funded by the National Natural Science Foundation of China(Nos.32370023,32370583,31970036,and 31900401);Natural Science Foundation of the Jiangsu Higher Education Institutions of China(20KJB180001 and 20KJA180007);Natural Science Foundation of Jiangsu Province(BK20210920 and BK20231350);Jiangsu Agricultural Science and Technology Innovation Fund(Cx223125);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
Nucleotide second messengers are highly versatile signaling molecules that regulate a variety of key biological processes in bacteria.The best-studied examples are cyclic AMP(cAMP)and bis-(3'-5')-cyclic dimeric guanos...
the National Natural Science Foundation of China(91951204,32200149);the National Key R&D Program of China(2021YFA0909500,2021YFC2301004,2019YFC804104),and the CAS‐TWAS PhD Fellowship for Pramod Bhasme.
Antibiotic resistance or tolerance of pathogens is one of the most serious global public health threats.Bacteria in biofilms show extreme tolerance to almost all antibiotic classes.Thus,use of antibiofilm drugs withou...
supported by the National Natural Science Foundation of China(Nos.21877036 and 32201044);the Key Project of Developmental Biology and Breeding from Hunan Province(No.2022XKQ0205);the Hunan Natural Science Foundation(No.2021JJ40335);the Science and Technology Planning Project of Hunan Province(No.2018TP1017).
The activation of the stimulating factor of the interferon gene(STING)pathway can enhance the immune response within the tumor.Cyclic diguanylate monophosphate(c-di-GMP)is a negatively charged,hydrophilic STING agonis...