MUSCONE

作品数:11被引量:26H指数:3
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相关领域:医药卫生理学更多>>
相关作者:段天璇魏宁漪马长华齐娜更多>>
相关机构:大连兆羿生物酮技术有限公司北京中医药大学桂林医学院更多>>
相关期刊:《沈阳药科大学学报》《Science Bulletin》《色谱》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金更多>>
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Compatible stability study of Xing NaoJing injection based on physical-chemical properties analysis
《TMR Modern Herbal Medicine》2019年第4期173-182,共10页Dong-Li Qi Chun-Xia Liang Yue-Lin Zhang Yan-Quan Gao Yue Xing Hong-Li Yan Bing Zhang Jia-Rong Xie Zhi-Dong Liu 
Objective:The clinical treatment of brain diseases is urgent. Xingnaojing (XNJ) injection is often used in combination with other injection drugs. Due to the possible interaction between the injections in vivo, the pa...
关键词:Xingnaojing injection STABILITY Compatibility Physical-chemical properties Adverse drug reaction MUSCONE d-borneol 
Synthesis of(R)-(−)-Muscone from(R)-5-Bromo-4-methylpentanoate:A Chiron Approach
《Chinese Journal of Chemistry》2015年第6期683-687,共5页Junwei Shen Yong Shi Weisheng Tian 
A synthesis of(R)-muscone(1),a valuable musk odorant,is presented.The stereogenic center of muscone was introduced from methyl(R)-5-bromo-4-methylpentanoate(5),a chiral pool molecule developed in our group,and the mac...
关键词:MUSCONE FRAGRANCES macrocycles chiral pool (R)-5-bromo-4-methylpentanoate 
Primary study of muscone's effect on cardiovascular system被引量:3
《沈阳药科大学学报》2008年第S1期93-94,共2页ZHU Xue-jing1,2,WU Qi-biao1,LI Hai-tao1,2(1.College of Traditional Chinese Medicine,Macao University of Science and Technology,Macao 00853,China 2.College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China) 
Objective To investigate the effect of muscone on cardiovascular system.Methods Experimental animals to divide muscone high、middle、low dose group(the mouse is 20 mg·kg-1,10 mg·kg-1,5.0 mg·kg-1;the rat is 10 mg·k...
关键词:MUSCONE CARDIOVASCULAR SYSTEM 
固相微萃取-气相色谱法测定醒脑静注射剂中的麝香酮被引量:12
《色谱》2005年第5期565-565,共1页魏宁漪 马长华 段天璇 
关键词:固相微萃取(solid phase microextraction) 气相色谱法(gas chromatography) 麝香酮(muscone) 中药制剂(Chinese herba preparation) 
Synthesis of 2,15-Hexadecanedione as a Precursor of Muscone被引量:4
《Chinese Journal of Chemistry》2005年第3期334-336,共3页郭媛 顾焕 史真 
Effect of Muscone on Neuronal Glutamate Transporter EAAC1 Expression in Rats with Acute Cerebral Ischemia被引量:5
《Chinese Journal of Integrated Traditional and Western Medicine》2003年第4期285-288,共4页梁辉 陈虎 高颖 蔡定芳 
This study was supported by the fund of "Hundred Persons Project" of Shan ghai Public Health Bureau (No. 97BR016)
Objective: To investigate muscone's neuroprotective action and it s mechanism in rats with acute cerebral ischemic injury. Methods: Rat focal ischemic model of middle cerebral artery occlusion(MCAO) was establi shed b...
关键词:muscone cerebral ischemia  neuronal glu tamate transporter NEUROPROTECTION 
Biomimetic synthesis for precursor of muscone被引量:2
《Chinese Science Bulletin》2001年第5期393-395,共3页Zhen Shi Juli Qiang Zheng Li 
the National Natural Science Foundation of China (Grant No. 29872032) ; the Provincial Natural Science Foundation of Shaanxi Province (Grant No. FF982134).
Muscone is a precious fragrant compound scarce in nature. Many attempts have been made to synthesize this unique natural product. In this work, the one-carbon unit transfer reaction of tetrahydrofolate coenzyme was in...
关键词:MUSCONE 2 15-hexadecanedione BIOMIMETIC synthesis. 
Enantioselective Hydrogenation of α,β-Unsaturated Cyclic Ketones by Double Asymmetric Induction Preparation of (R)-Muscone被引量:1
《Chinese Chemical Letters》1997年第6期477-478,共2页Bao Han XIE Shi Jie LU Hong Xiang FU Lan Yong GAO (State Key Laboratory for Oxo Srnthesis and Selective Oxidation Lanzhou Institute of Chemical Physics. Chinese Academy of Sciences, Lanzhou 730000) 
By ketal formation with chiral glycols like methyl or ethyl ester of tartaric acid,hydrogenation of ketals from the correspondingα,β-unsaturated 15-membered cyclic ketone produces (R)-muscone in good chemical and op...
关键词:Unsaturated Cyclic Ketones by Double Asymmetric Induction Preparation of MUSCONE 
An Improved Synthesis of dl-Muscone
《Chinese Chemical Letters》1997年第1期17-18,共2页Han Song CHEN Xiu Fang LIU Han Sheng XU (Department of Chemistry, Wuhan University, Wuhan 430072)(Current address: Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071) 
M. Stoll's total synthetic route for dl-muscone was improved. 2.15.Hexadecanedione was synthesized by PTC method and converted into dehydromuscones through intramolecular aldol reaction by the mixture of zinc chloride...
关键词:An Improved Synthesis of dl-Muscone 
麝香酮(muscone)的合成研究被引量:2
《广东药学》1995年第2期35-37,共3页林先顺 
本文简述从蓖麻油裂解所得的十一烯酸为起始原料,经酯化、还原、溴代、加成缩合、皂化、酸化、脱羧、酯化而得α、ω十五碳二酸二乙酯,进行分子内缩合,得环十五酮醇,再经脱水,甲基化后得dl-3-甲基十五烷酮,最后,经硅胶层折提纯,可得药...
关键词:麝香酮 合成工艺 蓖麻油 分子内缩合 中药材 
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