funded by the National Natural Science Foundation of China(Nos.32370023,32370583,31970036,and 31900401);Natural Science Foundation of the Jiangsu Higher Education Institutions of China(20KJB180001 and 20KJA180007);Natural Science Foundation of Jiangsu Province(BK20210920 and BK20231350);Jiangsu Agricultural Science and Technology Innovation Fund(Cx223125);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
Nucleotide second messengers are highly versatile signaling molecules that regulate a variety of key biological processes in bacteria.The best-studied examples are cyclic AMP(cAMP)and bis-(3'-5')-cyclic dimeric guanos...
funded by the National Natural Science Foundation of China(31601821 and 31770300);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA28110100);the National Key Research and Development Program of China(2018YFE0194000,2018YFD0100304,2016YFD0101006);the Special Fund for Henan Agriculture Research System(HARS-22-03-G3)。
Strigolactones(SLs),which are biosynthesized mainly in roots,modulate various aspects of plant growth and development.Here,we review recent research on the role of SLs and their cross-regulation with auxin,cytokinin,a...
This work was supported by ICMR,India(No.05/13/4/2014-NCD-III dt.22.12.2017)。
The tumor microenvironment(TME)is heterogeneous and contains a multiple cell population with surrounded immune cells,which plays a major role in regulating metastasis.The multifunctional pathways,Hedgehog(Hh),Wnt,Notc...
We thank all members of the Pelet and Martin labs for helpful discussions and comments on the manuscripts,Marta Schmitt and Clemence Viaridel for technical assistance.This study was supported by Swiss National Science Foundation grants(PP00P3139121)and the University of Lausanne.
Background:Commitment to a new cell cycle is controlled by a number of cellular signals.Mitogen-activated protein kinase(MAPK)pathways,which transduce multiple extracellular cues,have been shown to be interconnected w...
PTB was initially discovered as a polypyrimidine tract-binding protein (hence the name), which corresponds to a specific RNA-binding protein associated with heterogeneous ribonucleoprotein particle (hnRNP Ⅰ). The...
Aim: Protein L-isoaspartyl O-methyltransferase (PIMT) regulates cell adhesion in various cancer cell lines through activation of integrin av and the PI3K pathway. The epithelial mesenchymal transition (EMT) enabl...
The first cell fate choice in the mammalian embryo, the segregation of the inner cell mass (ICM) and trophectoderm (TE), is regulated by the mutually antagonistic effects of the transcription factors, Oct4 and Cdx...
Aim: Substantial colocalization of functionally independent a4 nicotinic acetylcholine receptors and 5-HT3 serotonin receptors on presynaptic terminals has been observed in brain. The present study was aimed at addre...
Exposure to pathogens induces antigen-presenting cells (APC) such as macrophages and dendritic cells (DC) to produce various endogenous mediators, including arachidonic acid (AA)-derived eicosanoids, cytokines, ...