasis and Treatment》《世界医学杂志》更多>>
相关基金：国家自然科学基金更多>>
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Fotemustine-based therapy in combination with rituximab as a first-line induction chemotherapy followed by WBRT for newly diagnosed primary central nervous system lymphoma: a prospective phase II trial被引量：2
《Cancer Biology & Medicine》2022年第7期1089-1099,共11页Jingjing Wu Fenghua Gao Wenhua Wang Xudong Zhang Meng Dong Lei Zhang Xin Li Ling Li Zhenchang Sun Xinhua Wang Xiaorui Fu Linan Zhu Mengjie Ding Songtao Niu Zhaoming Li Yu Chang Feifei Nan Jiaqian Yan Hui Yu Xiaolong Wu Zhiyuan Zhou Jieming Zhang Mingzhi Zhang 
supported by grants from the National Natural Science Foundation of China(Grant No.81970184),The National Science and Technology Major Project of China(Grant No.2020ZX09201-009);Henan Medical Science and Technology Tacking Program(Joint Project)(Grant No.LHGJ20190021)。
Objective:This study aimed to evaluate the safety,efficacy,and feasibility of the rituximab,fotemustine,pemetrexed,and dexamethasone(R-FPD)regimen followed by whole-brain radiotherapy(WBRT)for patients with primary ce...
关键词：RITUXIMAB primary central nervous system lymphoma PEMETREXED FOTEMUSTINE WBRT 
Complete response with fotemustine and bevacizumab after early progression following radiotherapy and temozolomide treatment in patient with glioblastoma multiforme
《Journal of Cancer Metastasis and Treatment》2015年第1期36-38,共3页Ovidio Fernández Calvo María Eva Pérez López Jesús García Gómez 
Glioblastoma multiforme is the most common type of primary central nervous system tumor and is noted for its short survival and poor response to chemotherapeutic agents.Unfortunately,the relapse rate is very high,and ...
关键词：BEVACIZUMAB brain tumor FOTEMUSTINE 
Complete Remission and Long Term Survival in Recurrent Malignant Glioblastoma Treated with Fotemustine Monotherapy: A Case Report
《Journal of Cancer Therapy》2013年第2期584-587,共4页Carmine Cerullo Carla Fonte Andrea Muto Agnese Vannini Mattia Rediti Sheila Rangan Lorenzo Bordi Bruno Neri 
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor. Conventional therapies are considered palliative and long-term progression-free survival remains low for most GBM patients even after surgical e...
关键词：Fotomustine GLIOBLASTOMA MULTIFORME RECURRENCE Treatment Survival 
A Phase Ⅱ Study of Fotemustine Plus Dacarbazine with Dendritic Cell Vaccines as First-Line Therapy for Chinese Patients with Advanced Acral Lentiginous Melanoma被引量：1
《Chinese Journal of Cancer Research》2009年第1期13-19,共7页Lu Si Zhi-hong Chi Xiang-qing Yuan Chuan-liang Cui Xi-nan Sheng Jun Guo 
Objective： To investigate fotemustine plus dacarbazine （DTIC） with dendritic cell （DC） vaccines on patients with advanced acral lentiginous melanoma （ALM）. Fotemustine is a cytotoxic alkylating agent with a rem...
关键词：FOTEMUSTINE DACARBAZINE Dendritic cell MELANOMA 
恶性胶质瘤术后Fotemustine化疗的疗效和毒性评估
《世界医学杂志》1999年第12期16-19,共4页韩小弟 赵继宗 
４０例手术后确认为恶性胶质瘤患者进行了Ｆｏｔｅｍｕｓｔｉｎｅ化疗，方案为每周一次静脉给药，剂量１００ｍｇ／ｍ＾２，共３周，休息５周后，进行维持期治疗，每３周一次剂量仍为１００ｍｇ／ｍ＾２。定期随访并复查脑ＣＴ／ＭＲＩ...
关键词：胶质瘤 术后化疗 疗效 毒性 FOTEMUSTINE 
抗肿瘤新药FOTEMUSTINE的药理和临床
《国外医学（肿瘤学分册）》1991年第4期233-235,共3页于盛海 孔祥林 徐大江 
Fotemustine是一种新的亚硝脲类抗肿瘤药物。于1989年11月在法国上市。经动物实验和临床研究证实,本品对多种肿瘤有效,尤其是对恶性黑色素瘤疗效显著。本文就近年来的研究情况对其药效学、药代动力学及临床研究进行了综述。
关键词：FOTEMUSTINE 药理 抗癌药 
抗肿瘤药Fotemustine
《国外医药（合成药．生化药．制剂分册）》1991年第1期42-43,共2页曹婉娣 
合成将2-氯乙基异氰酸盐(Ⅰ)与二乙基1-氨乙基磷酸盐(Ⅱ)在氯仿中缩合得二乙基1-[3-(2-氯乙基)脲基乙基磷酸盐(Ⅲ),然后用亚硝酸钠和甲酸处理,即得本品[FR2536075]。
关键词：Fetemustine 抗癌药 抗肿瘤活性 
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