LYMPHOID

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DALT:the brain’s border patrol
《Cell Research》2024年第9期603-604,共2页Jang Hyun Park Jenolyn F.Alexander Leon C.D.Smyth Jonathan Kipnis 
Mucosal-associated lymphoid tissues are the immune structures that rapidly initiate local immune responses;the dura mater is the outermost layer of the meninges covering and connecting central nervous system(CNS)with ...
关键词：LYMPHOID IMMUNE 
Building early defenses
《Cell Research》2021年第10期1041-1042,共2页Yi Ding Avinash Bhandoola 
Innate lymphoid cells(ILCs)are considered as innate equivalents of T cells.Liu et al.used single-cell RNA sequencing to determine the proportions of ILCs in human fetal tissues,and additionally identified novel progen...
关键词：FETAL al. LYMPHOID 
Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells被引量：4
《Cell Research》2021年第10期1106-1122,共17页Chen Liu Yandong Gong Han Zhang Hua Yang Yang Zeng Zhilei Bian Qian Xin Zhijie Bai Man Zhang Jian He Jing Yan Jie Zhou Zongcheng Li Yanli Ni Aiqing Wen Yu Lan Hongbo Hu Bing Liu 
This study was supported by grants from the National Key R&D Program of China(2020YFA0112400,2019YFA0110200,2017YFA0103401,2016YFA0100601 and 2016YFA0502203);the National Natural Science Foundation of China(31425012,31930054,31871173,81890991,82025002,81871232,81800102 and 81900115);the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2017ZT07S347);the Beijing Municipal Science&Technology Commission(Z171100000417009 and Beijing Leading Talents Program Z171100001117159);the State Key Laboratory of Proteomics(SKLP-K202003);the Key Research and Development Program of Guangdong Province(2019B020234002).
Whereas the critical roles of innate lymphoid cells(ILCs)in adult are increasingly appreciated,their developmental hierarchy in early human fetus remains largely elusive.In this study,we sorted human hematopoietic ste...
关键词：FETAL LYMPHOID INTESTINE 
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing被引量：6
《Cell Research》2021年第5期554-568,共15页Luca Mazzurana Paulo Czarnewski Viktor Jonsson Leif Wigge Markus Ringnér Teresa CWilliams Avinash Ravindran Åsa KBjörklund Jesper Säfholm Gunnar Nilsson Sven-Erik Dahlén Ann-Charlotte Orre Mamdoh Al-Ameri Charlotte Höög Charlotte Hedin Sylwester Szczegielniak Sven Almer Jenny Mjösberg 
The research was supported by the Swedish Cancer Society,the Swedish Foundation for Strategic Research,the Swedish Foundation for Medical Research,the Swedish Research Council,the Knut and Alice Wallenberg foundation and Karolinska Institutet.
The impact of the microenvironment on innate lymphoid cell(ILC)-mediated immunity in humans remains largely unknown.Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcripti...
关键词：immunity LYMPHOID metabolism 
Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity被引量：6
《Cell Research》2020年第6期475-491,共17页Christoph S.N.Klose David Artis 
The work was supported by grants from the German Research Foundation(DFG,KL 2963/2-1 and SPP1937-KL 2963/3-1 to C.S.N.K.);the European Research Council(ERCEA,ERC Starting Grant#803087 to C.S.N.K.);the National Institutes of Health(NIH,AI074878,AI095466,AI095608 and AI102942 to D.A.);the Burroughs Wellcome Fund(to D.A.);the Crohn's&Colitis Foundation of America(to D.A.);Cure for IBD(to D.A.);the Rosanne H.Silberman Foundation(to D.A.).
The multifaceted organization of the immune system involves not only patrolling lymphocytes that constantly monitor antigenpresenting cells in secondary lymphoid organs but also immune cells that establish permanent t...
关键词：IMMUNITY LYMPHOID HOMEOSTASIS 
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